2,4-Dichloro-5-methylpyridine
- CAS No.
- 56961-78-5
- Chemical Name:
- 2,4-Dichloro-5-methylpyridine
- Synonyms
- 4,6-Dichloro-3-picoline;2,4-Dichloro-5-Picoline;2,4-DICHLORO-5-METHYLPYRIDINE;Pyridine, 2,4-dichloro-5-methyl-;2,4-Dichloro-5-methylpyridine 98%;2,4-Dichloro-5-methylpyridine ISO 9001：2015 REACH;2,4-dichloro-5-methylpyridine 2,4-dichloro-5-picoline;2,4-Dichloro-5-methylpyridine Synonyms: 2,4-DICHLORO-5-METHYLPYRIDINE
- CBNumber:
- CB8801111
- Molecular Formula:
- C6H5Cl2N
- Molecular Weight:
- 162.02
- MOL File:
- 56961-78-5.mol
- MSDS File:
- SDS
- Modify Date:
- 2024/4/8 16:27:35
| Boiling point | 221.2±35.0 °C(Predicted) |
|---|---|
| Density | 1.319±0.06 g/cm3(Predicted) |
| storage temp. | Inert atmosphere,Room Temperature |
| pka | 0.38±0.10(Predicted) |
| form | Liquid |
| color | Colorless |
| Water Solubility | Slightly soluble in water. |
| InChI | InChI=1S/C6H5Cl2N/c1-4-3-9-6(8)2-5(4)7/h2-3H,1H3 |
| InChIKey | DUPJNQNLAKJWKU-UHFFFAOYSA-N |
| SMILES | C1(Cl)=NC=C(C)C(Cl)=C1 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |    GHS05,GHS06,GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302-H301-H315-H318-H335 | |||||||||
| Precautionary statements | P261-P280a-P301+P310a-P305+P351+P338-P405-P501a | |||||||||
| Hazard Codes | Xn | |||||||||
| Risk Statements | 22 | |||||||||
| HS Code | 2933399990 | |||||||||
| NFPA 704 |
|
2,4-Dichloro-5-methylpyridine Chemical Properties,Uses,Production
Chemical Properties
colorless liquid
Uses
2,4-Dichloro-5-methylpyridine is used as pharmaceutical intermediates.
Synthesis
A solution of phosphorus oxychloride in dichloromethane was added to a mixture of 2-chloro-5-methylpyridine 1-oxide and triethylamine in dichloromethane at 0 ℃. After stirring for 2 hours, the mixture is reacted at room temperature for 24 hours. After that, the water was added and the mixture was neutralized with a sodium hydroxide solution. The organic layer was washed with a saturated brine solution and the aqueous layer was extracted with ethyl acetate and washed with a saturated brine solution. The combined organic layers were dried over magnesium sulfate, filtered, and concentrated under reduced pressure to afford 2,4-Dichloro-5-methylpyridine. The by-product of this reaction is 2,6-dichloro-3-methyl-pyridine.
2,4-Dichloro-5-methylpyridine Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| CHATURYA BIOTECH | +91-7702707258 +91-7702707258 | Telangana, India | 479 | 58 | Inquiry |
| Sintilla Medcoms Pvt Ltd | +91-4027808001 +91-8886733867 | Telangana, India | 307 | 58 | Inquiry |
| Prodev Pharma Pvt Ltd | +91-9963029529 +91-9043422844 | Telangana, India | 102 | 58 | Inquiry |
| Vital synthetics | +917799889789 | Telangana, India | 98 | 58 | Inquiry |
| OCEAN TRADING CORPORATION | +91(22) 24921669 | New Delhi, India | 6211 | 58 | Inquiry |
| A.J Chemicals | 91-9810153283 | New Delhi, India | 6124 | 58 | Inquiry |
| Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 | China | 20293 | 58 | Inquiry |
| Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 | China | 29798 | 60 | Inquiry |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | China | 32836 | 60 | Inquiry |
| Jinan Carbotang Biotech Co.,Ltd. | +8615866703830 | China | 7621 | 58 | Inquiry |
| Supplier | Advantage |
|---|---|
| CHATURYA BIOTECH | 58 |
| Sintilla Medcoms Pvt Ltd | 58 |
| Prodev Pharma Pvt Ltd | 58 |
| Vital synthetics | 58 |
| OCEAN TRADING CORPORATION | 58 |
| A.J Chemicals | 58 |
| Henan Fengda Chemical Co., Ltd | 58 |
| Capot Chemical Co.,Ltd. | 60 |
| ATK CHEMICAL COMPANY LIMITED | 60 |
| Jinan Carbotang Biotech Co.,Ltd. | 58 |