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5,8-Dihydroxy-1,4-naphthoquinone

5,8-Dihydroxy-1,4-naphthoquinone Structure
CAS No.
475-38-7
Chemical Name:
5,8-Dihydroxy-1,4-naphthoquinone
Synonyms
NAPHTHAZARIN;5,8-Dihydroxynaphthoquinone;5,8-Dihydroxynaphthalene-1,4-dione;Naphthazarone;Naphthazarine;NAPHTHAZALINE;Mordant Black 37;Naphthazarin (6CI);5,8-Dihydroxy-1,4-n;Naphthazarin, 10 mM in DMSO
CBNumber:
CB8194974
Molecular Formula:
C10H6O4
Molecular Weight:
190.15
MOL File:
475-38-7.mol
MSDS File:
SDS
Modify Date:
2025/1/27 9:38:02

5,8-Dihydroxy-1,4-naphthoquinone Properties

Melting point 220-230 °C(lit.)
Boiling point 285.64°C (rough estimate)
Density 1.3366 (rough estimate)
refractive index 1.5280 (estimate)
storage temp. Sealed in dry,Room Temperature
pka 6.98±0.20(Predicted)
form powder to crystaline
color Dark red to Brown
Water Solubility Soluble in water (5520 mg/L 25.).
BRN 880561
CAS DataBase Reference 475-38-7(CAS DataBase Reference)
NIST Chemistry Reference 1,4-Naphthalenedione, 5,8-dihydroxy-(475-38-7)

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H302+H312+H332-H315-H319-H335
Precautionary statements  P280a-P304+P340-P305+P351+P338-P405-P501a-P261-P264-P270-P271-P280-P301+P312+P330-P302+P352+P312+P362+P364-P304+P340+P312-P305+P351+P338+P337+P313-P501
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  22-24/25-37/39-26
WGK Germany  3
RTECS  QL7970000
HS Code  2914409000
NFPA 704
1
2 0

5,8-Dihydroxy-1,4-naphthoquinone price More Price(2)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) 388513 5,8-Dihydroxy-1,4-naphthoquinone technical grade 475-38-7 1G ₹16887 2022-06-14 Buy
TCI Chemicals (India) D2070 5,8-Dihydroxy-1,4-naphthoquinone 475-38-7 1G ₹13000 2022-05-26 Buy
Product number Packaging Price Buy
388513 1G ₹16887 Buy
D2070 1G ₹13000 Buy

5,8-Dihydroxy-1,4-naphthoquinone Chemical Properties,Uses,Production

Chemical Properties

dark purple to brown-black powder

Preparation

1,8-Dinitronaphthalene and 1,5-Dinitronaphthalene mixture or both alone and one of sulfur 40% fuming sulfuric ACID reaction, the product (5, 8 – dihydroxy – naphthoquinone) into Sulfurous acid?hydrogen salt.

Definition

ChEBI: A naphthoquinone that is 1,4-naphthoquinone in which the hydrogens at positions 5 and 8 are replaced by hydroxy groups.

Purification Methods

It crystallises in red-brown needles with a green shine from EtOH. It also crystallises from hexane and is further purified by sublimation at 2-10mm. [Huppert et al. J Phys Chem 89 5811 1985.] It is sparingly soluble in H2O but soluble in alkalis. The diacetate forms golden yellow prisms from CHCl3, m 192-193o and the 5,8-dimethoxy derivative has m 157o (155o) (from pet ether) [Bruce & Thompson J Chem Soc 1089 1955, IR: Schmand & Boldt J Am Chem Soc 97 447 1975, NMR: Brockmann & Zeeck Chem Ber 101 4221 1968]. The monothiosemicarbazone has m 168o(dec) from EtOH [Gardner et al. J Am Chem Soc 74 2106 1952]. [Beilstein 8 H 412, 8 III 3600.]

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,8-Dihydroxy-[1,4]naphthoquinone ,8-Dihydroxy-1,4-naphthalenedione 1,4-Naphthoquinone, 5,8-dihydroxy- 2,3-Dihydro-1,4,5,8-naphthalenetetrone 5,8-dihydroxy-4-naphthalenedione 5,8-dihydroxy-4-naphthoquinone Naphthazarine Naphthazarone 5,8-DIHYDROXY-1,4-NAPHTHALENEDIONE 5,8-DIHYDROXY-1,4-NAPHTHOQUINONE DIHYDROXY-1,4-NAPHTHOQUINONE,5,8- 5,8-HYDROXY-1,4-NAPHTHOQUINONE NAPHTHAZALINE 5,8-DIHYDROXY-1,4-NAPHTHOQUINONE, TECH. 5,8-Dihydroxy-1,4-naphthoquinone,tech.90% 5,8-Dihydroxy-1,4-n 5,8-Dihydroxy-1,4-naphthoquinone,98% 5,8-Dihydroxy-1,4-naphthalenedione Naphthazarin 5,8-dihydroxy-2,3-dihydronaphthalene-1,4-dione 5,8-Dihydroxy-1,4-naphthoquinone> 1,4-Naphthalenedione, 5,8-dihydroxy- C.I.Mordant Black 37:C.I.57010 Mordant Black 37 5,8-Dihydroxynaphthoquinone NAPHTHAZARIN 5,8-Dihydroxynaphthalene-1,4-dione Naphthazarin (6CI) Naturally,Apoptosis,Naphthazarin,stress,microtubules,mitochondrial,AIF,Inhibitor,p21,lysosomal,inhibit,oxidative,p53-dependent,anti-tumor Naphthazarin, 10 mM in DMSO 475-38-7 HO2C10H4O2 Carbonyl Compounds C10 Building Blocks Organic Building Blocks Ketones API intermediates