CODEINE HYDROCHLORIDE

CODEINE HYDROCHLORIDE Structure
CAS No.
1422-07-7
Chemical Name:
CODEINE HYDROCHLORIDE
Synonyms
Codeinum Hcl;NUXLENPAZQNFAM-FFHNEAJVSA-N;CODEINE HYDROCHLORIDE DIHYDRATE;(4R,4aR,7S,7aR,12bS)-9-Methoxy-3-methyl-2,3,4,4a,7,7a-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinolin-7-ol hydrochloride
CBNumber:
CB8237693
Molecular Formula:
C18H22ClNO3
Molecular Weight:
335.83
MOL File:
1422-07-7.mol
Modify Date:
2023/5/4 15:13:38

CODEINE HYDROCHLORIDE Properties

Melting point ~280° with some decompn
alpha D22 -108°
storage temp. 2-8°C
solubility Soluble in water, slightly soluble in ethanol (96 per cent), practically insoluble in cyclohexane.

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07,GHS05
Signal word  Danger
Hazard statements  H302-H362-H318-H317
Precautionary statements  P280-P305+P351+P338-P310-P201-P260-P263-P264-P270-P308+P313-P261-P272-P280-P302+P352-P333+P313-P321-P363-P501-P264-P270-P301+P312-P330-P501
Toxicity LD50 s.c. in mice: 300 mg/kg (Eddy, Sumwalt)

CODEINE HYDROCHLORIDE Chemical Properties,Uses,Production

Chemical Properties

White or almost white, crystalline powder or small, colourless crystals.

Uses

Opioid receptor agonist; analgesic.

Contact allergens

Codeine has been reported as an occupational sensitizer in workers in the production of opium alkaloids. Codeine has been responsible for fixed drug eruptions or generalized dermatitis. Cross-sensitivity is expected to morphine.

CODEINE HYDROCHLORIDE Preparation Products And Raw materials

Raw materials

Preparation Products

CODEINE HYDROCHLORIDE DIHYDRATE Codeinum Hcl (4R,4aR,7S,7aR,12bS)-9-Methoxy-3-methyl-2,3,4,4a,7,7a-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinolin-7-ol hydrochloride NUXLENPAZQNFAM-FFHNEAJVSA-N 1422-07-7 C18H21NO3HCl2H2O