ChemicalBook > Product Catalog >Chemical Reagents >Organic reagents >Aromatic ketones >2',5'-Dihydroxyacetophenone
2',5'-Dihydroxyacetophenone
- CAS No.
- 490-78-8
- Chemical Name:
- 2',5'-Dihydroxyacetophenone
- Synonyms
- 2,5-DIHYDROXYACETOPHENONE;1-(2,5-DIHYDROXYPHENYL)ETHAN-1-ONE;1-(2,5-DIHYDROXYPHENYL)ETHANONE;Ethanone, 1-(2,5-dihydroxyphenyl)-;2-hydroxy-1-(3-hydroxyphenyl)ethan-1-one;2,5-DHAP;ACETYLQUINOL;WLN: QR CQ BV1;QUINACETOPHENONE;Acetylhydroquinone
- CBNumber:
- CB8221168
- Molecular Formula:
- C8H8O3
- Molecular Weight:
- 152.15
- MOL File:
- 490-78-8.mol
- MSDS File:
- SDS
- Modify Date:
- 2024/7/24 17:31:20
| Melting point | 204-206 °C(lit.) |
|---|---|
| Boiling point | 234.6°C (rough estimate) |
| Density | 1.2143 (rough estimate) |
| refractive index | 1.4447 (estimate) |
| storage temp. | Store below +30°C. |
| solubility | dioxane: 50 mg/mL, clear |
| form | Crystals or Crystalline Powder |
| pka | 9.86±0.18(Predicted) |
| color | Yellow to yellow-green |
| Water Solubility | insoluble |
| BRN | 637903 |
| InChIKey | WLDWSGZHNBANIO-UHFFFAOYSA-N |
| LogP | 1.274 (est) |
| CAS DataBase Reference | 490-78-8(CAS DataBase Reference) |
| NIST Chemistry Reference | Ethanone, 1-(2,5-dihydroxyphenyl)-(490-78-8) |
| EPA Substance Registry System | Ethanone, 1-(2,5-dihydroxyphenyl)- (490-78-8) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313-P261-P280a-P304+P340-P305+P351+P338-P405-P501a | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/37/38 | |||||||||
| Safety Statements | 26-36 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | AM7700000 | |||||||||
| Hazard Note | Irritant | |||||||||
| TSCA | Yes | |||||||||
| HS Code | 29145000 | |||||||||
| NFPA 704 |
|
2',5'-Dihydroxyacetophenone price More Price(10)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | D107603 | 2′,5′-Dihydroxyacetophenone 97% | 490-78-8 | 25G | ₹8540.93 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | 8.18284 | 2′,5′-Dihydroxyacetophenone for synthesis | 490-78-8 | 10G | ₹4340 | 2022-06-14 | Buy |
| ALFA India | ALF-A12185-22 | 2',5'-Dihydroxyacetophenone, 98+% | 490-78-8 | 100g | ₹33076 | 2022-05-26 | Buy |
| ALFA India | ALF-A12185-14 | 2',5'-Dihydroxyacetophenone, 98+% | 490-78-8 | 25g | ₹8268 | 2022-05-26 | Buy |
| ALFA India | ALF-A12185-06 | 2',5'-Dihydroxyacetophenone, 98+% | 490-78-8 | 5g | ₹1986 | 2022-05-26 | Buy |
2',5'-Dihydroxyacetophenone Chemical Properties,Uses,Production
Description
2',5'-Dihydroxyacetophenone is a natural phenolic compound that is found in many plants. It has been shown to have anti-inflammatory properties through its ability to inhibit the production of pro-inflammatory cytokines, such as tumor necrosis factor alpha and interleukin 1 beta.
Chemical Properties
yellow to yellow-green crystals or
Uses
2',5'-Dihydroxyacetophenone is an intermediate used in various synthetic preparations of pharmaceutical goods, 1-(2,5-Dihydroxyphenyl)ethanone was untilized in the synthesis of new flavonoid fatty acid esters with anti-adipogenic and glucose consumption enhancing activities.
Preparation
Preparation by Fries rearrangement of hydroquinone diacetate,
with aluminium chloride(91%) (76%)(63–77%) (55–60%)
with zinc chloride in refluxing acetic acid (quantitative yield)
with boron trifluoride etherate in benzene at reflux (65%).
Application
2',5'-Dihydroxyacetophenone inhibits the formation of reactive oxygen species and nitric oxide in rat neutrophils. It also has the ability to reduce oxidative stress by scavenging free radicals and inhibiting lipid peroxidation. The underlying mechanism for these effects is not fully understood but may be due to its ability to act as a substrate for matrix-assisted laser desorption ionization (MALDI). This means that it can react with protocatechuic acid molecules that are present in the sample preparation chamber, leading to polymerase chain reaction (PCR) amplification.
2',5'-Dihydroxyacetophenone Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 380)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| BTC pharm India | +918790379245 | AndhraPradesh, India | 1269 | 58 | Inquiry |
| GLR Innovations | +91 9891111994 | New Delhi, India | 4542 | 58 | Inquiry |
| ALTRAKEM PHARMA LIFE SCIENCES PRIVATE LIMITED | +919966658228 | Hyderabad, India | 486 | 58 | Inquiry |
| PEE ESS AROMATICS | +919382160846 | Tamil Nadu, India | 53 | 58 | Inquiry |
| Biosyn Research Chemicals | +91-91-9346022300 +91-9346022300 | Telangana, India | 465 | 58 | Inquiry |
| REAX CHEMICALS | +91-9347443900 +91-9347443900 | Hyderabad, India | 169 | 58 | Inquiry |
| SVH BIOSCIENCES | +91-6303499280 +91-6303499280 | Hyderabad, India | 478 | 58 | Inquiry |
| chakrachem Lifesciences | +91 9902744663 | Hyderabad, India | 451 | 58 | Inquiry |
| JSK Chemicals | +919879767970 | Gujarat, India | 3756 | 58 | Inquiry |
| AVIGYABIOSCIENCES PRIVATE LIMITED | +91-9849533087 +91-9849533087 | Telangana, India | 156 | 58 | Inquiry |
| Supplier | Advantage |
|---|---|
| BTC pharm India | 58 |
| GLR Innovations | 58 |
| ALTRAKEM PHARMA LIFE SCIENCES PRIVATE LIMITED | 58 |
| PEE ESS AROMATICS | 58 |
| Biosyn Research Chemicals | 58 |
| REAX CHEMICALS | 58 |
| SVH BIOSCIENCES | 58 |
| chakrachem Lifesciences | 58 |
| JSK Chemicals | 58 |
| AVIGYABIOSCIENCES PRIVATE LIMITED | 58 |
490-78-8(2',5'-Dihydroxyacetophenone)Related Search:
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1-(2,5-dihydroxyphenyl)-ethanon
1-Acetyl-2,5-dihydroxybenzene
2,5-Dihydroxy-1-acetylbenzene
2’,5’-dihydroxy-acetophenon
Acetophenone, 2',5'-dihydroxy-
Acetylhydroquinone
QUINACETOPHENONE
2-Acetylhydroquinone
Quinacetophenone
2',5'-DIHYDROXYACETOPHENONE FOR SYNTHESI
1-(2,5-Dihydroxyphenyl)ethan-1-one, 2-Acetylhydroquinone
2,5- twohydroxyAcetophenone
WLN: QR CQ BV1
ACETYLQUINOL
2,5-DIHYDROXYPHENYL METHYL KETONE
2',5'-DIHYDROXYACETOPHENONE
2-ACETYL-1,4-DIHYDROXYBENZENE
2-ACETYLHYDROQUINONE
2',5'-Dihydroxyacetophenone 2-Acetylhydroquinone
2,5-Dihydroxyacetophenone, 98+%
2-Acethylhydroquinone
2,5-DIHYDROXYACETOPHENONE extrapure
2,5-Dihydroxyphenyl methyl ketone, 2-Acetyl-1,4-dihydroxybenzene, 2-Acetylhydroquinone, Acetylquinol, Quinacetophenone
2',5'-Dihydroxyacetophenone,97%
2',5'- Dihydroxyacetophnone
2′,5′-Dihydroxyacetophenone,2,5-Dihydroxyphenyl methyl ketone, 2-Acetyl-1,4-dihydroxybenzene, 2-Acetylhydroquinone, Acetylquinol, Quinacetophenone
2',5'-Dihydroxyaceto
2 ', 5'-hydroxyacetophenone
5'-Dihydroxyacetophenone
2',5'-Dihydroxyacetophenone>
2,5-DHAP
2,5-Dihydroxy-Acetophenone (Quinacetophenone -98 %)
2,5-DIHYDROXYACETOPHENONE
1-(2,5-DIHYDROXYPHENYL)ETHAN-1-ONE
1-(2,5-DIHYDROXYPHENYL)ETHANONE
Ethanone, 1-(2,5-dihydroxyphenyl)-
2-hydroxy-1-(3-hydroxyphenyl)ethan-1-one
2',5'- Di hyfeoxy acetophenone
2',5'-Dihydroxyacetophenone(Quinactophenone)
2',5'-Dihydroxyacetophenone, ≥ 98.0%
2',5'-Dihydroxyacetophenone
2',5'-Dihydroxyacetophenone(Quinactophenone)
490-78-8
490-78-9
HO2C6H3COCH3
BioChemical
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