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D-Luciferin

D-Luciferin Structure
CAS No.
2591-17-5
Chemical Name:
D-Luciferin
Synonyms
uciferin;LUCIFERIN;D-LUCIFERIN;D-Leciferin;LUCIFERIN, D-;D(-)-LUCIFERIN;AURORA KA-6717;BEETLE LUCIFERIN;FIREFLY LUCIFERIN;Photinus luciferin
CBNumber:
CB8283216
Molecular Formula:
C11H8N2O3S2
Molecular Weight:
280.32
MOL File:
2591-17-5.mol
MSDS File:
SDS
Modify Date:
2024/3/8 15:03:12

D-Luciferin Properties

Melting point 200-204 °C
alpha D22 -36° (c = 1.2 in DMF)
Boiling point 587.6±60.0 °C(Predicted)
Density 1.4916 (rough estimate)
refractive index 1.5650 (estimate)
storage temp. -20°C
solubility DMF:30.0(Max Conc. mg/mL);107.02(Max Conc. mM)
DMSO:35.33(Max Conc. mg/mL);126.05(Max Conc. mM)
pka 8.31±0.40(Predicted)
form Powder
color Off-white to light yellow
λmax 360nm(H2O)(lit.)
Merck 14,4086
BRN 30484
InChI InChI=1S/C11H8N2O3S2/c14-5-1-2-6-8(3-5)18-10(12-6)9-13-7(4-17-9)11(15)16/h1-3,7,14H,4H2,(H,15,16)/t7-/m1/s1
InChIKey BJGNCJDXODQBOB-SSDOTTSWSA-N
SMILES S1C[C@H](C(O)=O)N=C1C1=NC2=CC=C(O)C=C2S1

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P271-P280
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-36/37/39-24/25
WGK Germany  3
8-10
HS Code  29342000

D-Luciferin price More Price(11)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) L9504 D-Luciferin synthetic 2591-17-5 1MG ₹6094.48 2022-06-14 Buy
Sigma-Aldrich(India) L9504 D-Luciferin synthetic 2591-17-5 5MG ₹19885.53 2022-06-14 Buy
Sigma-Aldrich(India) L9504 D-Luciferin synthetic 2591-17-5 10MG ₹33470.9 2022-06-14 Buy
Sigma-Aldrich(India) L9504 D-Luciferin synthetic 2591-17-5 50MG ₹131556.23 2022-06-14 Buy
Sigma-Aldrich(India) L9504 D-Luciferin synthetic 2591-17-5 100MG ₹196159.83 2022-06-14 Buy
Product number Packaging Price Buy
L9504 1MG ₹6094.48 Buy
L9504 5MG ₹19885.53 Buy
L9504 10MG ₹33470.9 Buy
L9504 50MG ₹131556.23 Buy
L9504 100MG ₹196159.83 Buy

D-Luciferin Chemical Properties,Uses,Production

Description

D-Luciferin is a popular bioluminescent substrate of luciferase in the presence of ATP, used in luciferase-based bioluminescence imaging and cell-based high-throughput screening applications. In an immunocompetent mouse model of ovarian cancer, the use of D-luciferin substrate and firefly luciferase preserves tumour-host immune interactions since bioluminescent imaging is a more sensitive indication of tumour growth than weight gain.

Chemical Properties

off-white to light yellow powder

Uses

D-Luciferin has been used in determining luciferase activity by luciferase assay in mice and Arabidopsis thaliana seeds. It has also been used in measuring bioluminescence in neonatal rat ventricular cardiomyocytes.

Definition

ChEBI: A 1,3-thiazolemonocarboxylic acid consisting of 3,5-dihydrothiophene-4-carboxylic acid having a 6-hydroxybenzothiazol-2-yl group at the 2-position.

General Description

D-Luciferin is a small molecule present abundantly in bioluminescent organisms. This molecule is sensitive to oxygen and light.

Purification Methods

D-Luciferin crystallises as pale yellow needles from H2O, or MeOH (83mg/7mL). It has UV max at 263 and 327nm (log 3.88 and 4.27) in 95% EtOH. The Na salt has a solubility of 4mg in 1 mL of 0.05M glycine. [White et al. J Am Chem Soc 83 2402 1961, 85 337 1963, UV and IR: Bitler & McElroy Arch Biochem 72 358 1957, Review: Cormier et al. Fortschr Chem Org Naturst 30 1 1973, Beilstein 27 III/IV 8934.]

D-Luciferin Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 336)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
Inventichem +918790275459 Telangana, India 155 58 Inquiry
CLEARSYNTH LABS LTD. +91-22-45045900 Hyderabad, India 6351 58 Inquiry
CHEMSWORTH +91-261-2397244 New Delhi, India 6707 30 Inquiry
A.J Chemicals 91-9810153283 New Delhi, India 6124 58 Inquiry
TCI Chemicals (India) Pvt. Ltd. 1800 425 7889 New Delhi, India 6778 58 Inquiry
Sisco Research Laboratories Pvt. Ltd. +91-22-4268 5800 Mumbai, India 4317 58 Inquiry
Maas Pharma Chemicals +91-9958666224 Delhi, India 1607 58 Inquiry
Biopharmacule Speciality Chemicals P Ltd (India) +91 40 6462 1866 Hyderabad, India 526 58 Inquiry
Triveni chemicals 08048762458 New Delhi, India 6093 58 Inquiry
Hersimran Furnishers Private Limited 09958684181 Delhi, India 1 58 Inquiry

D-Luciferin Spectrum

4,5-DIHYDRO-2-(6-HYDROXY-2-BENZOTHIAZOLYL)-4-THIAZOLECARBOXY 4,5-DIHYDRO-2-[6-HYDROXY-2-BENZOTHIAZOLYL]-4-THIAZOLE-CARBOXYLIC ACID 4,5-DIHYDRO-(6-HYDROXY-2-BENZOTHIAZOYL)-4-THIAZOLE CARBOXYLIC ACID LUCIFERIN, D- LUCIFERIN D(-)-2-(6'-HYDROXY-BENZOTHIAZOLYL)-DELTA2-THIAZOLINE-4-CARBOXYLIC ACID D(-)-LUCIFERIN D-LUCIFERIN D-LUCIFERIN FIREFLY D-Luciferin≥ 99% (HPLC) Photinus luciferin (S)-4,5-Dihydro-2-(6-hydroxy-2-benzothiazolyl)-4 thiazolecarboxylic acid (4S)-2-(6-Hydroxy-1,3-benzothiazol-2-yl)-4,5-dihydrothiazole-4-carboxylic acid FIREFLY LUCIFERIN BEETLE LUCIFERIN AURORA KA-6717 (S)-2-[6-HYDROXY-2-BENZOTHIAZOLYL]-2-THIAZOLENE-4 (S)-2-(6-HYDROXY-2-BENZOTHIAZOLYL)-2-THIAZOLINE-4-CARBOXYLIC ACID (S)-4,5-dihydro-2-(6-hydroxybenzothiazol-2-yl)thiazole-4-carboxylic acid D-Luciferin free acid, 99% D-LUCIFERIN SYNTHETIC D-LUCIFERIN SIGMAULTRA D -LUCIFERIN SYNTHETIC CRYSTALLINE Beetle luciferin Firefly luciferin D-LUCIFERIN,FREEACID,ULTRAPURE D-Leciferin (4S)-2-(6-hydroxy-1,3-benzothiazol-2-yl)-4,5-dihydro-1,3-thiazole-4-carboxylic acid D-(-)-Luciferin  (D)-4,5-Dihydro-2-(6-hydroxy-2-benzothiazolyl)-4-thiazolecarboxylic acid, Firefly (synthetic), 99% D-LUCIFERINFREEACID,99% D-Luciferin, Free acid >99.5% 2-(6-Hydroxy-benzothiazol-2-yl)-thiazole-4-carboxylic acid D-Luciferin Firefly Luciferin, (S)-2-(6-Hydroxy-2-benzothiazolyl)-2-thiazoline-4-carboxylic acid, 4,5-Dihydro-2-(6-hydroxy-2-benzothiazolyl)-4-thiazolecarboxylic acid (4S)-2-(6-Hydroxy-2-benzothiazolyl)-2-thiazoline-4β-carboxylic acid (4S)-2-(6-Hydroxybenzothiazole-2-yl)-2-thiazoline-4-carboxylic acid D-(-)-Luciferin [Chemiluminescence Reagent] (4S)-4,5-Dihydro-(6-hydroxy-2-benzothiazoyl)-4-thiazolecarboxylic acid (S)-2-(6-hydroxybenzo[d]thiazol-2-yl)-4,5-dihydrothiazole-4-carboxylic acid D-Luciferin, free acid *CAS#: 2591-17-5* Luciferin, D- - Firefly Luciferin 2-(6-oxo-1,3-benzothiazol-2-ylidene)-4-thiazolidinecarboxylic acid D-(-)-Luciferin [Chemiluminescence Reagent]> uciferin 4-Thiazolecarboxylic acid, 4,5-dihydro-2-(6-hydroxy-2-benzothiazolyl)-, (4S)- D-luciferin (Firefly luciferin) D-Luciferin ex. Firefly, 99% 7-Dihydroxyflavone D-Luciferin Firefly, Free Acid 2591-17-5 2951-17-5 C11H7FN2O3S2 Biochemicals and Reagents Analytical Enzymes BioChemical Enzymes, Inhibitors, and Substrates Detection Fluorescent Probes, Labels, Particles and Stains Luciferase