Chinese english Japanese Germany Korea
ChemicalBook > Product Catalog >Organic Chemistry >Nitrogen Compounds >1-(Triisopropylsilyl)-1H-pyrrolo[2,3-b]pyridin-5-ol

1-(Triisopropylsilyl)-1H-pyrrolo[2,3-b]pyridin-5-ol

1-(Triisopropylsilyl)-1H-pyrrolo[2,3-b]pyridin-5-ol Structure
CAS No.
685514-01-6
Chemical Name:
1-(Triisopropylsilyl)-1H-pyrrolo[2,3-b]pyridin-5-ol
Synonyms
1-(triisopropylsilyl)-1H-pyrrolo[2,3-b]pyridin-5-ol;1-triisopropylsilylpyrrolo[2,3-b]pyridin-5-ol;1-tri(propan-2-yl)silylpyrrolo[2,3-b]pyridin-5-ol;1-Triisopropylsilanyl-1H-pyrrolo[2,3-b]pyridin-5-ol;1-[tris(propan-2-yl)silyl]-1H-pyrrolo[2,3-b]pyridin-5-ol;1-[Tris(1-methylethyl)silyl]-1H-pyrrolo[2,3-b]pyridin-5-ol;1H-Pyrrolo[2,3-b]pyridin-5-ol, 1-[tris(1-methylethyl)silyl]-;1-[(2-methylpropan-2-yl)oxycarbonyl]piperidine-4-sulfonic acid
CBNumber:
CB81871753
Molecular Formula:
C16H26N2OSi
Molecular Weight:
290.48
MOL File:
685514-01-6.mol
MSDS File:
SDS
Modify Date:
2024/3/29 15:21:39
Request For Quotation

1-(Triisopropylsilyl)-1H-pyrrolo[2,3-b]pyridin-5-ol Properties

Boiling point 341.6±35.0 °C(Predicted)
Density 1.03±0.1 g/cm3(Predicted)
pka 8.50±0.40(Predicted)

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P264-P270-P271-P280-P301+P312-P302+P352-P304+P340-P305+P351+P338-P330-P332+P313-P337+P313-P362-P403+P233-P405-P501

1-(Triisopropylsilyl)-1H-pyrrolo[2,3-b]pyridin-5-ol Chemical Properties,Uses,Production

Synthesis

Add 10.8g (34mmol) of (1-(triisopropylsilyl)-1H-pyrrolo[2,3-b]pyridin-5-yl)boronic acid and 120mL of tetrahydrofuran to a round bottom flask equipped with a magnetic stirrer, an inert gas source and a separating funnel, and stir to dissolve; Add 34mL of 1mol/L sodium hydroxide solution and 4.60g (40.6mmol) of 30% hydrogen peroxide dropwise at 0°C. After the addition, React at 0°C for 1 hour and detect the reaction by TLC. Add 4.8g (20.24mmol) of sodium thiosulfate, adjust to pH=5 with 2mol/L hydrochloric acid, extract with ethyl acetate (2x200mL), combine the organic phases, wash with saturated brine in turn, dry with a sodium sulfate, and reduce Concentrate under pressure. The residue was purified by silica gel column chromatography [eluent: dichloromethane] to obtain 1-(Triisopropylsilyl)-1H-pyrrolo[2,3-b]pyridin-5-ol 9.4g, yield 95.0%.
1H-Pyrrolo[2,3-b]pyridin-5-ol, 1-[tris(1-methylethyl)silyl]-

1-(Triisopropylsilyl)-1H-pyrrolo[2,3-b]pyridin-5-ol Preparation Products And Raw materials

Raw materials

Preparation Products

2-((1H-Pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-(4-((4'-chloro-5,5-dimethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-yl)methyl)piperazin-1-yl)benzoic acid

1-(Triisopropylsilyl)-1H-pyrrolo[2,3-b]pyridin-5-ol Suppliers

Global( 46)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
Viyash Life Sciences Pvt Ltd +91-4023635052 +91-4023635052 Telangana, India 213 58 Inquiry
Lakshmi Farmachem +91-9948795885 +91-9550886476 Telangana, India 407 58 Inquiry
CLEARSYNTH LABS LTD. +91-22-45045900 Hyderabad, India 6351 58 Inquiry
Shanghai Yingrui Biopharma Co.,Ltd 21-33585366 CHINA 1320 58 Inquiry
career henan chemical co +86-0371-86658258 +8613203830695 China 29826 58 Inquiry
Labnetwork lnc. +86-27-50766799 +8618062016861 China 19994 58 Inquiry
Alfa Chemistry United States 24072 58 Inquiry
Hefei TNJ Chemical Industry Co.,Ltd. 0551-65418684 +8618949823763 China 25363 58 Inquiry
Yangzhou Qinyuan Pharmatech Co.,ltd +86-18752526868 China 71 58 Inquiry
Hangzhou MolCore BioPharmatech Co.,Ltd. +86-057181025280; +8617767106207 China 49739 58 Inquiry
Supplier Advantage
Viyash Life Sciences Pvt Ltd 58
Lakshmi Farmachem 58
CLEARSYNTH LABS LTD. 58
Shanghai Yingrui Biopharma Co.,Ltd 58
career henan chemical co 58
Labnetwork lnc. 58
Alfa Chemistry 58
Hefei TNJ Chemical Industry Co.,Ltd. 58
Yangzhou Qinyuan Pharmatech Co.,ltd 58
Hangzhou MolCore BioPharmatech Co.,Ltd. 58

685514-01-6(1-(Triisopropylsilyl)-1H-pyrrolo[2,3-b]pyridin-5-ol)Related Search:

2-[(1H-Pyrrolo[2,3-b]pyridin-5-yl)oxy]-4-[4-[[2-(4-chlorophenyl)-4,4-dimethylcyclohex-1-enyl]methyl]piperazin-1-yl]benzoic acid 1-((4'-chloro-5,5-dimethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-yl)methyl)piperazine ABT-199 Methyl 4-Fluoro-2-{1H-pyrrolo[2,3-b]pyridin-5-yloxy}benzoate 3-nitro-4-((tetrahydro-2H-pyran-4-yl)MethylaMino)benzenesulfonaMide
4'-chloro-5,5-diMethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-carbaldehyde 1H-PYRROLO[2,3-B]PYRIDIN-5-OL
chevron_left

1of2

chevron_right
1H-Pyrrolo[2,3-b]pyridin-5-ol, 1-[tris(1-methylethyl)silyl]- 1-[Tris(1-methylethyl)silyl]-1H-pyrrolo[2,3-b]pyridin-5-ol 1-triisopropylsilylpyrrolo[2,3-b]pyridin-5-ol 1-[(2-methylpropan-2-yl)oxycarbonyl]piperidine-4-sulfonic acid 1-[tris(propan-2-yl)silyl]-1H-pyrrolo[2,3-b]pyridin-5-ol 1-tri(propan-2-yl)silylpyrrolo[2,3-b]pyridin-5-ol 1-Triisopropylsilanyl-1H-pyrrolo[2,3-b]pyridin-5-ol 1-(triisopropylsilyl)-1H-pyrrolo[2,3-b]pyridin-5-ol 685514-01-6 C16H26N2OSi