13-Methyl[1,3]benzodioxolo[5,6-c][1,3]dioxolo[4,5-i]phenanthridine-14(13H)-one

13-Methyl[1,3]benzodioxolo[5,6-c][1,3]dioxolo[4,5-i]phenanthridine-14(13H)-one Structure
CAS No.
548-30-1
Chemical Name:
13-Methyl[1,3]benzodioxolo[5,6-c][1,3]dioxolo[4,5-i]phenanthridine-14(13H)-one
Synonyms
Oxysanguinarine;Oxosanguinarine;8-Oxosanguinarine;Hydroxysanguinarine;Colistin Sulfate Impurity 3;13-Methyl[1,3]benzodioxolo[5,6-c]-1,3-dioxolo[4,5-i]phenanthridin-14(13H)-one;13-Methyl[1,3]benzodioxolo[5,6-c][1,3]dioxolo[4,5-i]phenanthridine-14(13H)-one;[1,3]Benzodioxolo[5,6-c]-1,3-dioxolo[4,5-i]phenanthridin-14(13H)-one, 13-methyl-;13-Methyl-[1,3]dioxolo[4',5':4,5]benzo[1,2-c][1,3]dioxolo[4,5-i]phenanthridin-14(13H)-one;13-Methyl-[1,3]dioxolo[4',5':4,5]benzo[1,2-c][1,3]dioxolo[4,5-i]phenanthridin-14(13H)-one
CBNumber:
CB82321839
Molecular Formula:
C20H13NO5
Molecular Weight:
347.32
MOL File:
548-30-1.mol
MSDS File:
SDS
Modify Date:
2023/5/21 10:59:17

13-Methyl[1,3]benzodioxolo[5,6-c][1,3]dioxolo[4,5-i]phenanthridine-14(13H)-one Properties

Melting point 223-224 °C
Boiling point 628.7±55.0 °C(Predicted)
Density 1.509±0.06 g/cm3(Predicted)
storage temp. Store at -20°C
pka -1.58±0.20(Predicted)

13-Methyl[1,3]benzodioxolo[5,6-c][1,3]dioxolo[4,5-i]phenanthridine-14(13H)-one Chemical Properties,Uses,Production

Description

An a-naphthaphenanthridine alkaloid, this base occurs in the roots of Sanguinaria canadensis. It is separated from the remaining bases by chromatography and purified by crystallization from CHC13 followed by sublimation in a high vacuum. It is optically inactive and may also be prepared by oxidation of sanguinarine nitrate by potassium ferricyanide in alkaline solution. No salts of this alkaloid have been prepared.

Uses

Hydroxysanguinarine can be used to treat coronavirus infection.

References

Spiithetal., Ber., 70, 1677 (1936)
Schlemmer, Gempp., Arch. Pharm., 276,506 (1938)

13-Methyl[1,3]benzodioxolo[5,6-c][1,3]dioxolo[4,5-i]phenanthridine-14(13H)-one Preparation Products And Raw materials

Raw materials

Preparation Products

13-Methyl[1,3]benzodioxolo[5,6-c][1,3]dioxolo[4,5-i]phenanthridine-14(13H)-one Suppliers

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13-Methyl[1,3]benzodioxolo[5,6-c][1,3]dioxolo[4,5-i]phenanthridine-14(13H)-one 13-Methyl[1,3]benzodioxolo[5,6-c]-1,3-dioxolo[4,5-i]phenanthridin-14(13H)-one Oxosanguinarine Oxysanguinarine Hydroxysanguinarine [1,3]Benzodioxolo[5,6-c]-1,3-dioxolo[4,5-i]phenanthridin-14(13H)-one, 13-methyl- 8-Oxosanguinarine 13-Methyl-[1,3]dioxolo[4',5':4,5]benzo[1,2-c][1,3]dioxolo[4,5-i]phenanthridin-14(13H)-one antimalarial,resistant,Parasite,inhibit,Plasmodium,Oxysanguinarine,falciparum strain,Inhibitor Colistin Sulfate Impurity 3 13-Methyl-[1,3]dioxolo[4',5':4,5]benzo[1,2-c][1,3]dioxolo[4,5-i]phenanthridin-14(13H)-one 548-30-1