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9ALPHA,11ALPHA-METHYLENE-15S-HYDROXY-11A-DEOXY-11A-METHYLENE-THROMBA-5Z,13E-DIEN-1-OIC ACID

9ALPHA,11ALPHA-METHYLENE-15S-HYDROXY-11A-DEOXY-11A-METHYLENE-THROMBA-5Z,13E-DIEN-1-OIC ACID Structure
CAS No.
74034-56-3
Chemical Name:
9ALPHA,11ALPHA-METHYLENE-15S-HYDROXY-11A-DEOXY-11A-METHYLENE-THROMBA-5Z,13E-DIEN-1-OIC ACID
Synonyms
CTA2;Carbocyclic TxA2;CARBOCYCLIC THROMBOXANE A2;(+/-)CARBOCYCLIC THROMBOXANE;(Z)-7-[(2S)-3β-[(1E,3S)-3-Hydroxy-1-octenyl]bicyclo[3.1.1]heptan-2α-yl]-5-heptenoic acid;9ALPHA,11ALPHA-METHYLENE-15S-HYDROXY-11A-DEOXY-11A-METHYLENE-THROMBA-5Z,13E-DIEN-1-OIC ACID;5-Heptenoic acid, 7-[(2S,3R)-3-[(1E,3S)-3-hydroxy-1-octen-1-yl]bicyclo[3.1.1]hept-2-yl]-, (5Z)-
CBNumber:
CB8182957
Molecular Formula:
C22H36O3
Molecular Weight:
348.52
MOL File:
74034-56-3.mol
Modify Date:
2023/6/8 9:03:09
Request For Quotation

9ALPHA,11ALPHA-METHYLENE-15S-HYDROXY-11A-DEOXY-11A-METHYLENE-THROMBA-5Z,13E-DIEN-1-OIC ACID Properties

storage temp. Store at -20°C
solubility DMF: 50 mg/ml; DMSO: 25 mg/ml; Ethanol: 100 mg/ml; PBS pH 7.2: 100 μg/ml

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS02,GHS07
Signal word  Danger
Hazard statements  H225-H319
Precautionary statements  P210-P233-P240-P241-P242-P243-P264-P280-P303+P361+P353-P305+P351+P338-P337+P313-P370+P378-P403+P235-P501
NFPA 704
3
2 0

9ALPHA,11ALPHA-METHYLENE-15S-HYDROXY-11A-DEOXY-11A-METHYLENE-THROMBA-5Z,13E-DIEN-1-OIC ACID Chemical Properties,Uses,Production

Description

Carbocyclic thromboxane A2 (CTA2) is a stable analog of TXA2. CTA2 is a potent coronary vasoconstrictor and is effective at concentrations as low as 1 nM in cat coronary arteries. Unlike other vascular TP receptor agonists, CTA2 is a potent inhibitor of prostanoid-induced platelet aggregation. It inhibits arachidonic acid-induced aggregation with an IC50 value of 4-5 μM. CTA2 also exhibits selective and dose-dependent inhibition of TXB2 synthesis in rabbit platelets at concentrations between 1 and 100 μM.

Uses

Carbocyclic Thromboxane A2 is a stable analog of TXA2 which inhibits thromboxane-mediated vasoconstriction platelet aggregation. Also, it converts the thromboxane synthase (TXAS) heme cofactor to its 5-coordinate.

9ALPHA,11ALPHA-METHYLENE-15S-HYDROXY-11A-DEOXY-11A-METHYLENE-THROMBA-5Z,13E-DIEN-1-OIC ACID Preparation Products And Raw materials

Raw materials

Preparation Products

9ALPHA,11ALPHA-METHYLENE-15S-HYDROXY-11A-DEOXY-11A-METHYLENE-THROMBA-5Z,13E-DIEN-1-OIC ACID Suppliers

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Cayman Chemical Company 81
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Hubei Aiputi Bioengineering Co., Ltd. 58
MP Biomedicals, Inc. 81
Service Chemical Inc. 71
3B Scientific Corporation 47
CARBONE SCIENTIFIC CO.,LTD 30
Shanghai Hao Zhun Biological Technology Co., Ltd. 58
Shenzhen Xinbosheng Biological Technology Co., Ltd. 58

74034-56-3(9ALPHA,11ALPHA-METHYLENE-15S-HYDROXY-11A-DEOXY-11A-METHYLENE-THROMBA-5Z,13E-DIEN-1-OIC ACID)Related Search:

5-CAPROLEIC ACID CIS-5-DODECENOIC ACID 9ALPHA,11ALPHA-METHYLENE-15S-HYDROXY-11A-DEOXY-11A-METHYLENE-THROMBA-5Z,13E-DIEN-1-OIC ACID ISO-PROPYLCYCLOBUTANE 2-(3-ALLYL)-4-PENTEN-1-OL
TRIMETHYLENE OXIDE
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9ALPHA,11ALPHA-METHYLENE-15S-HYDROXY-11A-DEOXY-11A-METHYLENE-THROMBA-5Z,13E-DIEN-1-OIC ACID (+/-)CARBOCYCLIC THROMBOXANE (Z)-7-[(2S)-3β-[(1E,3S)-3-Hydroxy-1-octenyl]bicyclo[3.1.1]heptan-2α-yl]-5-heptenoic acid Carbocyclic TxA2 CTA2 CARBOCYCLIC THROMBOXANE A2 5-Heptenoic acid, 7-[(2S,3R)-3-[(1E,3S)-3-hydroxy-1-octen-1-yl]bicyclo[3.1.1]hept-2-yl]-, (5Z)- 74034-56-3