L-838417

L-838417 Structure

CAS No.: 286456-42-6

Chemical Name:: L-838417

Synonyms: L-838417;L-838417_x000b_;5-({[7-tert-butyl-3-(2,5-difluorophenyl)-[1,2,4]triazolo[4,3-b]pyridazin-6-yl]oxy}methyl)-1-methyl-1,2,4-triazole;7-(tert-Butyl)-3-(2,5-difluorophenyl)-6-((1-methyl-1H-1,2,4-triazol-5-yl)methoxy)-[1,2,4]triazolo[4,3-b]pyridazine;3-(2,5-Difluorophenyl)-7-(1,1-dimethylethyl)-6-[(1-methyl-1H-1,2,4,-triazol-5-yl)methoxy]-1,2,4-triazolo[4,3-b]pyridazine;1,2,4-Triazolo[4,3-b]pyridazine,3-(2,5-difluorophenyl)-7-(1,1-dimethylethyl)-6-[(1-methyl-1H-1,2,4-triazol-5-yl)methoxy]-;3-(2,5-Difluorophenyl)-7-(1,1-dimethylethyl)-6-[(1-methyl-1H-1,2,4,-triazol-5-yl)methoxy]-1,2,4-triazolo[4,3-β]pyridazine

CBNumber:: CB8506755

Molecular Formula:: C19H19F2N7O

Molecular Weight:: 399.4

MOL File:: 286456-42-6.mol

MSDS File:: SDS

Modify Date:: 2023/6/30 15:45:59

Request For Quotation

L-838417 Properties

Melting point	196-198°C
Density	1.40±0.1 g/cm3(Predicted)
storage temp.	Store at +4°C
solubility	DMSO: ≥20mg/mL
pka	2.13±0.10(Predicted)
form	powder
color	white to off-white

SAFETY

Risk and Safety Statements

WGK Germany	3

L-838417 Chemical Properties,Uses,Production

Chemical Properties

White to Off-White Solid

Uses

A selective ligand for GABAA receptors

Biological Activity

Subtype-selective GABA A receptor partial agonist. Selectively binds to α 1, α 2, α 3 and α 5 subunits (K i values are 0.79, 0.67, 0.67 and 2.25 nM respectively) but displays no efficacy at α 1 ( α 1-sparing). Exhibits non-sedative anxiolytic, antinociceptive and anti-inflammatory activity in vivo .

L-838417 Preparation Products And Raw materials

Raw materials

Preparation Products

L-838417 Suppliers

Global( 48)Suppliers

Supplier	Tel	Country	ProdList	Advantage	Inquiry
CLEARSYNTH LABS LTD.	+91-22-45045900	Hyderabad, India	6351	58	Inquiry
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	United States	19892	58	Inquiry
Zhejiang J&C Biological Technology Co.,Limited	+1-2135480471 +1-2135480471	China	10522	58	Inquiry
Shanghai Acmec Biochemical Technology Co., Ltd.	+undefined18621343501	China	33350	58	Inquiry
Suzhou ARTK Medchem Co., Ltd.	+8618168183658	China	39009	58	Inquiry
Amadis Chemical Company Limited	571-89925085	China	131980	58	Inquiry
Shanghai Hao Zhun Biological Technology Co., Ltd.	15800340161	CHINA	6846	58	Inquiry
Shanghai Yuda Industrial Co., Ltd.	021-64133189 13788995069	CHINA	6107	58	Inquiry
Shanghai Jingke Chemical Technology Co., Ltd.	021-54997581 13524423207	CHINA	6974	58	Inquiry
Shanghai Yubo Biotechnology Co., Ltd.	021-51875103 15026509758	CHINA	6322	58	Inquiry

Supplier	Advantage
CLEARSYNTH LABS LTD.	58
TargetMol Chemicals Inc.	58
Zhejiang J&C Biological Technology Co.,Limited	58
Shanghai Acmec Biochemical Technology Co., Ltd.	58
Suzhou ARTK Medchem Co., Ltd.	58
Amadis Chemical Company Limited	58
Shanghai Hao Zhun Biological Technology Co., Ltd.	58
Shanghai Yuda Industrial Co., Ltd.	58
Shanghai Jingke Chemical Technology Co., Ltd.	58
Shanghai Yubo Biotechnology Co., Ltd.	58

286456-42-6(L-838417)Related Search:

Phenylphosphonic dichloride N,N'-Diphenylurea 2-FLUOROPHENYL CYCLOPENTYL KETONE TRIS(PENTAFLUOROPHENYL)PHOSPHINE TRIS(PENTAFLUOROPHENYL)BORANE

(2-METHYL-2H-[1,2,4]TRIAZOL-3-YL)-METHANOL L-838417

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3-(2,5-Difluorophenyl)-7-(1,1-dimethylethyl)-6-[(1-methyl-1H-1,2,4,-triazol-5-yl)methoxy]-1,2,4-triazolo[4,3-β]pyridazine 7-(tert-Butyl)-3-(2,5-difluorophenyl)-6-((1-methyl-1H-1,2,4-triazol-5-yl)methoxy)-[1,2,4]triazolo[4,3-b]pyridazine 1,2,4-Triazolo[4,3-b]pyridazine,3-(2,5-difluorophenyl)-7-(1,1-dimethylethyl)-6-[(1-methyl-1H-1,2,4-triazol-5-yl)methoxy]- L-838417 3-(2,5-Difluorophenyl)-7-(1,1-dimethylethyl)-6-[(1-methyl-1H-1,2,4,-triazol-5-yl)methoxy]-1,2,4-triazolo[4,3-b]pyridazine 5-({[7-tert-butyl-3-(2,5-difluorophenyl)-[1,2,4]triazolo[4,3-b]pyridazin-6-yl]oxy}methyl)-1-methyl-1,2,4-triazole L-838417_x000b_ 286456-42-6 C19H19F2N7O Heterocycles Intermediates & Fine Chemicals Heterocyclic Compounds Pharmaceuticals