Folinic acid
- CAS No.
- 58-05-9
- Chemical Name:
- Folinic acid
- Synonyms
- LEUCOVORIN;levoleucovorin;5-formyltetrahydrofolic acid;N5-Formyl-H4F;5-formyltetrahydrofolate;Leucal;10-Formyl-7,8-dihydrofolic acid;CS-1326;Corticel;leucoverin
- CBNumber:
- CB5681752
- Molecular Formula:
- C20H23N7O7
- Molecular Weight:
- 473.44
- MOL File:
- 58-05-9.mol
- Modify Date:
- 2024/4/10 11:19:08
| Melting point | 245°C (rough estimate) |
|---|---|
| Boiling point | 573.92°C (rough estimate) |
| alpha | D20 +14.26° (c = 3.42 as anhydr Ca salt) |
| Density | 1.4485 (rough estimate) |
| refractive index | 1.6800 (estimate) |
| storage temp. | under inert gas (nitrogen or Argon) at 2–8 °C |
| solubility | DMSO:172.5(Max Conc. mg/mL);364.35(Max Conc. mM) |
| pka | 3.1, 4.8, 10.4(at 25℃) |
| form | Solid |
| color | Pale Yellow to Light Yellow |
| Water Solubility | >1350g/L(25 ºC) |
| Stability | Hygroscopic |
| CAS DataBase Reference | 58-05-9(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P280-P301+P312-P302+P352-P305+P351+P338 |
Folinic acid Chemical Properties,Uses,Production
Chemical Properties
Crystals. Sparingly soluble in water.
Uses
Folinic Acid is used in combination with 5-fluorouracil in the treatment of colorectal cancers. It also functions as a useful antidotal therapy medication for decreasing the toxic effect of methotrexate overdosing.
Definition
ChEBI: A formyltetrahydrofolic acid in which the formyl group is located at position 5.
Folinic acid Preparation Products And Raw materials
Global( 133)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6351 | 58 | Inquiry |
| WESTON MEDICAL STORES | 08048250474Ext 432 | Punjab, India | 9 | 58 | Inquiry |
| Fresh Chemicals Industries | 08068441120Ext 696 | Gujarat, India | 1 | 58 | Inquiry |
| airuikechemical co., ltd. | +undefined86-15315557071 | China | 983 | 58 | Inquiry |
| Shanghai Daken Advanced Materials Co.,Ltd | +86-371-66670886 | China | 16208 | 58 | Inquiry |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | China | 21671 | 55 | Inquiry |
| career henan chemical co | +86-0371-86658258 +8613203830695 | China | 29897 | 58 | Inquiry |
| Xiamen AmoyChem Co., Ltd | +86-592-6051114 +8618959220845 | China | 6387 | 58 | Inquiry |
| Chongqing Chemdad Co., Ltd | +86-023-6139-8061 +86-86-13650506873 | China | 39916 | 58 | Inquiry |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | China | 49391 | 58 | Inquiry |
Related articles
- What is Folinic acid?
- Folinic acid is used to prevent severe toxic effects caused by methotrexate overdose or high-dose treatment.
- Aug 5，2021
58-05-9(Folinic acid)Related Search:
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5-formyl-5,6,7,8-tetrahydropteroyl-l-glutamicacid
leucoverin
5-formyl-5,6,7,8-tetrahydrofolate
N5-formyl-5,6,7,8-tetrahydrofolate
N5-formyl-tetrahydrofolate
2-[4-[(2-amino-5-formyl-4-oxo-1,6,7,8-tetrahydropteridin-6-yl)methylamino]benzoyl]aminopentanedioic acid
(6R,S)-5-Formyltetrahydrofolate
5-Formyl-5,6,7,8-tetrahydrofolic acid
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L-Glutamic acid, N-[4-[[(2-amino-5-formyl-1,4,5,6,7,8-hexahydro-4-oxo-6-pteridinyl)methyl]amino]benzoyl]- (9CI)
l-Leucovorin
N5-Formyl-5,6,7,8-tetrahydrofolic acid
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Welcovorin
N-[4-[[(2-Amino-5-formyl-1,4,5,6,7,8-hexahydro-4-oxopteridin-6-yl)methyl]amino]benzoyl]-L-glutamic acid
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Folinic acid, leucovorin
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