Mandelic acid
- CAS No.
- 611-71-2
- Chemical Name:
- Mandelic acid
- Synonyms
- D-MANDELIC ACID;(R)-(-)-MANDELIC ACID;(R)-2-HYDROXY-2-PHENYLACETIC ACID;(R)-MANDELIC ACID;2-Hydroxy-2-phenylacetic acid;(R)-(-)-2-MANDELIC ACID;(-)-MANDELIC ACID;D-(-)-MANDELIC ACID;(-)-D-MANDELIC ACID;D-ALPHA-HYDROXYPHENYLACETIC ACID
- CBNumber:
- CB9411418
- Molecular Formula:
- C8H8O3
- Molecular Weight:
- 152.15
- MOL File:
- 611-71-2.mol
- MSDS File:
- SDS
- Modify Date:
- 2024/8/21 22:41:43
| Melting point | 131-133 °C(lit.) |
|---|---|
| alpha | -150 º (c=2.5, H2O) |
| Boiling point | 214.6°C (rough estimate) |
| Density | 1.1677 (rough estimate) |
| refractive index | -153.5 ° (C=1, H2O) |
| Flash point | >190℃ |
| storage temp. | Store below +30°C. |
| solubility | 109.8g/l soluble |
| form | Crystalline Powder, Crystals or Flakes |
| pka | 3.37(at 25℃) |
| color | White to slightly yellow-beige |
| PH | 3.34(1 mM solution);2.75(10 mM solution);2.22(100 mM solution); |
| optical activity | [α]25/D 151°, c = 1 in ethanol |
| Water Solubility | It is partly soluble in water, freely soluble in isopropyl and ethyl alcohol. |
| Sensitive | Light Sensitive |
| BRN | 2691094 |
| Stability | Stable, but light sensitive. Combustible. Incompatible with strong bases, strong oxidizing agents. |
| InChIKey | IWYDHOAUDWTVEP-SSDOTTSWSA-N |
| LogP | 0.550 (est) |
| CAS DataBase Reference | 611-71-2(CAS DataBase Reference) |
| EPA Substance Registry System | Benzeneacetic acid, .alpha.-hydroxy-, (.alpha.R)- (611-71-2) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS05 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H318 | |||||||||
| Precautionary statements | P280-P305+P351+P338 | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 41-36/37/38 | |||||||||
| Safety Statements | 22-24/25-36-26-39-37/39 | |||||||||
| WGK Germany | 1 | |||||||||
| Hazard Note | Irritant/Light Sensitive | |||||||||
| TSCA | Yes | |||||||||
| HS Code | 29181980 | |||||||||
| Toxicity | LD50 orally in Rabbit: 5000 mg/kg | |||||||||
| NFPA 704 |
|
Mandelic acid price More Price(21)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | M2209 | (R)-(−)-Mandelic acid 98% | 611-71-2 | 25G | ₹4654.75 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | 8.06914 | (R)-(-)-Mandelic acid for resolution of racemates for synthesis | 611-71-2 | 25G | ₹10480 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | 727075 | (R)-(−)-Mandelic acid ChiPros?, produced by BASF, 99% | 611-71-2 | 25G | ₹4438.25 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | 8.06914 | (R)-(-)-Mandelic acid for resolution of racemates for synthesis | 611-71-2 | 100G | ₹16419.99 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | 727075 | (R)-(−)-Mandelic acid ChiPros?, produced by BASF, 99% | 611-71-2 | 100G | ₹12167.3 | 2022-06-14 | Buy |
Mandelic acid Chemical Properties,Uses,Production
Chemical Properties
white to light yellow crystal powde
Uses
(R)-(-)-Mandelic acid, is used as a antiseptic ingredient particularly against urinary tract infections.Mandelic acid and its derivatives are used to apply the dual activities as an antibacterial agent and as an antiaging agent. It is used as an intermediate for the synthesis of target molecules for other applications.
General Description
(R)-(-)-Mandelic acid, a chiral resolving agent, is also used as a building block to synthesize pharmaceutical drugs such as penicillin and cephalosporin. It can be synthesized from (R,S)-mandelonitrile with high yield and enantioselectivity using nitrilase enzyme.
Purification Methods
Purify the mandelic acids by recrystallisation from H2O, *C6H6 or CHCl3. [Roger J Chem Soc 2168 1932,Jamison & Turner J Chem Soc 611 1942.] They have solubilities in H2O of ca 11% at 25o. [Banks & Davies J Chem Soc 73 1938.] The S-benzylisothiuronium salts has m 180o (from H2O) and [] D 25 (+) and (-) 57o (c20, EtOH) [El Masri et al. Biochem J 68 199 1958]. [Beilstein 10 IV 564.]
Mandelic acid Preparation Products And Raw materials
Raw materials
Preparation Products
1H-Azepine-4-carboxylicacid,hexahydro-,methylester,(4R)-(9CI)
(R)-3-Amino-1-(3-(Trifluoromethyl)-5,6-Dihydro-[1,2,4] Triazolo[4,3-A]Pyrazin-7(8H)-Yl)-4-(2,4,5-Trifluorophenyl) Butan-1-One Mandelate(Sgn06M)
(R)-5-phenyl-1,3-dioxolane-2,4-dione
(R)-2-Hydroxy-2-phenylacetohydrazide
(R)-2-tert-butyl-3-Methyl-4-oxoiMidazolidin-1-iuM (R)-2-hydroxy-2-phenylacetate
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Global( 747)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| Bhausa Life Sciences | +91-8154986830 +91-8154986830 | Gujarat, India | 201 | 58 | Inquiry |
| GLP Pharma Standards | +91 9866074638 | Hyderabad, India | 1644 | 58 | Inquiry |
| JSK Chemicals | +919879767970 | Gujarat, India | 3756 | 58 | Inquiry |
| BASF India Limited | +91-2262785600 +91-2262785600 | Maharashtra, India | 209 | 58 | Inquiry |
| R L Chemical Industries Pvt Ltd | +91-9987934087 +91-9987934087 | Mumbai, India | 12 | 58 | Inquiry |
| Neogen Chemicals Ltd | +91-9619496467 +91-8657984687 | Maharashtra, India | 56 | 58 | Inquiry |
| S D Fine Chem Limited | +91-9323715856 +91-9323715856 | Maharashtra, India | 368 | 58 | Inquiry |
| Molsyns Research | +91-9586858886 +91-9586858886 | Gujarat, India | 418 | 58 | Inquiry |
| Allmpus Laboratories Pvt Ltd | +91-9518738415 +91-9167862134 | Maharashtra, India | 657 | 58 | Inquiry |
| CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6351 | 58 | Inquiry |
| Supplier | Advantage |
|---|---|
| Bhausa Life Sciences | 58 |
| GLP Pharma Standards | 58 |
| JSK Chemicals | 58 |
| BASF India Limited | 58 |
| R L Chemical Industries Pvt Ltd | 58 |
| Neogen Chemicals Ltd | 58 |
| S D Fine Chem Limited | 58 |
| Molsyns Research | 58 |
| Allmpus Laboratories Pvt Ltd | 58 |
| CLEARSYNTH LABS LTD. | 58 |
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- Mar 10，2022
611-71-2(Mandelic acid)Related Search:
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(R)-(-)-2-MANDELIC ACID
(R)-2-HYDROXY-2-PHENYLACETIC ACID
(R)-(-)-AMYGDALIC ACID
(R)-ALPHA-HYDROXYPHENYLACETIC ACID
R-(-)-ALPHA-HYDROXYPHENYLACETIC ACID
(R)-(-)-MANDELIC ACID
(R)-MANDELIC ACID
D-ALPHA-HYDROXYPHENYLACETIC ACID
D-A-HYDROXYPHENYLACETIC ACID
D-2-HYDROXY-PHENYLACETIC ACID
D-(-)-AMYGDALIC ACID
D-AMYGDALIC ACID
D-PHENYLGLYCOLIC ACID
(-)-D-MANDELIC ACID
D-(-)-MANDELIC ACID
D-MANDELIC ACID
L-2-hydroxy-2-phenylacetic acid
D(-)-MANDELIC ACID FOR RESOLUTION &
(R)-(-)-MANDELIC ACID, 99+%
(R)-(-)-MANDELIC ACID, 98% (99% EE/GLC)
(R)-(-)-MANDELIC ACID 99%
D-(-)-α-Hydroxybenzeneacetic acid
ALPHAR-HYDROXY-BENZENEACETIC ACID
(-)-MANDELIC ACID
D-Mandelic acid or R-(-)Mandelic acid
Benzeneacetic acid, .alpha.-hydroxy-, (.alpha.R)-
(r)-(-)-à-hydroxyphenylacetic acid
D-mandelic acid(R-mandelic acid)
(R)-alpha-Hydrophenylacetic acid
D-(-)-Mandelic acid 98%
L-2-Hydroxy-2-phenylessigsure
D-minus-mandelic acid sigma grade
[R,(-)]-α-Hydroxybenzeneacetic acid
D-()-Mandelic acid,(R)-α-Hydroxyphenylacetic acid
(R)-(-)-Mandelic acid, ChiPros\(tm, 99+% ee 99+%
)-Mandel
(R)-(-)-alpha-Hydroxyphenylacetic acid, (2R)-(-)-Hydroxy(phenyl)ethanoic acid, D-(-)-Phenylglycolic acid
(R)-Alfa-hydroxyphenylacetic acid
(R)-()-Mandel
(R)-(-)-Mandelic acid, 99% 25GR
(R)-(-)-Mandelic acid, 98% e.e.
(R)-(-)-MANDELIC ACID FOR RESOLUTION OF
(R)-2-Phenylglycolic acid
(R)-alpha-Hydroxy-benzeneacetic acid
Sertraline EP IMpurity E
(R)-(-)-alpha-Hydroxyphenylacetic acid, (2R)-(-)-2-Hydroxy-2-phenylethanoic acid, D-(-)-Phenylglycolic acid
(R)-(-)-Mandelic acid, ChiPros 99+%, ee 99+%
D-MANDELIC ACID extrapure
(2R)-2-Hydroxy-2-phenylacetic acid
(R)-a-Hydroxybenzeneacetic acid
(R)-a-Hydroxyphenylacetic acid
D-2-Phenylglycolic acid
(R)-(-)-MANDELIC ACID: CHIPROS 99%, EE 99%
2-Hydroxy-2-phenylacetic acid
2-Phenylglycolic acid
a-Hydroxy-benzeneacetic acid
alpha-Hydroxyphenylacetic acid
Hydroxy(phenyl)acetic acid