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Levomefolate calcium

Levomefolate calcium Structure
CAS No.
151533-22-1
Chemical Name:
Levomefolate calcium
Synonyms
l-5-methylfolate;Calcium levomefolate;L-5-Methyltetrahydrofolate calcium;LMCA;Deplin;Bodyfolin;Nutrifolin;L-5-MTHF-Ca;L-5-Methyltetra;6S-5-methylfolate
CBNumber:
CB11420680
Molecular Formula:
C20H27CaN7O6
Molecular Weight:
501.56
MOL File:
151533-22-1.mol
MSDS File:
SDS
Modify Date:
2024/8/4 20:11:12
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Levomefolate calcium Properties

Melting point >300°C
storage temp. Inert atmosphere,2-8°C
solubility Aqueous Acid (Heated), Water (Slightly, Heated)
form Solid
color Off-White to Light Yellow
Odor at 100.00?%. odorless
InChIKey CZDUXPNTZGHMRC-ZPZVDPIKNA-N
SMILES CN1[C@H](CNC2NC(N)=NC(=O)C1=2)CNC1C=CC(C(=O)N[C@H](C(=O)O)CCC(=O)O)=CC=1.[Ca] |&1:2,22,r|
CAS DataBase Reference 151533-22-1

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H319-H335-H302+H312+H332-H315-H302
Precautionary statements  P264-P280-P305+P351+P338-P337+P313P-P264-P280-P302+P352-P321-P332+P313-P362-P264-P270-P301+P312-P330-P501
Safety Statements  24/25
HS Code  29339900

Levomefolate calcium Chemical Properties,Uses,Production

Description

Levomefolate calcium (L-5-MTHF-Ca) is a synthetic derivative of folic acid, the predominant, naturally occurring form of folate. L-5-methyltetrahydrofolate, also known as levomefolic acid, is the primary biologically active form of folate. It is involved in many important in vivo process including DNAreproduction, the cysteine cycle and the regulation of homocysteine. It is also the form found in circulation and transported across membranes into tissues and across the blood-brain barrier. It can be used for the treatment of major depressive disorder, cardiovascular disease and cancer. It can be used for the treatment of hyperhomocysteinemia regularly found in hemodialysis patients.

Chemical Properties

Off-White to Pale Yellow Solid

brand name

Products containing levomefolate calcium Brand name: L-Methylfolate Calcium
Multi-ingredient medications containing levomefolate calcium drospirenone/ethinyl estradiol/levomefolate calcium systemic Brand names: Beyaz, Tydemy, Safyral, Rajani

Biological Functions

Levomefolate calcium is the calcium salt of L-5-methyltetrahydrofolic acid, and a member of the folate group of vitamins (Vitamin B9). It is the coenzymated and most active form of folic acid, which performs many vital cellular functions, including DNA reproduction, cysteine cycle and homocysteine regulation. L-5-Methyltetrahydrofolate calcium is used as in dietary supplements and has been proposed for treatment of cardiovascular disease.

Clinical Use

Folates are a class of water soluble compounds belonging to the Vitamin B complex which are essential for a number of metabolic functions, including processes involved in the development and metabolism of CNS and the production of DNA and RNA, primarily in infancy, adolescence and pregnancy.
Calcium Levomefolate is the active metabolic form of folates in the body.
Folate deficiency consequences can be as serious as birth defects (i.e. "spina bifida"), megaloblastic anaemia, and some types of depression.
Calcium Levomefolate can be the most effective treatment to remedy those deficiencies.
Calcium Levomefolate is formulated in many medical supplements for cases of folate deficiency or need for increased uptake; it is prescribed during pregnancy to prevent birth defects associated with CNS formation and functionality.
It is also the active ingredient in medicinal products prescribed for certain types of depression, disturbed behaviour and Mild Cognitive Impairment (MCI)

Side effects

Signs of a Levomefolate Calcium allergy: Skin rash Trouble breathing Swelling of the throat, lips, or face Wheezing Runny nose Itchy, watery eyes.
Anaphylaxis is a rare but life-threatening allergic reaction. Signs of anaphylaxis include: Tightening of the throat and airways Nausea Abdominal pain Vomiting Diarrhea Dizziness or lightheadedness Rapid or weak heart rate Reduced blood pressure Seizures Fainting

Levomefolate calcium Preparation Products And Raw materials

Raw materials

Preparation Products

Levomefolate calcium Suppliers

Global( 400)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
Anthem Biosciences Pvt Ltd +91-8066724000 +91-9900044575 Karnataka, India 38 58 Inquiry
Panvo Organics Pvt Ltd +91 9789806833 +91 9444351711 Tamil Nadu, India 23 58 Inquiry
Meteoric Biopharmaceuticals Pvt. Ltd. +91-8511121361 +91-8511121361 Mumbai, India 71 58 Inquiry
Ascott Pharma +91-9825331440 +91-9825331440 Gujarat, India 7 58 Inquiry
Global Calcium Pvt Ltd +91-8050750904 +91-8040554500 Karnataka, India 132 58 Inquiry
Aditya Chemicals +91-9825237294 +91-9909971523 Gujarat, India 38 58 Inquiry
Ralington Pharma +91-7948911722 +91-9687771722 Gujarat, India 1350 58 Inquiry
ProVentus Life Sciences Pvt Ltd +91-4428362047 +91-4447400141 Tamil Nadu, India 20 58 Inquiry
LUPIN LTD +91 124 4885000 / +91 124 3325000 New Delhi, India 191 58 Inquiry
CLEARSYNTH LABS LTD. +91-22-45045900 Hyderabad, India 6351 58 Inquiry
Supplier Advantage
Anthem Biosciences Pvt Ltd 58
Panvo Organics Pvt Ltd 58
Meteoric Biopharmaceuticals Pvt. Ltd. 58
Ascott Pharma 58
Global Calcium Pvt Ltd 58
Aditya Chemicals 58
Ralington Pharma 58
ProVentus Life Sciences Pvt Ltd 58
LUPIN LTD 58
CLEARSYNTH LABS LTD. 58

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  • What is Levomefolate calcium?
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Related Qustion

Levomefolate calcium Spectrum

Levomefolate calcium(151533-22-1)1HNMR

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(S)-2-(4-((((S)-2-AMino-5-Methyl-4-oxo-3,4,5,6,7,8-hexahydropteridin-6-yl)Methyl)aMino)benzaMido)pentanedioic acid, calciuM salt L-5- Methyl leucovorin Calcium (S)-2-(4-((((S)-2-amino-5-methyl-4-oxo-3,4,5,6,7,8-hexahydropteridin-6-yl)methyl)amino CALCIUML-5-METHYLTETRAHYDROFOLATE (6S)-N-[4-(2-Amino-1,4,5,6,7,8,-hexahydro-5-methyl-4-oxo-6-pteridinylmethylamino)benzoyl]-L-glutaminsure, Calciumsalz (1:1) METHYL FOLATE CALCIUM SALT(METAFOLIN)(P) Levomefolate calcium Levomefolate Calcium (Also See: M330135) L-5-Methyltetrahydrofolate calciuM(L-5-MTHF-Ca) N-[4-[[(2-Amino-1,4,5,6,7,8-hexahydro-5-methyl-4-oxo-6-pteridinyl)methyl]amino]benzoyl]-L-glutamic acid calcium salt Bodyfolin LMCA N-[4-[[[(6S)-2-AMino-3,4,5,6,7,8-hexahydro-5-Methyl-4-oxo-6-pteridinyl]Methyl]aMino]benzoyl]-L-glutaMic Acid CalciuM Salt Nutrifolin L-5-Methyletrahydrofolate calciuM L-5-MTHF-Ca Calcium (S)-2-(4-((((S)-2-amino-5-methyl-4-oxo-3,4,5,6,7,8-hexahydropteridin-6-yl)methyl)amino)be CalciuM (S)-2-(4-((((S)-2-aMino-5-Methyl-4-oxo-3,4,5,6,7,8-hexahydropteridin-6-yl)Methyl)aMino)benzaMido)-4-carboxybutanoate L-5-METHYLTETRAHYDROFOLATE CALCIUM 6S L-5-Methyltetrahydrofolate calcium 99% Deplin calcium laevo-5-methyl tetrahydrofolate Levomefolate (calcium salt) Folic Acid Impurity 3 L-5-Methyletrahydrofolate calcium salt 1-mcp1-methylcyclopropene Calcium Levomefolate (L-5-Methyltetrahydrofolate Calcium Salt) L-Glutamic acid, N-[4-[[[(6S)-2-amino-3,4,5,6,7,8-hexahydro-5-methyl-4-oxo-6-pteridinyl]methyl]amino]benzoyl]-, calcium salt (1:1) Calcium (6S)-5-methyl-tetrahydrofolate LEVOMEFOLIC CALIUM Levomefolate calcium USP/EP/BP L-5 methyl tetrahydrofolat calcium Patented C crystal L-Methylfolate, branded Magnafolate L-5-Methyltetrahydrofolate Calcium Levome or METHYL FOLATE L-5-methyl tetrahydrofolic (6S)-5-methyl-5,6,7,8-tetrahydropteroyl-L-glutamic acid, calcium salt CALCIUML-5-METHYLTETRAHYDROFOLATEr Levo MethylFolate Calcium (LMF). Levomefolate calcium (LMCA and BAY 86-7660) 6S-5-methylfolate Levomefolate CalciumQ: What is Levomefolate Calcium Q: What is the CAS Number of Levomefolate Calcium Q: What is the storage condition of Levomefolate Calcium Q: What are the applications of Levomefolate Calcium Levomefolate D4 calcium salt Calcium levomefolate L-5-Methyltetrahydrofolate calcium l-5-methylfolate (6S)-5-methyltetrahydrofolate calcium CALChemicalbookCIUML-5-METHYLTETRAHYDROFOLATE L-5-Methyltetra :4-ISOPROPYL-3-METHYLPHENOL 3228-02-2 Methyl Folate Calcium Salt (AS) L-5-Methyltetrahydrofolate calcium (L-5-MTHF) METHYL FOLATE CALCIUM SALT Calcium 5-methyltetrahydrofolate 13C5 (racemic) L-5-MTHF-Ca (L-5-Methyltetrahydrofolate-Ca) 6s-5-methyltetrahydro folatecalclum 151533-22-1 15133-22-1 C20H25CaN7O6