3,4-BIS-DIFLUOROMETHOXY-BENZALDEHYDE

3,4-BIS-DIFLUOROMETHOXY-BENZALDEHYDE Structure
CAS No.
127842-54-0
Chemical Name:
3,4-BIS-DIFLUOROMETHOXY-BENZALDEHYDE
Synonyms
Roflumilast Impurity K;3,4-BIS-DIFLUOROMETHOXY-BENZALDEHYDE;Benzaldehyde, 3,4-bis(difluoroMethoxy)-
CBNumber:
CB8842044
Molecular Formula:
C9H6F4O3
Molecular Weight:
238.14
MOL File:
127842-54-0.mol
Modify Date:
2023/4/23 13:52:06

3,4-BIS-DIFLUOROMETHOXY-BENZALDEHYDE Properties

Boiling point 265.8±35.0℃ (760 Torr)
Density 1.387±0.06 g/cm3 (20 ºC 760 Torr)
Flash point 111.1±20.8℃
storage temp. under inert gas (nitrogen or Argon) at 2-8°C
solubility Chloroform (Slightly), Methanol (Slightly)
form Oil
color Clear Light Yellow

SAFETY

Risk and Safety Statements

HS Code  2912490090

3,4-BIS-DIFLUOROMETHOXY-BENZALDEHYDE Chemical Properties,Uses,Production

Chemical Properties

Yellow Oil

Uses

3,4-Bis(difluoromethoxy)benzaldehyde is an impurity of the antiasthmatic drug Roflumilast (R639700). 3,4-Bis(difluoromethoxy)benzaldehyde is used in the preparation of diphenylethylene compounds as PDE4 (phosphodiesterase-4) inhibitors for treatment of cancer, CNS disorders, and inflammatory disorders.

3,4-BIS-DIFLUOROMETHOXY-BENZALDEHYDE Preparation Products And Raw materials

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Benzaldehyde, 3,4-bis(difluoroMethoxy)- 3,4-BIS-DIFLUOROMETHOXY-BENZALDEHYDE Roflumilast Impurity K 127842-54-0 Aromatics Intermediates Intermediates & Fine Chemicals Pharmaceuticals