METHYL 7-METHOXY-1H-INDAZOLE-3-CARBOXYLATE

METHYL 7-METHOXY-1H-INDAZOLE-3-CARBOXYLATE Structure
CAS No.
885278-95-5
Chemical Name:
METHYL 7-METHOXY-1H-INDAZOLE-3-CARBOXYLATE
Synonyms
Methyl 7-Methoxy-2H-indazole-3-carboxylate;METHYL 7-METHOXY-1H-INDAZOLE-3-CARBOXYLATE;1H-Indazole-3-carboxylic acid, 7-methoxy-, methyl ester
CBNumber:
CB8752947
Molecular Formula:
C10H10N2O3
Molecular Weight:
206.2
MOL File:
885278-95-5.mol
Modify Date:
2023/7/23 8:30:07

METHYL 7-METHOXY-1H-INDAZOLE-3-CARBOXYLATE Properties

Melting point 141-142 °C
Boiling point 382.2±22.0 °C(Predicted)
Density 1.313±0.06 g/cm3(Predicted)
pka 11.26±0.40(Predicted)

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P305+P351+P338

METHYL 7-METHOXY-1H-INDAZOLE-3-CARBOXYLATE Chemical Properties,Uses,Production

Uses

Methyl 7-Methoxy-2H-indazole-3-carboxylate is an intermediate in the synthesis of 7-Hydroxy Granisetron (H942675), a metabolite of Granisetron (G780000), a specific serotonin (5HT3) receptor antagonist. Used as an antiemetic. Granisetron HCl is a serotonin 5-HT3 receptor antagonist used as an antiemetic to treat nausea and vomiting following chemotherapy. Its main effect is to reduce the activity of the vagus nerve. It does not have much effect on vomiting due to motion sickness. This drug does not have any effect on dopamine receptors or muscarinic receptor.

METHYL 7-METHOXY-1H-INDAZOLE-3-CARBOXYLATE Preparation Products And Raw materials

Raw materials

Preparation Products

METHYL 7-METHOXY-1H-INDAZOLE-3-CARBOXYLATE Suppliers

Global( 20)Suppliers
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CLEARSYNTH LABS LTD. +91-22-45045900 Hyderabad, India 6351 58 Inquiry
A.J Chemicals 91-9810153283 New Delhi, India 6124 58 Inquiry
Amadis Chemical Company Limited 571-89925085 China 131980 58 Inquiry
Combi-Blocks Inc. 858 635 8950 United States 6632 69 Inquiry
United States Biological 800.520.3011 or 781.639.5092 United States 6256 80 Inquiry
J & W PharmLab, LLC 1 215 428 9468 United States 4157 63 Inquiry
Chem-Impex International, Inc. 800 869-9290 US and Canada only United States 6740 64 Inquiry
J & K SCIENTIFIC LTD. 010-82848833 400-666-7788 China 94658 76 Inquiry
ShangHai AmK Pharmaceutical Technology Co., Ltd. 18019252918 China 15364 55 Inquiry
Shenzhen Polymeri Biochemical Technology Co., Ltd. +86-400-002-6226 13028896684 China 56070 58 Inquiry
METHYL 7-METHOXY-1H-INDAZOLE-3-CARBOXYLATE Methyl 7-Methoxy-2H-indazole-3-carboxylate 1H-Indazole-3-carboxylic acid, 7-methoxy-, methyl ester 885278-95-5