L-Ribose
- CAS No.
- 24259-59-4
- Chemical Name:
- L-Ribose
- Synonyms
- L-RIBOSE;Ribose;L - RNA;L-D-Ribose;L-(+)-Ribos;L-(+)-RIBOSE;z052L-Ribose;L-Ribose >L-Ribose ,98%;L-PLUS-RIBOSE
- CBNumber:
- CB8256607
- Molecular Formula:
- C5H10O5
- Molecular Weight:
- 150.13
- MOL File:
- 24259-59-4.mol
- Modify Date:
- 2024/12/17 10:45:04
| Melting point | 81-82 °C(lit.) |
|---|---|
| alpha | 20 º (c=2,water) |
| Boiling point | 191.65°C (rough estimate) |
| Density | 1.1897 (rough estimate) |
| refractive index | 20 ° (C=1, H2O) |
| storage temp. | Inert atmosphere,Store in freezer, under -20°C |
| solubility | Methanol (Slightly), Water (Slightly) |
| form | Solid |
| pka | 12.22(at 25℃) |
| color | White to Off-White |
| Water Solubility | Soluble in water (100 mg/ml). |
| BRN | 1723084 |
| Stability | Stable. Combustible. Incompatible with strong oxidizing agents. |
| CAS DataBase Reference | 24259-59-4(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P305+P351+P338 | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/37/38-37-36-36/38 | |||||||||
| Safety Statements | 24/25-36-26-37/39 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | 246-110-4 | |||||||||
| F | 3-10 | |||||||||
| HS Code | 29400000 | |||||||||
| NFPA 704 |
|
L-Ribose price More Price(7)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | R4377 | L-(+)-Ribose | 24259-59-4 | 1G | ₹41037.58 | 2022-06-14 | Buy |
| TCI Chemicals (India) | R0068 | L-Ribose | 24259-59-4 | 1G | ₹3900 | 2022-05-26 | Buy |
| TCI Chemicals (India) | R0068 | L-Ribose | 24259-59-4 | 5G | ₹9700 | 2022-05-26 | Buy |
| TCI Chemicals (India) | R0068 | L-Ribose | 24259-59-4 | 25G | ₹19300 | 2022-05-26 | Buy |
| ottokemi | R 1330 | L-Ribose 98% | 24259-59-4 | 1mg | ₹3879 | 2022-05-26 | Buy |
L-Ribose Chemical Properties,Uses,Production
Chemical Properties
white crystals or powder
Uses
L-[1-13C]ribose is a compound useful in organic synthesis.
Definition
ribose: A monosaccharide, C5H10O5, rarely occurring free in nature but important as a component of RNA (ribonucleic acid). Its derivative deoxyribose, C5H10O4, is equally important as a constituent of DNA (deoxyribonucleic acid), which carries the genetic code in chromosomes.
Biosynthesis
L-ribose is the enantiomer of D-ribose, which occurs naturally. It is a building block of many novel nucleotide analogue anti-viral drugs. Bio-production of L-ribose relies on a two-step reaction: (i) conversion of L-arabinose to L-ribulose by the catalytic action of L-arabinose isomerase (L-AI) and (ii) conversion of L-ribulose to L-ribose by the catalytic action of L-ribose isomerase (L-RI, EC 5.3.1.B3) or mannose-6-phosphate isomerase (MPI, EC 5.3.1.8, alternately named as phosphomannose isomerase). Among the two enzymes, L-RI is a rare enzyme discovered in 1996 by Professor Izumori's group, whereas MPI is an essential enzyme in metabolic pathways in humans and microorganisms[1].
Synthesis
A method for converting inexpensive, naturally occurring D-ribose into L-ribose is by interconverting the hydroxy group at Cl and the hydroxymethyl group at C5. L-Ribose is prepared from D-ribose by (a) forming a hydroxy-protected D-ribose, (b) reducing the hydroxy-protected D-ribose to a protected tetrol, (c) converting the tetrol to a tetraester, such as a tetraacetate; (d) hydrolyzing the protecting group to form a hydroxymethyl tetraester; (e) oxidizing the hydroxymethyl group to form a tetraester aldehyde; and (f) hydrolysing the ester groups to yield L-ribose.
References
[1] M. Helanto. “Biotechnological production of l-ribose from l-arabinose.” Applied Microbiology and Biotechnology 83 1 (2009): 77–83.
L-Ribose Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| SNECOFRi Pvt Ltd | +91-9032850129 +91-9032850129 | Telangana, India | 403 | 58 | Inquiry |
| CHEMSWORTH | +91-261-2397244 | New Delhi, India | 6700 | 30 | Inquiry |
| A.J Chemicals | 91-9810153283 | New Delhi, India | 6100 | 58 | Inquiry |
| CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6257 | 58 | Inquiry |
| Central Drug House(P) Ltd. | 91-11-49404040 | New Delhi, India | 6157 | 58 | Inquiry |
| TCI Chemicals (India) Pvt. Ltd. | 1800 425 7889 | New Delhi, India | 6768 | 58 | Inquiry |
| Otto Chemie Pvt. Ltd. | +91 9820041841 | Mumbai, India | 5870 | 58 | Inquiry |
| Maas Pharma Chemicals | +91-9958666224 | Delhi, India | 1607 | 58 | Inquiry |
| Hebei Weibang Biotechnology Co., Ltd | +8615531157085 | China | 8806 | 58 | Inquiry |
| Capot Chemical Co.,Ltd. | +86-（0）57185586718 +86-13336195806 | China | 29793 | 60 | Inquiry |
| Supplier | Advantage |
|---|---|
| SNECOFRi Pvt Ltd | 58 |
| CHEMSWORTH | 30 |
| A.J Chemicals | 58 |
| CLEARSYNTH LABS LTD. | 58 |
| Central Drug House(P) Ltd. | 58 |
| TCI Chemicals (India) Pvt. Ltd. | 58 |
| Otto Chemie Pvt. Ltd. | 58 |
| Maas Pharma Chemicals | 58 |
| Hebei Weibang Biotechnology Co., Ltd | 58 |
| Capot Chemical Co.,Ltd. | 60 |
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- Ribose (C5H10O5), with a molecular weight of 150.13 Dalton, is a pentose sugar comprising two enantiomers: L-ribose and D-ribo....
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