PEPLOMYCIN SULFATE
- CAS No.
- 70384-29-1
- Chemical Name:
- PEPLOMYCIN SULFATE
- Synonyms
- Pepleo;NK 631;Nsc276382;PEPLOMYCIN SULFATE;Pepleomycin Sulfate;N1-[3-[[(1S)-1-phenylethyl]aMino]propyl]bleoMycinaMide;N1-[3-[[(1S)-1-phenylethyl]amino]propyl]bleomycinamide Sulfate;Bleomycinamide, N1-[3-[(1-phenylethyl)amino]propyl]-, (S)-, sulfate (1:1) (salt)
- CBNumber:
- CB8413187
- Molecular Formula:
- C61H90N18O25S3
- Molecular Weight:
- 1571.67
- MOL File:
- 70384-29-1.mol
- Modify Date:
- 2024/3/16 16:35:19
SAFETY
Risk and Safety Statements
| Toxicity | LD50 in male rats, mice (mg/kg): 234, 88 s.c.; 208, 85 i.p.; 245, 51 i.v. (Ito) |
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PEPLOMYCIN SULFATE Chemical Properties,Uses,Production
Description
Peplomycin was derived biosynthetically from Streptomyces verticillus, the bleomycinproducing organism, in the course of efforts to obtain bleomycin derivatives with high activity and low toxicity. This antibiotic was found by Nippon Kayaku Co. and the Institute of Microbial Chemistry, Japan, in 1974. Its anticancer effects appear earlier than those of bleomycin; consequently, the period of therapy is shortened. Peplomycin is also active against metastatic cancer of the lymph nodes and shows less pneumotoxicity than bleomycin.
Chemical Properties
Pale Yellow Amorphous Powder
Safety Profile
Poison by intraperitoneal, subcutaneous, and intravenous routes. Questionable carcinogen with experimental carcinogenic data. An eye irritant. When heated to decomposition it emits very toxic fumes of NOx and SOx.
PEPLOMYCIN SULFATE Preparation Products And Raw materials
PEPLOMYCIN SULFATE Suppliers
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6351 | 58 | Inquiry |
| BORI International Enterprises (Nanjing) Co., Ltd | 025-66916260 52209840 | China | 724 | 50 | Inquiry |
| BOC Sciences | 1-631-485-4226; 16314854226 | United States | 14059 | 65 | Inquiry |
| Wako Pure Chemical Industries, Ltd. | +81 6 6203 3741 | Japan | 6828 | 80 | Inquiry |
| Service Chemical Inc. | 888-895-6920 | Germany | 6373 | 71 | Inquiry |
| City Chemical LLC | 1-203-932-2489 | United States | 6710 | 72 | Inquiry |
| Yick-Vic Chemicals & Pharmaceuticals (HK) Ltd | (852)2541 2772 | China | 6214 | 58 | Inquiry |
| A.T.CHEMICAL | 0755-86655561 81899190 | China | 6594 | 51 | Inquiry |
| Waterstone Technology, LLC | 317 644 0862 | United States | 6801 | 30 | Inquiry |
| Medical Isotopes | 1-(603) 635-1722 | United States | 6185 | 68 | Inquiry |