Indapamide
Indapamide
- CAS:
- 26807-65-8
- MF:
- C16H16ClN3O3S
- MW:
- 365.83
Suppliers by country/region
Company Type
Properties
- Melting point:
- 160-162°C
- Boiling point:
- 110.4°C (rough estimate)
- alpha
- -0.8～+0.8°(D/20℃) (c=5, C2H5OH)
- Density
- 1.2895 (rough estimate)
- refractive index
- 1.6100 (estimate)
- storage temp.
- -20°C Freezer
- solubility
- Practically insoluble in water, soluble in ethanol (96 per cent).
- pka
- pKa (25°) 8.8 ± 0.2
- form
- Solid
- color
- White to Off-White
- Water Solubility
- Soluble in ethanol. Insoluble in water
- Merck
- 14,4935
- BCS Class
- 1
- InChIKey
- NDDAHWYSQHTHNT-UHFFFAOYSA-N
Safety Information
- Symbol(GHS)
GHS08
- Signal word
- Warning
- Hazard statements
- H361d-H362
- Precautionary statements
- P202-P260-P263-P264-P270-P308+P313
- WGK Germany
- 2
- RTECS
- CV2451200
- HS Code
- 2935904000
- Toxicity
- LD50 in rats, mice, guinea pigs (mg/kg): 393-421, 410-564, 347-416 i.p.; 394-440, 577-635, 272-358 i.v.; >3000 all species orally (Kyncl)
Use
Indapamide is currently the most popular non-prescription diuretic antihypertensive drug with good efficacy, stable blood pressure, fewer side effects, etc. it was originally developed for the first time by the french servier (servier) pharmaceutical company. indapamide have diuretic and calcium antagonist dual effect by inhibiting the proximal end of the distal convoluted tubule na+ reabsorption, resulting in diuresis, while by blocking ca2+ influx especially a higher selectivity for vascular smooth muscle to dilate the small blood vessels of the outer periphery, resulting in antihypertensive effect. but the effect to vascular smooth muscle is stronger than the diuretic effect.
48 India supplier list of "Indapamide"
- Product Name:Indapamide
- Products Intro:Purity: 99% | Package: 1 kg,5 kg, 10 kg,25kg
- Company Type: Manufacturer
- Country/Region: Gujarat,INDIA
- Product Name:Indapamide
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Reagent
- Country/Region: New Delhi,INDIA
- Product Name:Indapamide
- Products Intro:Purity: 99% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Reagent
- Country/Region: Maharashtra,INDIA
- Product Name:Indapamide
- Products Intro:Purity: 99% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Manufacturer
- Country/Region: Uttar Pradesh,INDIA
- Product Name:Indapamide
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Reagent
- Country/Region: Bangalore,INDIA
- Product Name:Indapamide
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Reagent
- Country/Region: Gujarat,INDIA
- Product Name:Indapamide
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Reagent
- Country/Region: Maharashtra,INDIA
- Product Name:Indapamide
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Reagent
- Country/Region: Telangana,INDIA
- Product Name:Indapamide
- Products Intro:Purity: 99% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Reagent
- Country/Region: Gujarat,INDIA
- Product Name:Indapamide
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Manufacturer
- Country/Region: Maharashtra,INDIA