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6,11-Di-O-Methyl ErythroMycin

6,11-Di-O-Methyl ErythroMycin Structure
CAS No.
81103-14-2
Chemical Name:
6,11-Di-O-Methyl ErythroMycin
Synonyms
11-O-MethylclarithroMycin;Clarithromycin EP Impurity E;6,11-Di-O-Methyl ErythroMycin;Erythromycin, 6,11-di-O-methyl-;Clarithromycin USP Related Compound A;Clarithromycin EP Impurity E (USP RC A);Clarithromycin Impurity 5(Clarithromycin EP Impurity E);Clarithromycin EP Impurity E (Clarithromycin USP Related Compound A);Clarithromycin EP Impurity E/ Clarithromycin Related Compound A (6,11-Di-O-methylerythromycin A);(3R,4S,5S,6R,7R,9R,11R,12R,13R,14R)-6-(((2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-14-ethyl-13-hydroxy-4-(((2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyltetrahydro
CBNumber:
CB82550839
Molecular Formula:
C39H71NO13
Molecular Weight:
761.98
MOL File:
81103-14-2.mol
MSDS File:
SDS
Modify Date:
2025/1/26 16:22:08

6,11-Di-O-Methyl ErythroMycin Properties

Melting point 252-257 °C(Solv: dichloromethane (75-09-2); ethyl ether (60-29-7))
Boiling point 808.6±65.0 °C(Predicted)
Density 1.16±0.1 g/cm3(Predicted)
storage temp. -20°C Freezer, Under inert atmosphere
solubility Chloroform (Slightly), DMSO (Slightly, Heated), Methanol (Slightly, Heated)
pka 12.96±0.70(Predicted)
color White to Off-White

SAFETY

Risk and Safety Statements

HS Code  2932206000

6,11-Di-O-Methyl ErythroMycin Chemical Properties,Uses,Production

Uses

6,11-Di-O-methyl Erythromycin (Clarithromycin EP Impurity E) is a Di-O-alkyl Erythromycin (E649950) is an impurity of Clarithromycin (C559750). Clarithromycin impurity E per British Pharmacopoeia.

6,11-Di-O-Methyl ErythroMycin Preparation Products And Raw materials

Raw materials

Preparation Products

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6,11-Di-O-Methyl ErythroMycin 11-O-MethylclarithroMycin Clarithromycin EP Impurity E/3R,4S,5S,6R,7R,9R,11R,12R,13R,14R)-6-(((2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-14-ethyl-13-hydroxy-4-(((2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyltetrahydro-2H-pyran-2-yl)oxy)-7,12-di Clarithromycin EP Impurity E (USP RC A) Clarithromycin Impurity 5(Clarithromycin EP Impurity E) Clarithromycin EP Impurity E Erythromycin, 6,11-di-O-methyl- Clarithromycin EP Impurity E/ Clarithromycin Related Compound A (6,11-Di-O-methylerythromycin A) Clarithromycin EP impurity EQ: What is Clarithromycin EP impurity E Q: What is the CAS Number of Clarithromycin EP impurity E Q: What is the storage condition of Clarithromycin EP impurity E Q: What are the applications of Clarithromycin EP impurity E Clarithromycin USP Related Compound A (3R,4S,5S,6R,7R,9R,11R,12R,13R,14R)-6-(((2S,3R,4S,6R)-4-(Dimethylamino)-3-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-14-ethyl-13-hydroxy-4-(((2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyltetrahydro-2H-pyran-2-yl)oxy)-7,12-dimethoxy-3,5,7,9,11,13-hexamethyloxacyclotetradecane-2,10-dione (Clarithromycin Impurity) (3R,4S,5S,6R,7R,9R,11R,12R,13R,14R)-6-(((2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-14-ethyl-13-hydroxy-4-(((2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyltetrahydro (3R,4S,5S,6R,7R,9R,11R,12R,13R,14R)-6-(((2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-14-ethyl-13-hydroxy-4-(((2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyltetrahydro-2H-pyran-2-yl)oxy)-7,12-dimethoxy-3,5,7,9,11,13-hexamethyloxacyclotetradecane-2,10-dione Clarithromycin EP Impurity E (Clarithromycin USP Related Compound A) 81103-14-2 C39H71NO13 Carbohydrates & Derivatives Chiral Reagents Intermediates & Fine Chemicals Pharmaceuticals