CLOCORTOLONE PIVALATE

CLOCORTOLONE PIVALATE Structure
CAS No.
34097-16-0
Chemical Name:
CLOCORTOLONE PIVALATE
Synonyms
CL 68;SH-863;Cloderm;Purantix;clocortolone pivalate;Clocortolone 21-pivalate;Arbidol Impurity 6 Monomer;Clocortolone triMethylacetate;CLOCORTOLONE PIVALATE (200 MG);9-chloro-6α-fluoro-11β,21-dihydroxy-16α-methylpregna-1,4-diene-3
CBNumber:
CB8501376
Molecular Formula:
C27H36ClFO5
Molecular Weight:
495.02
MOL File:
34097-16-0.mol
MSDS File:
SDS
Modify Date:
2023/5/4 15:14:24

CLOCORTOLONE PIVALATE Properties

Melting point 231-233°C
Boiling point 598.0±50.0 °C(Predicted)
Density 1.24±0.1 g/cm3(Predicted)
storage temp. Refrigerator, under inert atmosphere
solubility Chloroform (Slightly), DMSO (Slightly), Ethanol (Slightly), Methanol (Slightly)
pka 13.04±0.70(Predicted)
form Solid
color White

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS08
Signal word  Danger
Hazard statements  H360-H372
Precautionary statements  P260-P264-P270-P314-P501
HS Code  2937220000

CLOCORTOLONE PIVALATE Chemical Properties,Uses,Production

Uses

Clocortolone Pivalate is a corticosteroid used in the treatment of atopic dermatitis.

Definition

ChEBI: The 21-O-pivalate ester of clocortolone. It is used for the relief of inflammatory and pruritic (itching) skin disorders.

General Description

Clocortolone pivalate, 9-chloro-21-(2,2-dimethyl-1-oxopropoxy)-6α-fluoro-11β-hydroxy-16α-methylpregna-1,4-diene-3,20-dione (Cloderm),along with desoximetasone, lacks the C17α oxygen functionalitythat is present in other GCs but still retains goodGC activity.

CLOCORTOLONE PIVALATE Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 46)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
Symbiotec Pharma Lab Pvt Ltd +91-7316676406 +91-7316676405 Madhya Pradesh, India 71 58 Inquiry
CLEARSYNTH LABS LTD. +91-22-45045900 Hyderabad, India 6351 58 Inquiry
SYMBIOTEC PHARMALAB PRIVATE LIMITED +91-731-4201222 New Delhi, India 22 58 Inquiry
Henan Tianfu Chemical Co.,Ltd. +86-0371-55170693 +86-19937530512 China 21662 55 Inquiry
BOC Sciences +1-631-485-4226 United States 19553 58 Inquiry
AFINE CHEMICALS LIMITED +86-0571-85134551 China 15372 58 Inquiry
Wuhan Topule Biopharmaceutical Co., Ltd +8618327326525 China 8474 58 Inquiry
Aladdin Scientific +1-+1(833)-552-7181 United States 57511 58 Inquiry
Shanghai Aladdin Biochemical Technology Co.,Ltd. +86-18521732826 China 48465 58 Inquiry
Nantong Hanfang Biotechnology Co. , Ltd. 18616537568 China 30968 58 Inquiry
9-chloro-6α-fluoro-11β,21-dihydroxy-16α-methylpregna-1,4-diene-3 CLOCORTOLONE PIVALATE (200 MG) 9-chloro-6alpha-fluoro-11beta,21-dihydroxy-16alpha-methylpregna-1,4-diene-3,20-dione 21-pivalate clocortolone pivalate 9-Chloro-6α,11β-dihydroxy-21-pivaloyloxy-16α-methylpregna-1,4-diene-3,20-dione SH-863 (6α,11β,16α)-9-Chloro-21-(2,2-diMethyl-1-oxopropoxy)-6-fluoro-11-hydroxy-16-Methypregna-1,4-diene-3,20-dione 9-Chloro-6α-fluoro-11β,21-dihydroxy-16α-Methylpregna-1,4-diene-3,20-dione 21-Pivalate CL 68 Clocortolone triMethylacetate Cloderm Purantix Pregna-1,4-diene-3,20-dione, 9-chloro-21-(2,2-dimethyl-1-oxopropoxy)-6-fluoro-11-hydroxy-16-methyl-, (6α,11β,16α)- Arbidol Impurity 6 Monomer Clocortolone 21-pivalate 34097-16-0 C27H36ClFO5 Intermediates & Fine Chemicals Pharmaceuticals Steroids