Sertraline hydrochloride
- CAS No.
- 79559-97-0
- Chemical Name:
- Sertraline hydrochloride
- Synonyms
- SETRALINE HCL;SERTRALINE MANDELATE;Sertraline hydrochlo;Sertraline hydrochloride impurity standard;N-(4(3,4-DICHLOROPHENYL)-3,4-DIHYDRO-1(2H)NAPHTHALIDENE) METHANAMINE;(1S,4S)-4-(3,4-DICHLOROPHENYL)-1,2,3,4-TETRAHYDRO-N-METHYL-1-NAPHTHALENAMINE HYDROCHLORIDE;(1S,4S)-4-(3,4-Dichlorophenyl)-N-Methyl-1,2,3,4-tetrahydronaphthalen-1-aMine hydrochloride;CP-51974-1;(1s-cis)-lorid;CP-51974-1 HCl
- CBNumber:
- CB8157645
- Molecular Formula:
- C17H18Cl3N
- Molecular Weight:
- 342.69
- MOL File:
- 79559-97-0.mol
- MSDS File:
- SDS
- Modify Date:
- 2023/11/21 14:17:24
Melting point | 246-249°C |
---|---|
alpha | D23 +37.9° (c = 2 in methanol) |
Density | 1.37 |
Flash point | 9℃ |
storage temp. | 2-8°C |
solubility | DMSO: ~26 mg/mL |
form | solid |
pka | pKa (water): 9.48 ± 0.04; pKa (methanol:water, 40:60 v/v): 8.6; pKa (ethanol:water, 1:1 v/v): 8.5(at 25℃) |
color | white |
Merck | 14,8467 |
Stability | Store in Freezer |
CAS DataBase Reference | 79559-97-0(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
Symbol(GHS) | GHS07,GHS09 |
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Signal word | Warning | |||||||||
Hazard statements | H302-H400 | |||||||||
Precautionary statements | P273-P301+P312+P330 | |||||||||
Hazard Codes | Xi,T,F | |||||||||
Risk Statements | 36/37/38-39/23/24/25-23/24/25-11 | |||||||||
Safety Statements | 22-24/25-36-26-45-36/37-16-7 | |||||||||
RIDADR | UN1230 - class 3 - PG 2 - Methanol, solution | |||||||||
WGK Germany | 3 | |||||||||
RTECS | QJ0352070 | |||||||||
HazardClass | IRRITANT | |||||||||
HS Code | 29214990 | |||||||||
NFPA 704 |
|
Sertraline hydrochloride price More Price(6)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich(India) | S6319 | Sertraline hydrochloride ≥98% (HPLC) | 79559-97-0 | 10MG | ₹14224.05 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | S6319 | Sertraline hydrochloride ≥98% (HPLC) | 79559-97-0 | 50MG | ₹63802.55 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | S-021 | Sertraline hydrochloride solution 1.0?mg/mL in methanol (as free base), ampule of 1?mL, certified reference material, Cerilliant? | 79559-97-0 | 1ML | ₹4708.2 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | PHR2535 | Sertraline hydrochloride Pharmaceutical Secondary Standard; Certified Reference Material | 79559-97-0 | 200MG | ₹39792.7 | 2022-06-14 | Buy |
TCI Chemicals (India) | S0507 | Sertraline Hydrochloride | 79559-97-0 | 1G | ₹6100 | 2022-05-26 | Buy |
Sertraline hydrochloride Chemical Properties,Uses,Production
Description
Sertraline hydrochloride is a selective serotonin reuptake inhibitor, similar mechanistically to fluoxetine, introduced initially for the maintenance and long-term treatment of depression. It is reportedly non-sedating and compared to fluoxetine has a shorter duration of action and lack of CNS activating effects such as nervousness and anxiety. Sertraline hydrochloride is currently undergoing investigation for the treatment of obesity and obsessive-compulsive disorders.
Chemical Properties
White or almost white, crystalline powder.
Uses
The effect of exposure of sertraline hydrochloride was studied in chronically prepared ovine fetus. It was used in glucocorticoid function assay to study the effect of antidepressants on glucocorticoid receptor function in humans.
Definition
ChEBI: A hydrochloride resulting from the reaction of equimolar amounts of sertraline and hydrogen chloride. A selective serotonin-reuptake inhibitor (SSRI), it is administered orally as an antidepressant for the treatment of depression, obsessive-compulsive diso der, panic disorder and post-traumatic stress disorder.
General Description
Sertraline, marketed as the brand drug Zoloft?, is an SSRI antidepressant used in the treatment of major depression as well as obsessive-compulsive, panic, and social anxiety disorders. This Certified Snap-N-Spike? Solution is applicable for use in LC/MS or GC/MS applications for urine drug testing, clinical toxicology, and forensic analysis.
Biological Activity
Potent, orally active selective serotonin re-uptake inhibitor (SSRI) used clinically to treat depression.
Sertraline hydrochloride Preparation Products And Raw materials
Raw materials
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Basic Pharma Life Science Pvt Ltd | +919825056886 | Gujarat, India | 28 | 58 | Inquiry |
Lee Pharma Ltd | +91-9849085929 +91-9849085929 | Hyderabad, India | 42 | 58 | Inquiry |
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KRS Pharmaceuticals Pvt. Ltd. | +91-4023176686 +91-9848996298 | Hyderabad, India | 36 | 58 | Inquiry |
Nosch Labs Pvt Ltd | +91-4048557474 +91-9948222287 | Hyderabad, India | 58 | 58 | Inquiry |
Verdant Life Sciences Pvt Ltd | +91-9052522203 +91-9959142565 | Telangana, India | 13 | 58 | Inquiry |
Lakshmi Farmachem | +91-9948795885 +91-9550886476 | Telangana, India | 407 | 58 | Inquiry |
DSN Labs | +91-4027152282 +91-9491052860 | Telangana, India | 30 | 58 | Inquiry |
Lofty labs | +91-7673920392 +91-7673920392 | Telangana, India | 32 | 58 | Inquiry |
Supplier | Advantage |
---|---|
Basic Pharma Life Science Pvt Ltd | 58 |
Lee Pharma Ltd | 58 |
Hetero Drugs Limited | 58 |
Sun Pharmaceutical Industries Ltd | 58 |
KRS Pharmaceuticals Pvt. Ltd. | 58 |
Nosch Labs Pvt Ltd | 58 |
Verdant Life Sciences Pvt Ltd | 58 |
Lakshmi Farmachem | 58 |
DSN Labs | 58 |
Lofty labs | 58 |
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