FURIN INHIBITOR II
- CAS No.
- 673202-67-0
- Chemical Name:
- FURIN INHIBITOR II
- Synonyms
- H-(D)RRRRRR-NH2;HEXA-D-ARGININE;FURIN INHIBITOR II;Hexa-D-arginine aMide;Hexa-D-arginine,RRRRRR;Furin Inhibitor II, >98%;Furin Inhibitor II(Hexa-D-arginine);H-D-ARG-D-ARG-D-ARG-D-ARG-D-ARG-D-ARG-NH2;D-Argininamide,D-arginyl-D-arginyl-D-arginyl-D-arginyl-D-arginyl-;D-Argininamide, D-arginyl-D-arginyl-D-arginyl-D-arginyl-D-arginyl- (9CI)
- CBNumber:
- CB8719126
- Molecular Formula:
- C36H75N25O6
- Molecular Weight:
- 954.14
- MOL File:
- 673202-67-0.mol
- MSDS File:
- SDS
- Modify Date:
- 2024/7/2 8:55:37
| Density | 1.59±0.1 g/cm3(Predicted) |
|---|---|
| storage temp. | Keep in dark place,Sealed in dry,Store in freezer, under -20°C |
| solubility | H2O : 50 mg/mL (52.40 mM; Need ultrasonic)DMSO : 5 mg/mL (5.24 mM; Need ultrasonic) |
| pka | 13.24±0.46(Predicted) |
| form | lyophilized |
| color | White to off-white |
| Water Solubility | Soluble to 2 mg/ml in water |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H315-H319 |
| Precautionary statements | P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313 |
| WGK Germany | 3 |
FURIN INHIBITOR II Chemical Properties,Uses,Production
Uses
Furin Inhibitor II has been used as a furin inhibitor:
- to study its effects on transforming growth factor β1 (TGF-β1) induced glial cell line-derived neurotrophic factor (GDNF) production in non-tumorigenic immortalized human granulosa cell line (SVOG).
- to study its effect on cleavage of (Pro) renin receptor (PRR) induced by bovine serum albumin (BSA) in human kidney 2 (HK-2) cells.
- in furin cleavage assay.
General Description
Furin is a calcium-dependent serine endoproteinase and belongs to the subtilisin-like proprotein/prohormone convertase (PC) family. It is distributed ubiquitously and has a rhythmic movement between the trans-Golgi network, cell surface and the endosomes.
Biochem/physiol Actions
Furin plays a role in processing several pro-proteins such as, bone morphogenetic protein?4 (BMP-4), insulin receptor and Notch1 receptor. It also processes human immune deficiency virus 1 (HIV-1) glycoprotein gp160, several metalloproteases?and pro-β-nerve growth (pro-β-NGF) factor. Furin is also involved in cleaving transforming growth factor β1 (TGF-β1).
FURIN INHIBITOR II Preparation Products And Raw materials
Raw materials
Preparation Products
FURIN INHIBITOR II Suppliers
Global( 71)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| Shenzhen Nexconn Pharmatechs Ltd | +86-755-89396905 +86-15013857715 | China | 10312 | 58 | Inquiry |
| BOC Sciences | +1-631-485-4226 | United States | 19553 | 58 | Inquiry |
| career henan chemical co | +86-0371-86658258 +8613203830695 | China | 29826 | 58 | Inquiry |
| Zhejiang J&C Biological Technology Co.,Limited | +1-2135480471 +1-2135480471 | China | 10522 | 58 | Inquiry |
| Nextpeptide Inc | +86-0571-81612335 +8613336028439 | China | 19915 | 58 | Inquiry |
| Alfa Chemistry | United States | 24072 | 58 | Inquiry | |
| Chengdu Youngshe Chemical Co., Ltd. | +8618108235634 | China | 2345 | 58 | Inquiry |
| LEAP CHEM CO., LTD. | +86-852-30606658 | China | 24738 | 58 | Inquiry |
| TargetMol Chemicals Inc. | +1-781-999-5354 | United States | 19973 | 58 | Inquiry |
| Hebei Miaoyin Technology Co.,Ltd | +86-17367732028 +86-17367732028 | China | 3582 | 58 | Inquiry |
673202-67-0(FURIN INHIBITOR II)Related Search:
HEXA-D-ARGININE
H-(D)RRRRRR-NH2
FURIN INHIBITOR II
H-D-ARG-D-ARG-D-ARG-D-ARG-D-ARG-D-ARG-NH2
Hexa-D-arginine aMide
D-ArgininamideD-arginyl-D-arginyl-D-arginyl-D-arginyl-D-arginyl-D-alanine
Furin Inhibitor II, >98%
Hexa-D-arginine,RRRRRR
D-Argininamide, D-arginyl-D-arginyl-D-arginyl-D-arginyl-D-arginyl- (9CI)
D-Argininamide,D-arginyl-D-arginyl-D-arginyl-D-arginyl-D-arginyl-
inhibit,furin,Furin Inhibitor II,TNF-α,PACE4,noncytotoxic,PC1,anthrax,PEA,HexaDarginine,Hexa D arginine,exotoxins,Inhibitor
Furin Inhibitor II(Hexa-D-arginine)
673202-67-0
C36H75N25O6