N-Hydroxysertraline

N-Hydroxysertraline Structure
CAS No.
124345-07-9
Chemical Name:
N-Hydroxysertraline
Synonyms
N-Hydroxysertraline;Sertraline N-Hydroxy;N-Hydroxy Sertraline;*Buprenorphine Impurity 2 (Buprenorphine EP Impurity B);(1S-cis)-4-(3,4-Dichlorophenyl)-1,2,3,4-tetrahydro-N-hydroxy-N-Methyl-1-naphthalenaMine;1-Naphthalenamine, 4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-N-hydroxy-N-methyl-, (1S-cis)- (9CI)
CBNumber:
CB82622893
Molecular Formula:
C17H17Cl2NO
Molecular Weight:
322.22898
MOL File:
124345-07-9.mol
Modify Date:
2023/4/23 13:52:06

N-Hydroxysertraline Properties

Melting point 102 - 107°C
Boiling point 458.3±45.0 °C(Predicted)
Density 1.34±0.1 g/cm3(Predicted)
storage temp. -20°C Freezer, Under inert atmosphere
solubility DMSO (Slightly), Ethyl Acetate (Sparingly)
pka 13.17±0.40(Predicted)
form Solid
color White to Off-White

N-Hydroxysertraline Chemical Properties,Uses,Production

Uses

N-Hydroxy Sertraline is one of the major metabolite of Sertraline (S280000), a potent and selective inhibitor of neuronal serotonin uptake.

N-Hydroxysertraline Preparation Products And Raw materials

Raw materials

Preparation Products

(1S-cis)-4-(3,4-Dichlorophenyl)-1,2,3,4-tetrahydro-N-hydroxy-N-Methyl-1-naphthalenaMine N-Hydroxy Sertraline N-Hydroxysertraline Sertraline N-Hydroxy 1-Naphthalenamine, 4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-N-hydroxy-N-methyl-, (1S-cis)- (9CI) *Buprenorphine Impurity 2 (Buprenorphine EP Impurity B) 124345-07-9 Amines Aromatics Intermediates & Fine Chemicals Metabolites & Impurities Pharmaceuticals Amines, Aromatics, Metabolites & Impurities, Pharmaceuticals, Intermediates & Fine Chemicals