MOTILIN (HUMAN, PORCINE)
- CAS No.
- 52906-92-0
- Chemical Name:
- MOTILIN (HUMAN, PORCINE)
- Synonyms
- motilin;MOTILIN, PORCINE;Motilin (9CI, ACI);MOTILIN PORCINE ≥97%;FVPIFTYGELQRMQEKERNKGQ;Motilin, porcine, ≥97% (HPLC);Gastricmotorstimulatorypeptide;Motilin (26-47), human, porcine;GASTRIC MOTOR STIMULATORY PEPTIDE, PORCINE;PHE-VAL-PRO-ILE-PHE-THR-TYR-GLY-GLU-LEU-GLN-ARG-MET-GLN-GLU-LYS-GLU-ARG-ASN-LYS-GLY-GLN
- CBNumber:
- CB8732572
- Molecular Formula:
- C120H188N34O35S
- Molecular Weight:
- 2699.05
- MOL File:
- 52906-92-0.mol
- MSDS File:
- SDS
- Modify Date:
- 2024/7/2 8:55:37
MOTILIN (HUMAN, PORCINE) price More Price(2)
MOTILIN (HUMAN, PORCINE) Chemical Properties,Uses,Production
General Description
Motilin is a 22-residue polypeptide isolated from the duodenum.Its secretion is stimulated by the presence of acid inthe duodenum. Motilin inhibits gastric motor activity anddelays gastric emptying.
Structure and conformation
Motilin is highly conserved across species, and is synthesized as a part of a larger inactive prohormone. Structure-activity studies with analogs and fragments of porcine motilin have shown an N-terminal region, which is considered a
physiological and biological active site, and a C-terminal
α-helical domain. Human motilin is synthesized as a preprohormone composed of 133 aa residues, each consisting
of a 25-aa signal peptide followed by a 22-aa (mature motilin) and a C-terminal motilin-associated peptide (MAP). In the N-terminal region, identical aa sequences exist
in human and porcine motilin, but differ from canine
motilin at positions 7, 8, 12, 13, and 14 . Chicken MLN also differs from human and porcine
sequences by six residues at positions 4, 7–10, and
12, and the binding affinity and pharmacological
potency against the chicken MLNR differ from those
for mammalian MLN.
MOTILIN (HUMAN, PORCINE) Preparation Products And Raw materials
Raw materials
Preparation Products
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