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4-Chloro-2,3-dimethylpyridine 1-oxide

CAS No.: 59886-90-7

Chemical Name:: 4-Chloro-2,3-dimethylpyridine 1-oxide

Synonyms: NSC 27526;nsc 275262;Lansoprazole-15;4-Chloro-2,3-dimethy;Rabeprazole Impurity 40;Lansoprazole Impurity 57;Lansoprazole Impurity B-9;Lansoprazole EP Impurity 16;3-DiMethyl-4-chloropyridine N-oxide;2,3-DiMethyl-4-chloropyridne-n-oxide

CBNumber:: CB8670430

Molecular Formula:: C7H8ClNO

Molecular Weight:: 157.6

MOL File:: 59886-90-7.mol

MSDS File:: SDS

Modify Date:: 2023/10/31 16:18:28

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4-Chloro-2,3-dimethylpyridine 1-oxide Properties

Melting point	103-105°C
Boiling point	338.5°C
Density	1.19
vapor pressure	0.346Pa at 25℃
Flash point	158.5°C
storage temp.	Room temperature.
solubility	Chloroform (Slightly), Methanol (Slightly)
form	Solid
pka	1.28±0.10(Predicted)
color	Pale Yellow to Light Beige
LogP	0.4 at 25℃
CAS DataBase Reference	59886-90-7(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07,GHS08

Signal word

Warning

Hazard statements

H315-H319-H341

Precautionary statements

P501-P202-P201-P264-P280-P302+P352-P308+P313-P337+P313-P305+P351+P338-P362+P364-P332+P313-P405

Safety Statements

24/25

HS Code

29333990

NFPA 704

	0
1		0

4-Chloro-2,3-dimethylpyridine 1-oxide price More Price(2)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
TCI Chemicals (India)	C2820	4-Chloro-2,3-dimethylpyridine N-Oxide min. 98.0 %	59886-90-7	5G	₹6100	2022-05-26	Buy
TCI Chemicals (India)	C2820	4-Chloro-2,3-dimethylpyridine N-Oxide min. 98.0 %	59886-90-7	25G	₹12700	2022-05-26	Buy

Product number	Packaging	Price	Buy
C2820	5G	₹6100	Buy
C2820	25G	₹12700	Buy

4-Chloro-2,3-dimethylpyridine 1-oxide Chemical Properties,Uses,Production

Chemical Properties

Pale Yellow Solid

Uses

An intermediate in the synthesis of rabeprazole (R070500).

Synthesis

83.0 g (0.49 mol) of 4-nitro-2,3-dimethylpyridine N-oxide and 90 g (1.54 mol) of NaCl were admixed with 1350 ml of CH3CN, 180 ml of aq. HCl (36%) and 16.6 g of benzyltributylammonium chloride, and the resulting suspension was boiled under reflux with stirring for 12 h. The resulting reaction mixture was adjusted to PH=9 using 350 ml of 20% NaOH, wherefor the existing precipitate largely dissolved. The organic phase was separated off, water was added to the aqueous phase until the precipitate had completely dissolved, and it was subsequently extracted using dichloromethane. The organic phases were combined and the solvent was removed under reduced pressure. 76.6 g (98.5%) of 4-Chloro-2,3-dimethylpyridine 1-oxide were obtained.

4-Chloro-2,3-dimethylpyridine 1-oxide Preparation Products And Raw materials

Raw materials

Hydrogen peroxide Ethyl acetate Hydrochloric acid Nitric acid Dichloromethane

Acetic acid 2,3-Lutidine Sulfuric acid 4-Nitro-2,3-lutidine-N-oxide 2,3-Dimethylpyridine-N-oxide

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Preparation Products

4-Chloro-2,3-dimethylpyridine 1-oxide Suppliers

Global( 289)Suppliers

Supplier	Tel	Country	ProdList	Advantage	Inquiry
Enal Drugs Pvt Ltd	+914044753636	Telangana, India	35	58	Inquiry
Integrin Life Sciences. Pvt. Ltd.	+91-4040265469 +91-9849990870	Hyderabad, India	90	58	Inquiry
Raising Sun Pharma	+91-9399941155 +91-9399941155	Telangana, India	127	58	Inquiry
Integrin Life Sciences. Pvt. Ltd.	91-40-40265469	Hyderabad, India	29	58	Inquiry
ENAL DRUGS PRIVATE LIMITED	+91-40- 44753636	New Delhi, India	27	58	Inquiry
Shivam Pharma Chemicals	91-22-26403900	Maharashtra, India	656	58	Inquiry
Cameo Health Care (India) Private Limited	+91 22 25326282	Maharashtra, India	47	58	Inquiry
LEE PHARMA LIMITED	+91-40-23770338	New Delhi, India	35	58	Inquiry
Rushi Healthcare Pvt., Ltd.	91-22-26200440	Maharashtra, India	50	58	Inquiry
OCEAN TRADING CORPORATION	+91(22) 24921669	New Delhi, India	6211	58	Inquiry

Supplier	Advantage
Enal Drugs Pvt Ltd	58
Integrin Life Sciences. Pvt. Ltd.	58
Raising Sun Pharma	58
Integrin Life Sciences. Pvt. Ltd.	58
ENAL DRUGS PRIVATE LIMITED	58
Shivam Pharma Chemicals	58
Cameo Health Care (India) Private Limited	58
LEE PHARMA LIMITED	58
Rushi Healthcare Pvt., Ltd.	58
OCEAN TRADING CORPORATION	58

59886-90-7(4-Chloro-2,3-dimethylpyridine 1-oxide)Related Search:

ETHYLENE OXIDE Aluminum oxide Zinc oxide 4-Chloropyridinium chloride 2,6-Lutidine

Chlorodimethylphenylsilane tert-Butyldimethylsilyl chloride Clopidol Iron oxide DIMETHYLTHEXYLSILYL CHLORIDE

NITRIC OXIDE Pyridine-N-oxide CHLORODIMETHYLVINYLSILANE 2,3-Lutidine Sodium oxide

(Diethoxymethyl)diphenylphosphine oxide 4-Chloropyridine N-oxide 2,3-Dimethylpyridine-N-oxide

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4-Chloro-2,3-dimethylpyridine-N-oxide ,98% 4-Chloro-2,3-dimethy 3-DiMethyl-4-chloropyridine N-oxide 4-chloro-2,3-diMethyl-1$l^{5}-pyridin-1-one 2,3-DiMethyl-4-chloropyridne-n-oxide 4-Chloro-2,3-lutidine N-oxide, 4-Chloro-2,3-dimethylpyridinium-1-olate nsc 275262 2,3-DIMETHYL-4-CHLOROPYRIDINE-N-OXIDE 4-Chloro-2,3-Dimethyl Pyridine-N-Oxide 99% Pyridine-N-oxide, 4-chloro-2,3-dimethyl 4-CHLORO-2,3-DIMETHYL-PYRIDINE 1-OXIDE 4-CHLORO-2,3-DIMETHYLPYRIDINE-N-OXIDE 2,3-Dimethyl-4-Chloro Pyridine-1-Oxide NSC 27526 Pyridine, 4-chloro-2,3-dimethyl-, 1-oxide Lansoprazole Impurity B-9 Lansoprazole-15 Lansoprazole Impurity 57 4-Chloro-2,3-dimethylpyridine N-Oxide > 4-Chloro-2,3-dimethylpyridine 1-oxide ISO 9001：2015 REACH 59886-90-7 4-Chloro-2,3-dimethylpyridine 1-oxide Rabeprazole Impurity 40 Lansoprazole EP Impurity 16 59886-90-7 Nitric Oxide Reagents Heterocycle-Pyridine series Rabeprazole PHARMACEUTICAL INTERMEDIATES Pyridines Intermediates of Rabeprazole Heterocycles bc0001