5,6-Dihydro-2,3-(methylenedioxy)-9,10-dimethoxy-13-methyldibenzo[a,g]quinolizinium
- CAS No.
- 54260-72-9
- Chemical Name:
- 5,6-Dihydro-2,3-(methylenedioxy)-9,10-dimethoxy-13-methyldibenzo[a,g]quinolizinium
- Synonyms
- 13-Methylberberine;13-Methylberberinium Chlorid;13-Methylberberine (chloride);13-methylberberine/13-Methylberberine chloride;2,3-(Methylenedioxy)-9,10-dimethoxy-13-methyl-5H,6H-dibenzo[a,g]quinolizin-7-ium;9,10-Dimethoxy-13-methyl-5,6-dihydrobenzo[g]-1,3-benzodioxolo[5,6-a]quinolizinium;5,6-Dihydro-2,3-(methylenedioxy)-9,10-dimethoxy-13-methyldibenzo[a,g]quinolizinium;inhibit,Inhibitor,13 Methylberberine chloride,13Methylberberine chloride,Interleukin Related,13-Methylberberinium
- CBNumber:
- CB82266822
- Molecular Formula:
- C21H20ClNO4
- Molecular Weight:
- 385.8408
- MOL File:
- 54260-72-9.mol
- Modify Date:
- 2024/7/2 8:55:19
5,6-Dihydro-2,3-(methylenedioxy)-9,10-dimethoxy-13-methyldibenzo[a,g]quinolizinium Chemical Properties,Uses,Production
Description
13-Methylberberine (13-MB) (chloride) is a 13-methyl-substituted derivative of berberine . Berberine is a widely distributed berberidaceaen alkaloid found in plant tissues that has antibacterial, anti-inflammatory, antitumor, anti-obesity, and hypercholesterolemic activity. 13-MB has improved antibacterial activity against S. aureus (MIC = 125 μg/ml) and improved antitumor activity with a mean GI50 value of 11.7 μM, as compared to berberine. 13-MB also induces down-regulation of adipocyte differentiation transcription factors, reduces de novo lipid synthesis, and accumulates in murine 3T3-L1 adipocytes at higher levels than berberine, suggesting improved anti-obesity activity.
Uses
13-Methylberberinium Chloride can be used to treat and prevent immunoinflammatory dermal disorders. It can also be used in synthesis to result in derivatives that can be used to treat nerve diseases and anti-infective agents.
5,6-Dihydro-2,3-(methylenedioxy)-9,10-dimethoxy-13-methyldibenzo[a,g]quinolizinium Preparation Products And Raw materials
Raw materials
Preparation Products
Supplier | Tel | Country | ProdList | Advantage | Inquiry |
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Chengdu GLP biotechnology Co Ltd | 028-87075086 13350802083 | CHINA | 1824 | 58 | Inquiry |
Chengdu Biopurify Phytochemicals Ltd. | +86-28-82633860 +86-18080483897 | China | 3424 | 58 | Inquiry |
Xi'an Kono chem co., Ltd., | 029-86107037 13289246953 | China | 2995 | 58 | Inquiry |
Shaanxi Pioneer Biotech Co., Ltd . | +8613259417953 | China | 3000 | 58 | Inquiry |
Shaanxi Dideu Medichem Co. Ltd | +86-29-87569266 15319487004 | China | 4088 | 58 | Inquiry |
TargetMol Chemicals Inc. | +1-781-999-5354 | United States | 19973 | 58 | Inquiry |
Aladdin Scientific | +1-+1(833)-552-7181 | United States | 52927 | 58 | Inquiry |
Chengdu Alfa Biotechnology Co.,Ltd. | 028-028-85142057 19983342022 | China | 1979 | 58 | Inquiry |
Olix (Shanghai) Pharmaceutical Technology Co., Ltd | 17316404525 | China | 9652 | 58 | Inquiry |
RENI Pharmaceutical Technology Co., Ltd | 028-87865381 18108190480 | China | 3302 | 58 | Inquiry |
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