Unii-p9vxv1408y
- CAS No.
- 866021-48-9
- Chemical Name:
- Unii-p9vxv1408y
- Synonyms
- Ceftaroline;4-[2-[[(6R;Unii-p9vxv1408y;Ceftarolin Fosamil;Ceftaroline Impurity8;Ceftaroline USP/EP/BP;Unii-p9vxv1408y USP/EP/BP;Ceftaroline Fosamil Acetate Hydrate;7R)-2-Carboxy-7-[[(2Z)-(ethoxyimino)[5-(phosphonoamino)-1;acetic acid,(6R,7R)-7-[[(2Z)-2-ethoxyimino-2-[5-(phosphonoamino)
- CBNumber:
- CB82496122
- Molecular Formula:
- Molecular Weight:
- 0
- MOL File:
- Mol file
- MSDS File:
- SDS
- Modify Date:
- 2023/5/4 17:34:43
Unii-p9vxv1408y Chemical Properties,Uses,Production
Antimicrobial activity
A semisynthetic cephalosporin formulated as the water-soluble fosamil acetate prodrug for intravenous administration. Its properties are similar to those of ceftobiprole, with which it shares an enhanced affinity for penicillin-binding protein 2′ (2a) of methicillin-resistant Staph. aureus. It is hydrolyzed by extended-spectrum β-lactamases and is not active against Amp-C derepressed strains of Gram-negative bacilli.
Pharmacokinetics
Cmax 600 mg intravenous (1-h infusion): 19 mg/L end infusion
Plasma half-life: 2.6 h
Volume of distribution: 0.37 L/kg
Plasma protein binding :<20%
Like ceftobiprole, ceftaroline fosamil is rapidly hydrolyzed in
plasma after intravenous infusion and excreted principally in urine.
In preliminary clinical studies it appears to be well tolerated.
Unii-p9vxv1408y Preparation Products And Raw materials
Raw materials
Preparation Products
Supplier | Tel | Country | ProdList | Advantage | Inquiry |
---|---|---|---|---|---|
Vista Inc. | 09177778907 | Maharashtra, India | 7 | 58 | Inquiry |
Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | China | 21675 | 55 | Inquiry |
BOC Sciences | +1-631-485-4226 | United States | 19553 | 58 | Inquiry |
Chongqing Chemdad Co., Ltd | +86-023-6139-8061 +86-86-13650506873 | China | 39916 | 58 | Inquiry |
career henan chemical co | +86-0371-86658258 +8613203830695 | China | 29826 | 58 | Inquiry |
ENBRIDGE PHARMTECH CO., LTD. | +8613812269233 | China | 303 | 58 | Inquiry |
ANHUI WITOP BIOTECH CO., LTD | +8615255079626 | China | 23556 | 58 | Inquiry |
Shaanxi Dideu Medichem Co. Ltd | +86-029-89586680 +86-18192503167 | China | 9030 | 58 | Inquiry |
AFINE CHEMICALS LIMITED | +86-0571-85134551 | China | 15395 | 58 | Inquiry |
Baoji Guokang Healthchem co.,ltd | +8615604608665 15604608665 | CHINA | 9427 | 58 | Inquiry |
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- Mar 25,2022
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