Deoxycytidine triphosphate trisodium salt

- CAS No.
- 109909-44-6
- Chemical Name:
- Deoxycytidine triphosphate trisodium salt
- Synonyms
- Dctp-Na3;dCTP,3Na;dCTP·3Na Solution;DCTP (SODIUM SALT);dCTP Sodium Salt Solution(100mM);2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE TRISODI;Deoxycytidine triphosphate trisodium salt;2'-DEOXYCYTIDINE 5'-TRIPHOSPHATE (SODIUM SALT);2'-Deoxycytidine-5'-triphosphate trisodium salt;Deoxycytidine-5'-Triphosphoric Acid Trisodium Sal
- CBNumber:
- CB0258120
- Molecular Formula:
- C9H17N3NaO13P3
- Molecular Weight:
- 491.15
- MOL File:
- 109909-44-6.mol
- MSDS File:
- SDS
- Modify Date:
- 2024/11/19 20:33:22
storage temp. | -20°C |
---|---|
solubility | Water: 10 mg/ml |
form | A crystalline solid |
color | Colorless to light yellow |
Water Solubility | Water: 10 mg/ml |
InChIKey | WBIPTAOOMJEGQO-JXXKLNQHNA-K |
SMILES | N1(C=CC(N)=NC1=O)[C@H]1C[C@H](O)[C@@H](COP([O-])(=O)OP([O-])(=O)OP([O-])(=O)O)O1.[Na+].[Na+].[Na+] |&1:8,10,12,r| |
CAS DataBase Reference | 109909-44-6(CAS DataBase Reference) |
Deoxycytidine triphosphate trisodium salt Chemical Properties,Uses,Production
Description
Deoxycytidine triphosphate trisodium salt (dCTP trisodium salt or 2′-Deoxycytidine-5′-triphosphate trisodium salt) is a nucleoside triphosphate that can be used for DNA synthesis. Deoxycytidine triphosphate trisodium salt has many applications, such as real-time PCR, cDNA synthesis, and DNA sequencing.
Uses
Deoxycytidine triphosphate trisodium salt (2′-Deoxycytidine-5′-triphosphate trisodium salt) is an activator that has been shown to exhibit anticancer and antiviral activities. It is a novel nucleoside phosphoramidite that is used in the synthesis of DNA, RNA, and other nucleic acids. 2′-Deoxycytidine-5′-triphosphate trisodium salt has been modified by substituting the oxygen atom for a sulfur atom at the 5' position of the sugar moiety. This change makes it resistant to degradation by ribonucleases. 2′-Deoxycytidine-5′-triphosphate trisodium salt has also been shown to act as an inhibitor of human telomerase activity.
in vitro
Assays of thirteen cell lines, derived from mouse lymphomas, myelomas, myeloid tumors, and a mastocytoma, for sensitivity to growth inhibition by 1-β-D-arabinofuranosylcytosine (ara-C) revealed a spectrum between the most and least sensitive which differed 100-fold from each other. An inverse correlation between sensitivity and cellular Deoxycytidine triphosphate (2′-Deoxycytidine-5′-triphosphate, dCTP) content is found, and this suggested that sensitivity of cells might be increased if the dCTP content was lowered during cell exposure to ara-C.
Deoxycytidine triphosphate trisodium salt is a phosphoethanolamine cytidylyltransferase substrate.
Deoxycytidine triphosphate trisodium salt Preparation Products And Raw materials
Raw materials
Preparation Products
Deoxycytidine triphosphate trisodium salt Suppliers
Supplier | Tel | Country | ProdList | Advantage | Inquiry |
---|---|---|---|---|---|
A.J Chemicals | 91-9810153283 | New Delhi, India | 6100 | 58 | Inquiry |
Jinan Carbotang Biotech Co.,Ltd. | +8615866703830 | China | 8497 | 58 | Inquiry |
BOC Sciences | +1-631-485-4226 | United States | 19552 | 58 | Inquiry |
CONIER CHEM AND PHARMA LIMITED | +8618523575427 | China | 49732 | 58 | Inquiry |
SIMAGCHEM CORP | +86-13806087780 | China | 17365 | 58 | Inquiry |
TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | United States | 32159 | 58 | Inquiry |
Career Henan Chemica Co | +86-0371-86658258 +8613203830695 | China | 30230 | 58 | Inquiry |
ANHUI WITOP BIOTECH CO., LTD | +8615255079626 | China | 23541 | 58 | Inquiry |
Dideu Industries Group Limited | +86-29-89586680 +86-15129568250 | China | 22854 | 58 | Inquiry |
NewCan Biotech Limited | +86-0571-86912261 +8613735419629 | China | 9985 | 58 | Inquiry |
Supplier | Advantage |
---|---|
A.J Chemicals | 58 |
Jinan Carbotang Biotech Co.,Ltd. | 58 |
BOC Sciences | 58 |
CONIER CHEM AND PHARMA LIMITED | 58 |
SIMAGCHEM CORP | 58 |
TargetMol Chemicals Inc. | 58 |
Career Henan Chemica Co | 58 |
ANHUI WITOP BIOTECH CO., LTD | 58 |
Dideu Industries Group Limited | 58 |
NewCan Biotech Limited | 58 |
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