Shikalkin

Shikalkin Structure
CAS No.
54952-43-1
Chemical Name:
Shikalkin
Synonyms
shiconin;Arnebin-4;SHIKALKIN;Nsc 291845;(+-)-Shikonin;(Rac)-Shikonin;Shikonin >=98% (HPLC);Shikonin (mixture of optical isomers, about 1:1);5,8-Dihydroxy-2-(1-hydroxy-4-methylpent-3-enyl)naphthalene-1,4-dione;5,8-dihydroxy-2-(1-hydroxy-4-methylpent-3-en-1-yl)naphthalene-1,4-dione
CBNumber:
CB3273506
Molecular Formula:
C16H16O5
Molecular Weight:
288.3
MOL File:
54952-43-1.mol
MSDS File:
SDS
Modify Date:
2023/8/29 17:14:30

Shikalkin Properties

Melting point 144-145 °C
Boiling point 567.4±50.0 °C(Predicted)
Density 1.373±0.06 g/cm3(Predicted)
storage temp. 2-8°C
solubility methanol: soluble1mg/mL
pka 7.34±0.20(Predicted)
form powder or solid
color red to brown
LogP 4.350 (est)

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07,GHS09
Signal word  Warning
Hazard statements  H302-H400
Precautionary statements  P273-P301+P312+P330
Hazard Codes  Xn,N
Risk Statements  22-50/53
Safety Statements  61
RIDADR  UN 3077 9 / PGIII
WGK Germany  3
NFPA 704
0
2 0

Shikalkin price More Price(2)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) S7576 Shikonin ≥98% (HPLC) 54952-43-1 10MG ₹41135 2022-06-14 Buy
Sigma-Aldrich(India) S7576 Shikonin ≥98% (HPLC) 54952-43-1 50MG ₹138083.7 2022-06-14 Buy
Product number Packaging Price Buy
S7576 10MG ₹41135 Buy
S7576 50MG ₹138083.7 Buy

Shikalkin Chemical Properties,Uses,Production

Uses

Shikonin has been used:

  • to enhance the anti-tumor activity of gefitinib on tyrosine kinase receptor epidermal growth factor receptor (EGFR) in wild-type lung cancer cells
  • as an inhibitor of renal aerobic glycosis and a potential
  • as an anti-inflammatory agent to test its role to improve lipopolysaccharide (LPS)-induced cardiac dysfunction
  • to stimulate bone marrow-derived macrophages (BMDMs) to test the effect of Interferon regulatory factor 1 on cell death

General Description

Shikonin is a major phytochemical compound extracted from the roots of Lithospermum erythrorhizon. It is a natural anthraquinone derivative.

Biochem/physiol Actions

Shikonin is a potent anti-fungal agent against C. albicans biofilms. It displays anti-oxidant and chemotherapeutic properties on human glioma cells.

Shikalkin Preparation Products And Raw materials

Raw materials

Preparation Products

Shikalkin Suppliers

Global( 65)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
Shaanxi Haibo Biotechnology Co., Ltd +undefined18602966907 China 1000 58 Inquiry
Nanjing Doge Biomedical Technology Co., Ltd +86-25-58227606 +86-15305155328 China 4128 58 Inquiry
Shaanxi Cuikang Pharmaceutical Technology Co., Ltd +8618829768577 China 1250 58 Inquiry
TargetMol Chemicals Inc. +1-781-999-5354 United States 19973 58 Inquiry
ZHEJIANG JIUZHOU CHEM CO., LTD +86-0576225566889 +86-13454675544 China 19947 58 Inquiry
ShenZhen Trendseen Biological Technology Co.,Ltd. 13417589054 China 11681 58 Inquiry
Henan Allgreen Chemical Co.,LTD +86-37155567971 +86-13633837469 China 5986 58 Inquiry
LEAPCHEM CO., LTD. +86-852-30606658 China 43348 58 Inquiry
Aladdin Scientific +1-+1(833)-552-7181 United States 57511 58 Inquiry
Shanghai Likang New Materials Co., Limited +86-16631818819 +86-17736933208 China 9311 58 Inquiry
5,8-Dihydroxy-2-(1-hydroxy-4-methylpent-3-enyl)naphthalene-1,4-dione SHIKALKIN 1,4-Naphthalenedione, 5,8-dihydroxy-2-(1-hydroxy-4-methyl-3-pentenyl)- (9ci) Arnebin-4 Nsc 291845 shiconin Shikonin (mixture of optical isomers, about 1:1) 1,4-Naphthalenedione, 5,8-dihydroxy-2-(1-hydroxy-4-methyl-3-penten-1-yl)- Shikonin >=98% (HPLC) (+-)-Shikonin (Rac)-Shikonin 5,8-dihydroxy-2-(1-hydroxy-4-methylpent-3-en-1-yl)naphthalene-1,4-dione Inhibitor,inhibit,Shikalkin,(Rac) Shikonin,(Rac)Shikonin,(Rac)-Shikonin 54952-43-1 Inhibitors Coronavirus