N-NITROSODIETHYLAMINE
- CAS No.
- 55-18-5
- Chemical Name:
- N-NITROSODIETHYLAMINE
- Synonyms
- NDEA;DEN;DANA;Nitrosodiethylamine;DENA;Ethanamine, N-ethyl-N-nitroso-;N,N-diethylnitrous amide;DIETHYLNITROSAMINE;N-Nitrosodiethylamine (1mg/mL in Methanol);NSC 132
- CBNumber:
- CB8732709
- Molecular Formula:
- C4H10N2O
- Molecular Weight:
- 102.14
- MOL File:
- 55-18-5.mol
- MSDS File:
- SDS
- Modify Date:
- 2023/6/8 17:06:39
| Melting point | <25℃ |
|---|---|
| Boiling point | 177 °C (lit.) |
| Density | 0.95 g/mL (lit.) |
| vapor pressure | 1.7 mmHg at 20 °C |
| refractive index |
n |
| storage temp. | 2-8°C |
| solubility | Chloroform (Soluble), Ethyl Acetate (Slightly), Methanol (Slightly) |
| form | liquid |
| pka | -3.14±0.70(Predicted) |
| color | yellow |
| Water Solubility | 106.2g/L(24 ºC) |
| Merck | 6636 |
| BRN | 1744991 |
| Stability | Stable, but light sensitive. Combustible. Incompatible with strong oxidizing agents, reducing agents. |
| CAS DataBase Reference | 55-18-5(CAS DataBase Reference) |
| IARC | 2A (Vol. 17, Sup 7) 1987 |
| EPA Substance Registry System | N-Nitrosodiethylamine (55-18-5) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS06,GHS08 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H301-H350-H412 | |||||||||
| Precautionary statements | P202-P264-P270-P273-P280-P301+P310 | |||||||||
| Hazard Codes | T,F | |||||||||
| Risk Statements | 45-22-39/23/24/25-23/24/25-11 | |||||||||
| Safety Statements | 53-45-36/37-16 | |||||||||
| RIDADR | UN 2810 6.1/PG 3 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | IA3500000 | |||||||||
| HazardClass | 6.1(b) | |||||||||
| PackingGroup | III | |||||||||
| HS Code | 29299090 | |||||||||
| Toxicity | LD50 oral (rat) 280 mg/kg | |||||||||
| NFPA 704 |
|
N-NITROSODIETHYLAMINE price More Price(8)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | N0756 | N-Nitrosodiethylamine liquid | 55-18-5 | 10ML | ₹17146.8 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | N0756 | N-Nitrosodiethylamine liquid | 55-18-5 | 25ML | ₹34542.58 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | N0258 | N-Nitrosodiethylamine ISOPAC? | 55-18-5 | 1G | ₹9655.9 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | 73861 | N-Nitrosodiethylamine ≥99.0% (GC) | 55-18-5 | 10ML | ₹17255.05 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | 442687 | N-Nitrosodiethylamine analytical standard | 55-18-5 | 1000MG | ₹12708.55 | 2022-06-14 | Buy |
N-NITROSODIETHYLAMINE Chemical Properties,Uses,Production
Chemical Properties
N-Nitrosodiethylamine is a yellow liquid.
Uses
N-Nitrosodiethylamine (DEN) is a widely occurring nitrosamine that is one of the most important environmental carcinogens primarily inducing tumors of liver.
Definition
ChEBI: A nitrosamine that is N-ethylethanamine substituted by a nitroso group at the N-atom.
General Description
Clear slightly yellow liquid. Boiling point 175-177°C. Can reasonably be anticipated to be a carcinogen. Used as a gasoline and lubricant additive and as an antioxidant and stabilizer in plastics.
Air & Water Reactions
Water soluble.
Reactivity Profile
N-NITROSODIETHYLAMINE reacts with strong oxidizing agents. Incompatible with reducing agents. Can be hydrolyzed by hydrogen bromide in acetic acid .
Hazard
Possible carcinogen; mutagen; neoplastigen; tumorigen; poison; teratogen.
Health Hazard
ACUTE/CHRONIC HAZARDS: When heated to decomposition N-NITROSODIETHYLAMINE emits toxic fumes of nitrogen oxides.
Fire Hazard
N-NITROSODIETHYLAMINE is combustible.
Flammability and Explosibility
Volatilization during combustion produces hazardous vapors. Combustion products contain nitrogen oxides.
Safety Profile
Confirmed carcinogen with experimental carcinogenic, neoplastigenic, and tumorigenic data. Poison by ingestion, intravenous, intraperitoneal, and subcutaneous routes. An experimental teratogen. Other experimental reproductive effects. Human mutation data reported. A transplacental carcinogen. When heated to decomposition it emits toxic fumes of NOx. See also N-NITROSO COMPOUNDS and AMINES.
Potential Exposure
An additive in gasoline and lubricants; an antioxidant and stabilizer in plastics. Used in research. Incompatibilities: Incompatible with oxidizers (chlorates, nitrates, peroxides, permanganates, perchlorates, chlorine, bromine, fluorine, etc.); contact may cause fires or explosions. Keep away from alkaline materials, strong bases, strong acids, oxoacids, epoxides. Contact with reducing agents may form hydrazine; hydrogen bromide. Light sensitive; rapidly decomposes.
Carcinogenicity
N-Nitrosodiethylamine is reasonably anticipated to be a human carcinogen based on sufficient evidence of carcinogenicity from studies in experimental animals.
storage
work with diethylnitrosamine should be conducted in a fume hood to prevent exposure by inhalation, and appropriate impermeable gloves and splash goggles should be worn at all times to prevent skin and eye contact.
Shipping
UN2810 Toxic liquids, organic, n.o.s., Hazard Class: 6.1; Labels: 6.1-Poisonous materials, Technical Name Required. UN3082 Environmentally hazardous substances, liquid, n.o.s., Hazard Class: 9; Labels: 9-Miscellaneous hazardous material, Technical Name Required.
Incompatibilities
An additive in gasoline and lubricants; an antioxidant and stabilizer in plastics. Used in research. Incompatibilities: Incompatible with oxidizers (chlorates, nitrates, peroxides, permanganates, perchlorates, chlorine, bromine, fluorine, etc.); contact may cause fires or explosions. Keep away from alkaline materials, strong bases, strong acids, oxoacids, epoxides. Contact with reducing agents may form hydrazine; hydrogen bromide. Light sensitive; rapidly decomposes.
Waste Disposal
Consult with environmental regulatory agencies for guidance on acceptable disposal practices. Generators of waste containing this contaminant (≥100 kg/mo) must conform with EPA regulations governing storage, transportation, treatment, and waste disposal. Under 40 CFR 261.5 small quantity generators of this waste may qualify for partial exclusion from hazardous waste regulations.
N-NITROSODIETHYLAMINE Preparation Products And Raw materials
Raw materials
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chevron_rightPreparation Products
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| SYNRYN PHARMA PVT LTD | +91 9392615244 | Telangana, India | 115 | 58 | Inquiry |
| Ganapa Liife Science | +91 7760536535 | Bangalore, India | 168 | 58 | Inquiry |
| DR MARK LABORATORIES PVT LTD | +91-9963004025 +91-9963004025 | Telangana, India | 47 | 58 | Inquiry |
| WARUKSHA LABORATORIES PVT LTD | +91-7485988764 +91-7485988764 | Gujarat, India | 77 | 58 | Inquiry |
| GLP Pharma Standards | +91 9866074638 | Hyderabad, India | 1644 | 58 | Inquiry |
| KARPSCHEM LABORATORIES | +91-7249203006 +91-7249203006 | Maharashtra, India | 786 | 58 | Inquiry |
| Svak Life Sciences | +91-9963463333 +91-9705383777 | Hyderabad, India | 101 | 58 | Inquiry |
| VIVAN Life Sciences Pvt Ltd | +91-2225870080 +91-9987465183 | Maharashtra, India | 49 | 58 | Inquiry |
| Orgamine Chemicals(I) Pvt Ltd | +91-9820080281 +91-9820080281 | Maharashtra, India | 451 | 58 | Inquiry |
| Synchemia Research Chemical | +91-9766925136 +91-7276018915 | Maharashtra, India | 27 | 58 | Inquiry |
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