Chinese english Japanese Germany Korea
ChemicalBook > Product Catalog >Analytical Chemistry >Standard >Pharmaceutical Impurity Reference Standards >PTEROIC ACID

PTEROIC ACID

PTEROIC ACID Structure
CAS No.
119-24-4
Chemical Name:
PTEROIC ACID
Synonyms
4-(((2-AMino-4-oxo-3,4-dihydropteridin-6-yl)Methyl)aMino)benzoic acid;Pyrofolic acid;4-[(2-amino-4-keto-1H-pteridin-6-yl)methylamino]benzoic acid;NSC 14972;PTEROIC ACID;Butterfly acid;Pteroic Acid (>Pteroic acid >=93%;Pteroic Acid (>85%);Folic acid iMpurity D
CBNumber:
CB8254618
Molecular Formula:
C14H12N6O3
Molecular Weight:
312.28
MOL File:
119-24-4.mol
MSDS File:
SDS
Modify Date:
2023/5/4 17:34:32
Request For Quotation

PTEROIC ACID Properties

Melting point >400℃
Boiling point 610.0±65.0 °C(Predicted)
Density 1.69
storage temp. 2-8°C
solubility Aqueous Base (Slightly), DMSO (Slightly)
pka 4.65±0.10(Predicted)
color Light Yellow to Brown

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P280-P261-P271
WGK Germany  3
HS Code  2933599590

PTEROIC ACID price More Price(4)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) P1781 Pteroic acid ≥93% 119-24-4 25MG ₹8649.18 2022-06-14 Buy
Sigma-Aldrich(India) P1781 Pteroic acid ≥93% 119-24-4 50MG ₹14527.15 2022-06-14 Buy
Sigma-Aldrich(India) PHR2002 Folic Acid Impurity D Pharmaceutical Secondary Standard; Certified Reference Material 119-24-4 100MG ₹59710.7 2022-06-14 Buy
Sigma-Aldrich(India) P1781 Pteroic acid ≥93% 119-24-4 100MG ₹25839.28 2022-06-14 Buy
Product number Packaging Price Buy
P1781 25MG ₹8649.18 Buy
P1781 50MG ₹14527.15 Buy
PHR2002 100MG ₹59710.7 Buy
P1781 100MG ₹25839.28 Buy

PTEROIC ACID Chemical Properties,Uses,Production

Uses

Pteroic Acid is a constituent as well as a degradation product of Folid Acid (F680300) formed via anzymatic hydrolysis. has been shown to activate the glutamylation of methotrexate by folylpolyglutama te synthetase.

General Description

Folic Acid Impurity D is an impurity of the water-soluble B-vitamin, folic acid. Folic Acid is generally used in the treatment of certain types of anemia.
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

Enzyme inhibitor

This metabolite (FWfree-acid = 312.29 g/mol; CAS 119-24-4), also known as 4-[[(2-amino-1,4-dihydro-4-oxo-6-pteridinyl)methyl]amino]benzoic acid, is a structural component of folates. Pteroic acid is a growth factor for a number of Enterococci. Pteroic acid is a yellow powder that is slightly soluble in aqueous NaOH. The lmax values in 0.1 M NaOH are 255, 275, and 365 nm (e = 26300, 23400, and 8900 M–1cm–1, respectively). Target(s): arylamine N-acetyltransferase; dihydrofolate reductase; dihydrofolate synthetase, weakly inhibited; dihydropteroate synthase; glutamate carboxypeptidase; and xanthine oxidase.

Purification Methods

Crystallise it from dilute HCl. Dry it in vacuo. Hygroscopic IRRITANT. [Nair et al. J Org Chem 46 3152 1981, Beilstein 26 III/IV 3942.]

PTEROIC ACID Preparation Products And Raw materials

Raw materials

AcetaMide, 2,2,2-trifluoro-N-(4-iodophenyl)- N10-Trifluoroacetyl Pyrofolic Acid 4-[(2-amino-4-oxo-7,8-dihydro-1H-pteridin-6-yl)methylamino]benzoic acid DL-Glutamic acid, N-[4-[[(2-amino-1,4-dihydro-4-oxo-6-pteridinyl)methyl]amino]benzoyl]- CHEMBRDG-BB 5276151
Folic acid 6-HYDROXY-2,4,5-TRIAMINOPYRIMIDINE 4-Aminobenzoic acid
chevron_left

1of2

chevron_right

Preparation Products

Benzoic acid, 4-[[(2-amino-3,4-dihydro-4-oxo-6-pteridinyl)methyl]amino]-, 2,5-dioxo-1-pyrrolidinyl ester

PTEROIC ACID Suppliers

Global( 263)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
VGS SYNTHESIS PRIVATE LIMITED +91-9866975588 +91-9866975588 Hyderabad, India 1818 58 Inquiry
Gagri Global IT Services Pvt. Ltd. +91-40-27170174, Telangana, India 1321 58 Inquiry
CLEARSYNTH LABS LTD. +91-22-45045900 Hyderabad, India 6351 58 Inquiry
A.J Chemicals 91-9810153283 New Delhi, India 6124 58 Inquiry
Pharmaffiliates Analytics and Synthetics P. Ltd +91-172-5066494 Haryana, India 6773 58 Inquiry
SynZeal Research Pvt Ltd +1 226-802-2078 Gujarat, India 6522 58 Inquiry
Chemicea Pharmaceuticals Pvt Ltd +91-9881765045/+91-8796656135 Pune, India 825 58 Inquiry
Pharma Affiliates 172-5066494 Haryana, India 6761 58 Inquiry
Refsyn Biosciences Pvt., Ltd. 91-413-2200273 Tamil Nadu, India 226 58 Inquiry
Anant Pharmaceuticals Pvt. ltd +91 8550986868 Maharashtra, India 736 58 Inquiry
Supplier Advantage
VGS SYNTHESIS PRIVATE LIMITED 58
Gagri Global IT Services Pvt. Ltd. 58
CLEARSYNTH LABS LTD. 58
A.J Chemicals 58
Pharmaffiliates Analytics and Synthetics P. Ltd 58
SynZeal Research Pvt Ltd 58
Chemicea Pharmaceuticals Pvt Ltd 58
Pharma Affiliates 58
Refsyn Biosciences Pvt., Ltd. 58
Anant Pharmaceuticals Pvt. ltd 58

119-24-4(PTEROIC ACID)Related Search:

(2S)-2-[[4-[Bis[(2-aMino-4-oxo-1,4-dihydropteridin-6-yl)Methyl]aMino]benzoyl]aMino]pentanedioic Acid 2-Amino-7-(chloromethyl)pteridin-4(1H)-one 2-Amino-4-hydroxy-1H-pteridine Erinacine A Erinacin A 5-formyl-5,6,7,8-tetrahydropteroic acid
2-Amino-6-(chloromethyl)-4(3H)-pteridinone Folitixorin (Mixture of DiastereoMers) N-(4-aminobenzoyl)- D-Glutamic acid Folic acid 5-Methyl Tetrahedropteroic Acid (Mixture of DiastereoMers)
Folic Acid Impurity C N-(p-Aminobenzoyl)glutamic acid folic acid 5-Methyltetrahydrofolic acid 10-Formylfolic Acid
Folinic acid 6-HYDROXY-2,4,5-TRIAMINOPYRIMIDINE L-Tetrahydrofolic Acid
chevron_left

1of4

chevron_right
4-[(2-amino-4-oxo-1H-pteridin-6-yl)methylamino]benzoic acid 4-[(2-azanyl-4-oxo-1H-pteridin-6-yl)methylamino]benzoic acid 4-{[(2-Amino-4-hydroxypteridin-6-yl)methyl]amino}benzoic acid 4-[[(2-AMino-3,4-dihydro-4-oxo-6-pteridinyl)Methyl]aMino]benzoic Acid NSC 14972 p-[(2-AMino-4-hydroxy-6-pteridylMethyl)aMino]benzoic Acid Benzoic acid, 4-[[(2-aMino-3,4-dihydro-4-oxo-6-pteridinyl)Methyl]aMino]- Folic acid iMpurity D Folic acid iMpurity D Pteroic acid Pteroic Acid (>85%) Pteroic acid >=93% NSC 14972 4-[[(2-Amino-3,4-dihydro-4-oxo-6-pteridinyl)methyl]amino]benzoic acid 4-(((2-Amino-4-oxo-3,4-dihydropteridin-6-yl) PTEROIC ACID p-((2-amino-4-hydroxypteridin-6-yl)methylamino)benzoic acid PTEROIC ACID HYDRATE, 90% Folic acid impurity DQ: What is Folic acid impurity D Q: What is the CAS Number of Folic acid impurity D Q: What is the storage condition of Folic acid impurity D Q: What are the applications of Folic acid impurity D 4-[(2-amino-4-oxo-1H-pteridin-6-yl)methylamino]benzoic acid(119-24-4) 4-[(2-amino-4-oxo-8H-pteridin-6-yl)methylamino]benzoic acid Folic Acid Impurity 6（Folic Acid EP Impurity D） Methotrexate EP Impurity D Desmethyl Impurity Pteroic Acid (> 4-[[(2-Amino-4-oxo-1,4-dihydropteri Folic acid impurity D CRS 4-(((2-amino-4-hydroxypteridin-6-yl) Methotrexate EP Impurity D N-Desmethyl Impurity Pteroic acid(Instant type) Folic Acid Impurity 6 Folic acid EP Impurity D Pteroic acid - min95% 4-[(2-amino-4-keto-1H-pteridin-6-yl)methylamino]benzoic acid Pyrofolic acid 4-(((2-AMino-4-oxo-3,4-dihydropteridin-6-yl)Methyl)aMino)benzoic acid Butterfly acid 4-{[(2-amino-4-hydroxypteridin-6-yl)methyl]amino}benzoicaci Pteroic acid (7CI, 8CI) Folic Acid Hydrate EP Impurity D 119-24-4 C14H12N6O3 Heterocyclic Building Blocks Quinazolines Building Blocks Heterocycles Building Blocks Chemical Synthesis Heterocyclic Building Blocks Building Blocks Heterocyclic Building Blocks Quinazolines