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4,4'-(4H-1,2,4-TRIAZOL-4-YLMETHYLENE)BIS BENZONITRILE

4,4'-(4H-1,2,4-TRIAZOL-4-YLMETHYLENE)BIS BENZONITRILE Structure
CAS No.
112809-52-6
Chemical Name:
4,4'-(4H-1,2,4-TRIAZOL-4-YLMETHYLENE)BIS BENZONITRILE
Synonyms
dibenzonitrile;Iso Letrozole;AMiodarone IMpurity-B;AMiodarone IMpurity-A;Letrozole EP Impurity A;Letrozole USP iMpurities;Letrozole USP Impurity A;Letrozole Related CoMpound A;LETRAZOLE REALTED COMPOUND A;4,4'-((4H-1,2,4-Triazol-4-yl)
CBNumber:
CB8329754
Molecular Formula:
C17H11N5
Molecular Weight:
285.3
MOL File:
112809-52-6.mol
Modify Date:
2023/4/23 13:52:06

4,4'-(4H-1,2,4-TRIAZOL-4-YLMETHYLENE)BIS BENZONITRILE Properties

Melting point 239-243 °C
Boiling point 563.5±60.0 °C(Predicted)
Density 1.21±0.1 g/cm3(Predicted)
storage temp. 2-8°C
solubility Chloroform (Slightly, Heated), Methanol (Slightly)
form Solid
pka 2.48±0.10(Predicted)
color Off-White to Pale Yellow

SAFETY

Risk and Safety Statements

HS Code  2933998350

4,4'-(4H-1,2,4-TRIAZOL-4-YLMETHYLENE)BIS BENZONITRILE Chemical Properties,Uses,Production

Uses

Isoletrozole is an impurity of Letrozole (L330100). Letrozole impurity A as per USP.

4,4'-(4H-1,2,4-TRIAZOL-4-YLMETHYLENE)BIS BENZONITRILE Preparation Products And Raw materials

Raw materials

Preparation Products

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4,4'-(4H-1,2,4-TRIAZOL-4-YLMETHYLENE)BIS BENZONITRILE Iso Letrozole Letrozole USP iMpurities AMiodarone IMpurity-A AMiodarone IMpurity-B 4,4'-(1H-1,3,4-triazol-1-ylMethylene)dibenzonitrile Letrozole Related CoMpound A 4,4'-(4H-1,3,4-TRIAZOL-4-YLMETHYLENE)BIS 4,4'-((4H-1,2,4-Triazol-4-yl)methylene)dibenzonitrile 4,4'-((4H-1,2,4-Triazol-4-yl) Letrozole USP Impurity A Letrozole USP Related Compound A Benzonitrile, 4,4'-(4H-1,2,4-triazol-4-ylmethylene)bis- Letrozole EP Impurity A/ Letrozole Related Compound A (Iso Letrozole) 4-[α-(4-cyano-phenyl)-1-(1,3,4-triazol-1-yl)-methyl]-benzonitrile Letrozole EP Impurity A 4-[(4-cyanophenyl)-(1,2,4-triazol-4-yl)methyl]benzonitrile dibenzonitrile Letrozole EP Impurity A (Letrozole USP Related Compound A) Letrozole specified impurity A 4,4'-(1H-1,3,4-triazol-1-ylmethylene)dibenzonitrile/4,4'-(4H-1,2,4-Triazol-4-ylmethylene)bisbenzonitrile LETRAZOLE REALTED COMPOUND A 112809-52-6