Dicyclopropyl ketone
![Dicyclopropyl ketone Structure](CAS/20180808/GIF/1121-37-5.gif)
- CAS No.
- 1121-37-5
- Chemical Name:
- Dicyclopropyl ketone
- Synonyms
- DICYCLOPROPYLMETHANONE;CYCLOPROPYL KETONE;DICYCLOPROPYL KETONE;DicyclopropylKetone>DICYCLOPROPYLMETHYLOXIME;Dicyclopropyl ketone,95%;Methanone,dicyclopropyl-;Dicyclopropylmethanone 96%;Dicyclopropyl Ketone, 97+%;Dicyclopropyl-methanoneNSC
- CBNumber:
- CB8331519
- Molecular Formula:
- C7H10O
- Molecular Weight:
- 110.15
- MOL File:
- 1121-37-5.mol
- Modify Date:
- 2024/7/26 17:49:17
Melting point | 44.0-44.5 °C |
---|---|
Boiling point | 160-162 °C(lit.) |
Density | 0.977 g/mL at 25 °C(lit.) |
refractive index |
n |
Flash point | 103 °F |
storage temp. | Store below +30°C. |
Specific Gravity | 0.957 |
Water Solubility | Soluble in water. |
BRN | 774172 |
CAS DataBase Reference | 1121-37-5(CAS DataBase Reference) |
NIST Chemistry Reference | Methanone, dicyclopropyl-(1121-37-5) |
SAFETY
Risk and Safety Statements
Symbol(GHS) | ![]() GHS02 |
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Signal word | Warning | |||||||||
Hazard statements | H226 | |||||||||
Precautionary statements | P210-P233-P240-P241-P242-P243 | |||||||||
Hazard Codes | F,Xn | |||||||||
Risk Statements | 10-36/37/38-20/21/22-5 | |||||||||
Safety Statements | 16-36-26-3 | |||||||||
RIDADR | UN 1224 3/PG 3 | |||||||||
WGK Germany | 3 | |||||||||
Hazard Note | Harmful/Flammable | |||||||||
HazardClass | 3 | |||||||||
PackingGroup | III | |||||||||
HS Code | 29142900 | |||||||||
NFPA 704 |
|
Dicyclopropyl ketone price More Price(2)
Dicyclopropyl ketone Chemical Properties,Uses,Production
Chemical Properties
clear colourless to yellowish liquid
Uses
Dicyclopropyl Ketone is used as a reagent in the synthesis of a new class of potent and selective agonists of dimeric carbamoylguanidine-type histamine H2 receptor ligands. Also used in the preparation of chemical space analogs of PNU-282,987 and SSR180711, which have nicotinic receptor activity.
Preparation
Preparation of Dicyclopropyl ketone
Reaction: To a one liter three-necked flask fitted with a reflux condenser and a metal Hershberg stirrer there was added 600 ml. of 20% sodium hydroxide and 165g . (0.9mole) of 1,7 -dichloro-4-heptanone. The mixture was refluxed for 30 minutes with vigorous stirring, then steam distilled until the characteristic odor of dicyclopropyl ketone was absent from the distillate. The distillate was then saturated with potassium carbonate, the upper layer separated and the water layer extracted once with ether. The combined organic layers were dried over potassium carbonate. after removal of the ether there was dist illed 69g. (70%) of dicyclopropyl ketone, b.p . 69° at 20 mm, nD25 1.4648-1.4654.
Dicyclopropyl ketone Preparation Products And Raw materials
Raw materials
Preparation Products
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