PPT
- CAS No.
- 263717-53-9
- Chemical Name:
- PPT
- Synonyms
- PPT;-triyl)trisphenol;Propylpyrazole Triol;1,3,5-tris(4-hydroxyphenyl)-4-propylpyrazole;1,3,5-TRIS(4-HYDROXYPHENYL)-4-PROPYL-1H-PYRAZOLE;4,4',4''-(4-Propyl-1H-pyrazole-1,3,5-triyl)triphenol;4,4',4''-(4-Propyl-1H-pyrazole-1,3,5-triyl)triphenol;4,4',4''-(4-PROPYL-[1H]-PYRAZOLE-1,3,5-TRIYL)TRISPHENOL;Phenol, 4,4',4''-(4-propyl-1H-pyrazole-1,3,5-triyl)tris-;Estrogen Receptor/ERR,inhibit,Inhibitor,Propyl pyrazole triol
- CBNumber:
- CB8245076
- Molecular Formula:
- C24H22N2O3
- Molecular Weight:
- 386.44
- MOL File:
- 263717-53-9.mol
- Modify Date:
- 2023/6/30 15:45:59
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H315-H319-H335 |
| Precautionary statements | P261-P264-P271-P280-P302+P352-P304+P340+P312-P305+P351+P338-P332+P313-P337+P313-P403+P233-P405-P501 |
| WGK Germany | 3 |
PPT Chemical Properties,Uses,Production
Uses
PPT is a potent and specific ERα agonist.
General Description
Estrogen receptor α (ERα) is a member of the nuclear receptor superfamily. It is also known as ESR1 (estrogen receptor). It is located on human chromosome 6q25.1.
1,3,5-tris(4-hydroxyphenyl)-4-propyl-1H-pyrazole is also termed as PPT. ERα is found in the nuclear and extranuclear sites in principal and inhibitory neurons.
Biological Activity
Potent, subtype-selective estrogen receptor agonist (EC 50 ~ 200 pM); displays 410-fold selectivity for ER α over ER β . Prevents ovariectomy-induced weight gain and loss of bone mineral density, and induces gene expression in the hypothalamus following systemic administration in vivo .
PPT Preparation Products And Raw materials
Raw materials
Preparation Products
PPT Suppliers
Global( 59)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | China | 32760 | 60 | Inquiry |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | United States | 19892 | 58 | Inquiry |
| Career Henan Chemica Co | +86-0371-86658258 +8613203830695 | China | 30253 | 58 | Inquiry |
| Aladdin Scientific | +1-+1(833)-552-7181 | United States | 57511 | 58 | Inquiry |
| Amadis Chemical Company Limited | 571-89925085 | China | 131980 | 58 | Inquiry |
| Xiamen Huijia Biological Technology Co., Ltd. | 0592-6020891 | CHINA | 6979 | 58 | Inquiry |
| Shanghai Jijin Chemical Technology Co., Ltd. | 400-002-6926 15900443528 | CHINA | 6617 | 58 | Inquiry |
| Beijing Zhijie Fangyuan Technology Co., Ltd. | 010-82897201 15810200961 | CHINA | 6984 | 58 | Inquiry |
| Shanghai Hao Zhun Biological Technology Co., Ltd. | 15800340161 | CHINA | 6846 | 58 | Inquiry |
| Beijing Shengke Boyuan Biotechnology Co., Ltd. | 010-62968438 | CHINA | 6011 | 58 | Inquiry |
263717-53-9(PPT)Related Search:
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4,4',4''-(4-PROPYL-[1H]-PYRAZOLE-1,3,5-TRIYL)TRISPHENOL
1,3,5-TRIS(4-HYDROXYPHENYL)-4-PROPYL-1H-PYRAZOLE
PPT
Propylpyrazole Triol
-triyl)trisphenol
Phenol, 4,4',4''-(4-propyl-1H-pyrazole-1,3,5-triyl)tris-
4,4',4''-(4-Propyl-1H-pyrazole-1,3,5-triyl)triphenol
1,3,5-tris(4-hydroxyphenyl)-4-propylpyrazole
Estrogen Receptor/ERR,inhibit,Inhibitor,Propyl pyrazole triol
4,4',4''-(4-Propyl-1H-pyrazole-1,3,5-triyl)triphenol
263717-53-9
Intracellular receptor
Nuclear Receptors