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Indapamide

Indapamide Structure
CAS No.
26807-65-8
Chemical Name:
Indapamide
Synonyms
INDAPAMID;indaflex;Idapamide;ndapamide;N-(4-CHLORO-3-SULFAMOYLBENZAMIDO)-2-METHYLINDOLINE;4-chloro-N-[(2S)-2-Methyl-2,3-dihydro-1H-indol-1-yl]-3-sulfaMoylbenzaMide;s1520;lozol;tandix;damide
CBNumber:
CB2420420
Molecular Formula:
C16H16ClN3O3S
Molecular Weight:
365.83
MOL File:
26807-65-8.mol
MSDS File:
SDS
Modify Date:
2024/7/3 16:00:59
Request For Quotation

Indapamide Properties

Melting point 160-162°C
Boiling point 110.4°C (rough estimate)
alpha -0.8～+0.8°(D/20℃) (c=5, C2H5OH)
Density 1.2895 (rough estimate)
refractive index 1.6100 (estimate)
storage temp. -20°C Freezer
solubility Practically insoluble in water, soluble in ethanol (96 per cent).
pka pKa (25°) 8.8 ± 0.2
form Solid
color White to Off-White
Water Solubility Soluble in ethanol. Insoluble in water
Merck 14,4935
BCS Class 1
InChIKey NDDAHWYSQHTHNT-UHFFFAOYSA-N
CAS DataBase Reference 26807-65-8(CAS DataBase Reference)
EPA Substance Registry System Benzamide, 3-(aminosulfonyl)-4-chloro-N-(2,3-dihydro-2-methyl-1H-indol-1-yl)- (26807-65-8)

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS08
Signal word  Warning
Hazard statements  H361d-H362
Precautionary statements  P202-P260-P263-P264-P270-P308+P313
WGK Germany  2
RTECS  CV2451200
HS Code  2935904000
Toxicity LD50 in rats, mice, guinea pigs (mg/kg): 393-421, 410-564, 347-416 i.p.; 394-440, 577-635, 272-358 i.v.; >3000 all species orally (Kyncl)

Indapamide price More Price(3)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) I1887 Indapamide analytical standard, for drug analysis 26807-65-8 250MG ₹5639.83 2022-06-14 Buy
Sigma-Aldrich(India) PHR1660 Indapamide Pharmaceutical Secondary Standard; Certified Reference Material 26807-65-8 1G ₹9645.08 2022-06-14 Buy
Sigma-Aldrich(India) I1887 Indapamide analytical standard, for drug analysis 26807-65-8 5G ₹25893.4 2022-06-14 Buy
Product number Packaging Price Buy
I1887 250MG ₹5639.83 Buy
PHR1660 1G ₹9645.08 Buy
I1887 5G ₹25893.4 Buy

Indapamide Chemical Properties,Uses,Production

Description

Indapamide is a derivative of benzolsulfonamide and its mechanism of action is analogous to that of thiazides. It is intended for lowering arterial blood pressure and as an adjuvant drug for treating edema caused by cardiac insufficiency.

Chemical Properties

Crystalline Solid

Definition

ChEBI: A sulfonamide formed by condensation of the carboxylic group of 4-chloro-3-sulfamoylbenzoic acid with the amino group of 2-methyl-2,3-dihydro-1H-indol-1-amine.

Clinical Use

Indapamide is an effective diuretic drug when GFR falls below 40 mL/min. The duration of action is approximately 24 hours, with the normal oral adult dosage starting at 2.5 mg given each morning. The dose may be increased to 5.0 mg/day, but doses beyond this level do not appear to provide additional results.

Side effects

Effects on urine content and side effects are similar to effects induced by thiazide diuretics.

Indapamide Preparation Products And Raw materials

Raw materials

1-Amino-2-methylindoline hydrochloride 4-Chloro-5-sulphamoylbenzoic acid INDAPAMIDE RELATED COMPOUND A (50 MG) (4-CHLORO-N-(2-METHYL-INDOL-1-YL)-3-SULFAMOYLBEN-ZAMIDE) (AS) 2-Methylindolin-1-amine 4-Chloro-3-sulfamoylbenzoyl chloride
2-Methylindoline
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Preparation Products

Indapamide Suppliers

Global( 443)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
Darsh PharmaChem Pvt Ltd +91-9712983850 +91-9712983850 Gujarat, India 33 58 Inquiry
Ipca Laboratories Ltd +91-2262105000 +91-2262105000 Maharashtra, India 61 58 Inquiry
Moleculochem 9811853366 New Delhi, India 25 58 Inquiry
Solara Active Pharma Sciences Ltd +91-8046632100 +91-7075706520 Bangalore, India 65 58 Inquiry
Tivan Sciences Pvt Ltd +91-9081499099 +91-9081499099 Gujarat, India 14 58 Inquiry
Ralington Pharma +91-7948911722 +91-9687771722 Gujarat, India 1350 58 Inquiry
Humble Healthcare Limited +91-9720093000 +91-8006400378 Uttar Pradesh, India 141 58 Inquiry
Biophore India Pharmaceuticals Pvt Ltd +91-9100031592 +91-9030907714 Telangana, India 134 58 Inquiry
BDR Pharmaceuticals International Pvt Ltd +91-2240560560 +91-7718884418 Maharashtra, India 206 58 Inquiry
Sanvin Group of Companies (Pioneer Agro Industries) +91-2261066638 +91-2261066600 Maharashtra, India 27 58 Inquiry
Supplier Advantage
Darsh PharmaChem Pvt Ltd 58
Ipca Laboratories Ltd 58
Moleculochem 58
Solara Active Pharma Sciences Ltd 58
Tivan Sciences Pvt Ltd 58
Ralington Pharma 58
Humble Healthcare Limited 58
Biophore India Pharmaceuticals Pvt Ltd 58
BDR Pharmaceuticals International Pvt Ltd 58
Sanvin Group of Companies (Pioneer Agro Industries) 58

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Indapamide Spectrum

Indapamide(26807-65-8)1HNMR

26807-65-8(Indapamide)Related Search:

2-Methylindole Benzamide Epichlorohydrin Chlorantraniliprole Sulclamide
2-Methylindoline (-Indapamide-d3,rac Indapamide-d3 INDAPAMIDE RELATED COMPOUND A (50 MG) (4-CHLORO-N-(2-METHYL-INDOL-1-YL)-3-SULFAMOYLBEN-ZAMIDE) (AS) IndapaMide iMpurity 5 4-Chloro-3-sulfamoylbenzoyl chloride
(±)-2-methyl-1-nitrosoindoline 5-hydroxyindapamide Indapamide Impurity 11 4-Chloro-5-sulphamoylbenzoic acid 2-(trideuteriomethyl)-2,3-dihydro-1H-indole
Indapamide Impurity 14 4-CHLORO-3-CHLOROSULFONYLBENZOIC ACID Indapamide Impurity F
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N-[4-CHLORO-3-SULFAMOYL-BENZAMIDOL]-2-METHYLINDOLINE INDAPAMIDE 3-(aminosulfonyl)-4-chloro-n-(2,3-dihydro-2-methyl-1h-indol-1-yl)-benzamid 3-(aminosulfonyl)-4-chloro-n-(2,3-dihydro-2-methyl-1h-indol-1-yl)benzamide 4-chloro-n-(2-methyl-1-indolinyl)-3-sulfamoyl-benzamid natrilix noranat s1520 se-1520 tandix IndapaMide(Lozol) IndapaMide API indaparnide 1-(4-chloro-3-sulfamoylbenzamido)-2-methylindoline 4-chloro-n-(2-methyl-1-indolinyl)-3-sulfamoylbenzamide bajaten damide fludex indamol ipamix lozol IndapamideC16H16C1N303S 4-Chloro-N-(2-methyl-1-indolymyl)-3-sulfamolybenzamide Arifon Flubest Idamide rac Indapamide Veroxil Benzamide, 3-(aminosulfonyl)-4-chloro-N-(2,3-dihydro-2-methyl-1H-indol-1-yl)- INDAPAMIDE USP Benzamide, 4-chloro-N-(2-methyl-1-indolinyl)-3-sulfamoyl- (8CI) Fludin Flupamid Indamide Racemic indapamide Tertensif Indapamidum Benzamide, 4-chloro-N-(2-methyl-1-indolinyl)-3-sulfamoyl- Lonzol Cormil Indapamide (250 mg) 1-(4-CHLORO-3-SULFAMOYLBENAZMIDO)-2-METHYL INDOLINE Levetiracetam Solution, 100ppm 3-(aminosulfonyl)-4-chloro-N-(2-methyl-2,3-dihydro-1H-indol-1-yl)benzamide Indapamide RS Indapamide, racemic mixture Indapamide CRS Indapamide USP/EP/BP 4-chloro-N-(2-methyl-2,3-dihydro-1H-indol-1-yl)-3- sulfamoylbenzamide Indapamide(I0150000)Q: What is Indapamide(I0150000) Q: What is the CAS Number of Indapamide(I0150000) IndapamideQ: What is Indapamide Q: What is the CAS Number of Indapamide Q: What is the storage condition of Indapamide Q: What are the applications of Indapamide Indapamide 13C D3Q: What is Indapamide 13C D3 Q: What is the CAS Number of Indapamide 13C D3 Q: What is the storage condition of Indapamide 13C D3 Q: What are the applications of Indapamide 13C D3 (R)-1-"3 , 5-bis(trifluoromethyl)phenyl”ethanol ,TFM indaflex Idapamide INDAPAMID ndapamide 4-chloro-N-[(2S)-2-Methyl-2,3-dihydro-1H-indol-1-yl]-3-sulfaMoylbenzaMide