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Ceramide

Ceramide Structure
CAS No.
104404-17-3
Chemical Name:
Ceramide
Synonyms
CERAMIDE;CERAMIDE;CERAMIDE;CERAMIDE;CERAMIDE;N-oleoylsphingosine;Ceramide (d18:1/16:0);Ceramide (d18:1/12:0);Ceramide (d18:1/18:0);Ceramide (d18:1/20:0)
CBNumber:
CB8764212
Molecular Formula:
C34H66NO3R
Molecular Weight:
536.89
MOL File:
104404-17-3.mol
MSDS File:
SDS
Modify Date:
2024/5/8 14:48:35

Ceramide Properties

InChIKey XJRPTDNTEPSGLZ-UHFFFAOYSA-N
SMILES C(OC(C)=O)(C(CCCCCCCCCCCCCC)OC(C)=O)C(CO)NC(CCCCCCCCCCCCCCCCCCCCCCCCC)=O

Ceramide Chemical Properties,Uses,Production

benefits

Ceramides are lipids, which are fatty acids that are produced in the sebaceous glands. Ceramides help to moisturise and strengthen the protective skin moisture barrier, and protect the skin from external aggressors such as weather and pollution.

Mode of action

Topically applied ceramide (Cer) could improve barrier function in three possible ways: (1) Cer in an appropriate formulation constructs (lamellar) liquid crystalline and/or gel structures; (2) Cer is likely incorporated into lamellar bilayer structures in the SC to repair incompetent bilayer structures; and/or (3) Cer penetrates into nucleated layers of the epidermis and becomes a precursor to endogenous Cer synthesis following hydrolysis to the sphingoid base and FA. In addition, Cer absorbed into nucleated layers of the epidermis could suppress KC proliferation and promote differentiation. Because Cer production is increased during KC differentiation, the stimulation of KC differentiation can increase de novo Cer production, thereby contributing to barrier formation[1].

References

[1] Kyong-Oh Shin. “Exogenous Ceramide Serves as a Precursor to Endogenous Ceramide Synthesis and as a Modulator of Keratinocyte Differentiation.” Cells (2022).

Ceramide Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 67)Suppliers
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Chongqing Zhihe Biopharmaceutical Co., Ltd. +86-18580541567 +86-17782035140 China 301 58 Inquiry
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career henan chemical co +86-0371-86658258 +8613203830695 China 29897 58 Inquiry
Hebei Guanlang Biotechnology Co., Ltd. +86-19930503282 China 8826 58 Inquiry
CERAMIDE Ceramide?(saturated,?unsaturated?and?a-OH?fatty?acids) Ceramide (d18:1/12:0) N-((2S,3R,E)-1,3-dihydroxyoctadec-4-en-2-yl)dodecanamide Ceramide (d18:1/16:0) (2S,3R,4E)-2-acylamino-1,3-octadec-4-enediol 1-O-[O-(N-Acetyl-ALPHA-neuraminosyl)-(2.fwdarw.3)-O-[O-B-D-galactopyranosyl N-octadecanoylsphingosine N-icosanoylsphingosine N-docosanoylsphingosine N-hexacosanoylsphingosine N-oleoylsphingosine Ceramide/rice bran extract N-((2S,3R,E)-1,3-dihydroxyoctadec-4-en-2-yl)hexadecanamide Ceramide (d18:1/18:0) N-((2S,3R,E)-1,3-dihydroxyoctadec-4-en-2-yl)octadecanamide Ceramide (d18:1/20:0) N-((2S,3R,E)-1,3-dihydroxyoctadec-4-en-2-yl)icosanamide Ceramide (d18:1/22:0) N-((2S,3R,E)-1,3-dihydroxyoctadec-4-en-2-yl)docosanamide Ceramide (d18:1/24:0) N-((2S,3R,E)-1,3-dihydroxyoctadec-4-en-2-yl)tetracosanamide (Z)-N-((2S,3R,E)-1,3-dihydroxyoctadec-4-en-2-yl)tetracos-15-enamide Ceramide (d18:1/24:1(15Z)) Ceramide (d18:1/25:0) N-((2S,3R,E)-1,3-dihydroxyoctadec-4-en-2-yl)pentacosanamide Ceramide (d18:1/26:0) N-((2S,3R,E)-1,3-dihydroxyoctadec-4-en-2-yl)hexacosanamide (Z)-N-((2S,3R,E)-1,3-dihydroxyoctadec-4-en-2-yl)hexacos-17-enamide Ceramide (d18:1/26:1(17Z)) (Z)-N-((2S,3R,E)-1,3-dihydroxyoctadec-4-en-2-yl)octadec-9-enamide Ceramide (d18:1/9Z-18:1) CERAMIDE ISO 9001:2015 REACH CERAMIDE CERAMIDE CERAMIDE CERAMIDE 104404-17-3 C30H59NO3 C40H79NO3 C42H83NO3 C43H85NO3 C44H87NO3 C44H85NO3 C48H93NO6