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FENTIAZAC

FENTIAZAC Structure
CAS No.
18046-21-4
Chemical Name:
FENTIAZAC
Synonyms
ch800;br700;flogene;donorest;norvedan;FENTIAZAC;Donorest|||Flogene|||BR-700;4-(4-chlorophenyl)-2-phenyl-5-thiazoleaceticaci;4-(p-chlorophenyl)-2-phenyl-5-thiazoleaceticaci;4-(p-chlorophenyl)-2-phenylthiazole-5-aceticacid
CBNumber:
CB8736909
Molecular Formula:
C17H12ClNO2S
Molecular Weight:
329.8
MOL File:
18046-21-4.mol
Modify Date:
2024/7/2 8:55:37
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FENTIAZAC Properties

Melting point 162°C
Boiling point 556.2±60.0 °C(Predicted)
Density 1.1592 (rough estimate)
refractive index 1.6100 (estimate)
pka 3.89±0.10(Predicted)
form Solid
color White to off-white
Water Solubility 31.66mg/L(25 ºC)

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P305+P351+P338
Risk Statements  36/37/38
Safety Statements  26-36/37/39
Toxicity LD50 in rats, mice (mg/kg): 661, 692 orally (Marmo)

FENTIAZAC Chemical Properties,Uses,Production

Uses

Anti-inflammatory.

General Description

Fentiazac is reported to have anti-inflammatory, analgesic, and antipyretic activity. It has been given once or twice a day at levels between 100 and 200 mg/dose in the treatment of postoperative pain, including that following orthopedic surgery. The most common adverse effect is gastrointestinal intolerance, including epigastric pain, nausea, and vomiting. Effects on the CNS, such as headache and dizziness, also have been reported.

Trade name

Atilan (Zambon, Brazil), Donorest (Fontoura-Wyeth, Brazil), Flogene (Polifarma, Italy), Norvedan (Boehringer Mannheim, Austria; LPB, Italy).

Synthesis

Synthesis: refluxing a mixture of 3-bromo- 3-(4-chlorobenzoyl)propionic acid and thiobenzamide in ethanol gives ethyl 2-phenyl-4-(4- chlorophenyl)thiazole-5-acetate, which is then saponified to yield fentiazac.
synthesis of FENTIAZAC

FENTIAZAC Preparation Products And Raw materials

Raw materials

4,4'-Carbonyldiphthalic acid 4'-CHLOROBUTYROPHENONE THIOBENZAMIDE Potassium thioacetate Benzonitrile

Preparation Products

FENTIAZAC Suppliers

Global( 17)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
TargetMol Chemicals Inc. +1-781-999-5354 +1-00000000000 United States 19892 58 Inquiry
Finetech Industry Limited +86-27-87465837 +8618971612321 China 9618 58 Inquiry
Shaanxi Didu New Materials Co. Ltd +86-89586680 +86-13289823923 China 9003 58 Inquiry
Finetech Industry Limited 027-87465837 19945049750 China 9612 58 Inquiry
Shaanxi Xihua Chemical Industry Co., Ltd 17691182729 15529505138 China 9963 58 Inquiry
TargetMol Chemicals Inc. 15002134094 China 28091 58 Inquiry
Shanghai Haohong Pharmaceutical Co., Ltd. 4008210725 4008210725 China 54986 58 Inquiry
VWR International 800 932 5000 United Kingdom 6554 82 Inquiry
3B Scientific Corporation 847.281.9822 United States 6744 47 Inquiry
UK GREEN SCIENTIFIC CO.,LIMITED +44(0)870 432 4488 United Kingdom 6107 47 Inquiry
Supplier Advantage
TargetMol Chemicals Inc. 58
Finetech Industry Limited 58
Shaanxi Didu New Materials Co. Ltd 58
Finetech Industry Limited 58
Shaanxi Xihua Chemical Industry Co., Ltd 58
TargetMol Chemicals Inc. 58
Shanghai Haohong Pharmaceutical Co., Ltd. 58
VWR International 82
3B Scientific Corporation 47
UK GREEN SCIENTIFIC CO.,LIMITED 47

FENTIAZAC Spectrum

FENTIAZAC(18046-21-4)MSFENTIAZAC(18046-21-4)1HNMRFENTIAZAC(18046-21-4)13CNMRFENTIAZAC(18046-21-4)IR1

18046-21-4(FENTIAZAC)Related Search:

2-PHENYLTHIAZOLE 4-METHYL-5-THIAZOLEACETIC ACID 2-(2,4-DIPHENYL-1,3-THIAZOL-5-YL)ACETIC ACID (2,4-DIMETHYL-THIAZOL-5-YL)-ACETIC ACID FENTIAZAC
METHYL 2-[4-(4-CHLOROPHENYL)-2-PHENYL-1,3-THIAZOL-5-YL]ACETATE 4-(4-CHLOROPHENYL)-2-METHYL-1,3-THIAZOL-5-YL]ACETIC ACID 1,3-THIAZOL-5-YLACETIC ACID (2-METHYL-1,3-THIAZOL-5-YL)ACETIC ACID
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FENTIAZAC 4-(4-chlorophenyl)-2-phenyl-5-thiazoleaceticacid 4-(p-chlorophenyl)-2-phenyl-5-thiazoleaceticaci 4-(p-chlorophenyl)-2-phenyl-5-thiazoleaceticacid 4-(p-chlorophenyl)-2-phenylthiazole-5-aceticacid 4-(4-Chlorlphenyl)-2-phenyl-5-thiazoleacetic acid br700 ch800 donorest 4-(4-chlorophenyl)-2-phenyl-5-thiazoleaceticaci flogene norvedan [4-(4-Chloro-phenyl)-2-phenyl-thiazol-5-yl]-acetic acid 5-Thiazoleacetic acid, 4-(4-chlorophenyl)-2-phenyl- Donorest|||Flogene|||BR-700 18046-21-4 8046-21-4