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Sertraline hydrochloride

Sertraline hydrochloride Structure
CAS No.
79559-97-0
Chemical Name:
Sertraline hydrochloride
Synonyms
SETRALINE HCL;SERTRALINE MANDELATE;Sertraline hydrochlo;Sertraline hydrochloride impurity standard;N-(4(3,4-DICHLOROPHENYL)-3,4-DIHYDRO-1(2H)NAPHTHALIDENE) METHANAMINE;(1S,4S)-4-(3,4-DICHLOROPHENYL)-1,2,3,4-TETRAHYDRO-N-METHYL-1-NAPHTHALENAMINE HYDROCHLORIDE;(1S,4S)-4-(3,4-Dichlorophenyl)-N-Methyl-1,2,3,4-tetrahydronaphthalen-1-aMine hydrochloride;CP-51974-1;(1s-cis)-lorid;CP-51974-1 HCl
CBNumber:
CB8157645
Molecular Formula:
C17H18Cl3N
Molecular Weight:
342.69
MOL File:
79559-97-0.mol
MSDS File:
SDS
Modify Date:
2023/11/21 14:17:24

Sertraline hydrochloride Properties

Melting point 246-249°C
alpha D23 +37.9° (c = 2 in methanol)
Density 1.37
Flash point 9℃
storage temp. 2-8°C
solubility DMSO: ~26 mg/mL
form solid
pka pKa (water): 9.48 ± 0.04; pKa (methanol:water, 40:60 v/v): 8.6; pKa (ethanol:water, 1:1 v/v): 8.5(at 25℃)
color white
Merck 14,8467
Stability Store in Freezer
CAS DataBase Reference 79559-97-0(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07,GHS09
Signal word  Warning
Hazard statements  H302-H400
Precautionary statements  P273-P301+P312+P330
Hazard Codes  Xi,T,F
Risk Statements  36/37/38-39/23/24/25-23/24/25-11
Safety Statements  22-24/25-36-26-45-36/37-16-7
RIDADR  UN1230 - class 3 - PG 2 - Methanol, solution
WGK Germany  3
RTECS  QJ0352070
HazardClass  IRRITANT
HS Code  29214990
NFPA 704
0
2 0

Sertraline hydrochloride price More Price(6)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) S6319 Sertraline hydrochloride ≥98% (HPLC) 79559-97-0 10MG ₹14224.05 2022-06-14 Buy
Sigma-Aldrich(India) S6319 Sertraline hydrochloride ≥98% (HPLC) 79559-97-0 50MG ₹63802.55 2022-06-14 Buy
Sigma-Aldrich(India) S-021 Sertraline hydrochloride solution 1.0?mg/mL in methanol (as free base), ampule of 1?mL, certified reference material, Cerilliant? 79559-97-0 1ML ₹4708.2 2022-06-14 Buy
Sigma-Aldrich(India) PHR2535 Sertraline hydrochloride Pharmaceutical Secondary Standard; Certified Reference Material 79559-97-0 200MG ₹39792.7 2022-06-14 Buy
TCI Chemicals (India) S0507 Sertraline Hydrochloride 79559-97-0 1G ₹6100 2022-05-26 Buy
Product number Packaging Price Buy
S6319 10MG ₹14224.05 Buy
S6319 50MG ₹63802.55 Buy
S-021 1ML ₹4708.2 Buy
PHR2535 200MG ₹39792.7 Buy
S0507 1G ₹6100 Buy

Sertraline hydrochloride Chemical Properties,Uses,Production

Description

Sertraline hydrochloride is a selective serotonin reuptake inhibitor, similar mechanistically to fluoxetine, introduced initially for the maintenance and long-term treatment of depression. It is reportedly non-sedating and compared to fluoxetine has a shorter duration of action and lack of CNS activating effects such as nervousness and anxiety. Sertraline hydrochloride is currently undergoing investigation for the treatment of obesity and obsessive-compulsive disorders.

Chemical Properties

White or almost white, crystalline powder.

Uses

The effect of exposure of sertraline hydrochloride was studied in chronically prepared ovine fetus. It was used in glucocorticoid function assay to study the effect of antidepressants on glucocorticoid receptor function in humans.

Definition

ChEBI: A hydrochloride resulting from the reaction of equimolar amounts of sertraline and hydrogen chloride. A selective serotonin-reuptake inhibitor (SSRI), it is administered orally as an antidepressant for the treatment of depression, obsessive-compulsive diso der, panic disorder and post-traumatic stress disorder.

General Description

Sertraline, marketed as the brand drug Zoloft?, is an SSRI antidepressant used in the treatment of major depression as well as obsessive-compulsive, panic, and social anxiety disorders. This Certified Snap-N-Spike? Solution is applicable for use in LC/MS or GC/MS applications for urine drug testing, clinical toxicology, and forensic analysis.

Biological Activity

Potent, orally active selective serotonin re-uptake inhibitor (SSRI) used clinically to treat depression.

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Sertraline hydrochloride Spectrum

(1S,4S)-4-(3,4-DICHLOROPHENYL)-1,2,3,4-TETRAHYDRO-N-METHYL-1-NAPTHALENAMINE HYDROCHLORIDE (1S,4S)-1-(3,4-DICHLOROPHENYL)-1,2,3,4-TETRAHYDRO-4-(METHYLAMINO)NAPHTHALENE HYDROCHLORIDE SERTRALINE HCL FORM I SERTRALINE HCL FORM II SERTRALINE HYDROCHLORIDE Rac-cis-Sertraline-13C-d3 HCl 1-NaphthalenaMine,4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-N-Methyl-, hydrochloride (1:1),(1S,4S)- CP-51974-1 HCl Sertraline hydrochloride solution (1s-cis)-lorid 4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-n-methyl-1-naphthalenaminhydroch Sertralinumhydrochloride 1-Naphthalenamine, 4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-N-methyl-, hydrochloride, (1S,4S)- Sertaline hydrochloride (1S,4S)-4-(3,4-Dichlorophenyl)-1,2,3,4-tetrahydro-N-methyl-1-naphthylamine hydrochloride CP-51974-1 Lustral:Zoloft Sertraline hydrochloride,(1S,4S)-4-(3,4-Dichlorophenyl)-1,2,3,4-tetrahydro-N-methyl-1-naphthalenamine hydrochloride Sertraline Hydrochloride (100 mg) (1S-cis)-4-(3,4-Dichlorophenyl)-1,2,3,4-tetrahydro-N-methyl-1-naphthalenamine hydrochloride Sertraline hydrochloride, 98%, an antidepressant of the selective serotonin reuptake inhibitor (SSRI) (1S,4S)-4-(3,4-Dichlorophenyl)-1-(methylamino)-1,2,3,4-tetrahydronaphthalene Hydrochloride [4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-1-naphthalenyl]methylamine hydrochloride Sertraline Hydrochloride D3 SertralineHydrochloride> Sertraline hydrochloride CRS (+)-(1S,4S)-Sertraline hydrochloride Sertraline hydrochloride USP/EP/BP Sertraline Hydrochloride (1.0 mg/mL in Methanol) Hydrochloride Salt of Sertraline (1S,4S)-4-(3,4-Dichlorophenyl)-1,2,3,4-tetrahydro-N-methyl-1-napthalenamine Sertraline Hydrochloride Powder CAS 79559-97-0 Sertraline HCl Sertraline for peak identification (Y0000866) Sertraline for system suitability(Y0000867) Sertraline hydrochloride (Y0000828)Q: What is Sertraline hydrochloride (Y0000828) Q: What is the CAS Number of Sertraline hydrochloride (Y0000828) Q: What are the applications of Sertraline hydrochloride (Y0000828) CAS 79559-97-0 Sertraline hydrochloride Sertraline Hydrochloride (1612539) (1S,4S)-4-(3,4-DICHLOROPHENYL)-1,2,3,4-TETRAHYDRO-N-METHYL-1-NAPHTHALENAMINE HYDROCHLORIDE SERTRALINE MANDELATE SETRALINE HCL N-(4(3,4-DICHLOROPHENYL)-3,4-DIHYDRO-1(2H)NAPHTHALIDENE) METHANAMINE Sertraline hydrochlo (1S,4S)-4-(3,4-Dichlorophenyl)-N-Methyl-1,2,3,4-tetrahydronaphthalen-1-aMine hydrochloride Sertraline hydrochloride impurity standard 13C6]-Sertraline HCI Sertraline salt 79559-97-0 79559-07-0 C17H17Cl2NHCl C17H17Cl2NClH C17H17NCl2HCl C1717Cl2NHCl C18H18Cl2N KETEK Active Pharmaceutical Ingredients Pharmaceutical Intermediates APIs Inhibitors