Sertraline hydrochloride Chemische Eigenschaften,Einsatz,Produktion Methoden
R-Sätze Betriebsanweisung:
R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.
S-Sätze Betriebsanweisung:
S22:Staub nicht einatmen.
S24/25:Berührung mit den Augen und der Haut vermeiden.
S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
Beschreibung
Sertraline hydrochloride is a selective serotonin reuptake inhibitor, similar mechanistically
to fluoxetine, introduced initially for the maintenance and long-term treatment of
depression. It is reportedly non-sedating and compared to fluoxetine has a shorter duration
of action and lack of CNS activating effects such as nervousness and anxiety. Sertraline
hydrochloride is currently undergoing investigation for the treatment of obesity and
obsessive-compulsive disorders.
Chemische Eigenschaften
White or almost white, crystalline powder.
Verwenden
The effect of exposure of sertraline hydrochloride was studied in chronically prepared ovine fetus. It was used in glucocorticoid function assay to study the effect of antidepressants on glucocorticoid receptor function in humans.
Definition
ChEBI: A hydrochloride resulting from the reaction of equimolar amounts of sertraline and hydrogen chloride. A selective serotonin-reuptake inhibitor (SSRI), it is administered orally as an antidepressant for the treatment of depression, obsessive-compulsive diso
der, panic disorder and post-traumatic stress disorder.
Allgemeine Beschreibung
Sertraline, marketed as the brand drug Zoloft
, is an SSRI antidepressant used in the treatment of major depression as well as obsessive-compulsive, panic, and social anxiety disorders. This Certified Snap-N-Spike
Solution is applicable for use in LC/MS or GC/MS applications for urine drug testing, clinical toxicology, and forensic analysis.
Biologische Aktivität
Potent, orally active selective serotonin re-uptake inhibitor (SSRI) used clinically to treat depression.
Sertraline hydrochloride Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
