LY 344864

- CAS No.
- 186544-26-3
- Chemical Name:
- LY 344864
- Synonyms
- CS-660;Y344864;LY 344864;LY344864 HCL;LY344864;LY-344864;LY 344864 hydrochloride;LY 344864 hydrochloride, 5-HT1F agonist;(R)-N-[3-(Dimethylamino)-2,3,4,9-tetrahydro-1H-carbazol-6-yl]-4-fluorobenzamide;Benzamide, N-[(3R)-3-(dimethylamino)-2,3,4,9-tetrahydro-1H-carbazol-6-yl]-4-fluoro-;(R)-N-(3-(Dimethylamino)-2,3,4,9-tetrahydro-1H-carbazol-6-yl)-4-fluorobenzamide hydrochloride
- CBNumber:
- CB8847478
- Molecular Formula:
- C21H22FN3O
- Molecular Weight:
- 351.42
- MOL File:
- 186544-26-3.mol
- MSDS File:
- SDS
- Modify Date:
- 2025/4/17 18:22:24
LY 344864 Chemical Properties,Uses,Production
Biological Activity
Potent, selective 5-HT 1F receptor agonist (EC 50 = 3 nM). Displays > 80-fold selectivity over other 5-HT receptors (K i values are 0.006, 0.53, 0.55, 0.56, 1.42, 1.70, 3.50, 3.94 and 4.85 μ M for 5-HT 1F , 5-HT 1A , 5-HT 1B , 5-HT 1D , 5-HT 1E , 5-HT 2B , 5-HT 2C , 5-HT 2A and 5-HT 7 receptors respectively). Inhibits neurogenic dural inflammation in vivo following i.v. and oral administration.
LY 344864 Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 66)Suppliers
Supplier | Tel | Country | ProdList | Advantage | Inquiry |
---|---|---|---|---|---|
ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | China | 33024 | 60 | Inquiry |
career henan chemical co | +86-0371-86658258 +8613203830695 | China | 29808 | 58 | Inquiry |
SHANGHAI T&W PHARMACEUTICAL CO., LTD. | +86-021-61551413 +8618813727289 | China | 5738 | 58 | Inquiry |
TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | United States | 32248 | 58 | Inquiry |
InvivoChem | +1-708-310-1919 +1-13798911105 | United States | 6391 | 58 | Inquiry |
LEAP CHEM CO., LTD. | +86-852-30606658 | China | 24727 | 58 | Inquiry |
Aladdin Scientific | United States | 52924 | 58 | Inquiry | |
TargetMol Chemicals Inc. | +8613564774135 | United States | 19898 | 58 | Inquiry |
DAYANG CHEM (HANGZHOU) CO.,LTD | +8617705817739 | China | 53900 | 58 | Inquiry |
Amadis Chemical Company Limited | 571-89925085 | China | 131957 | 58 | Inquiry |
186544-26-3(LY 344864)Related Search:
LY 344864
LY 344864 hydrochloride
N-[(3R)-3-(Dimethylamino)-2,3,4,9-tetrahydro-1H-carbazol-6-yl]-4-fluorobenzamidehydrochloride
(R)-N-[3-(Dimethylamino)-2,3,4,9-tetrahydro-1H-carbazol-6-yl]-4-fluorobenzamide
(R)-N-(3-(Dimethylamino)-2,3,4,9-tetrahydro-1H-carbazol-6-yl)-4-fluorobenzamide hydrochloride
LY344864 HCL
LY344864;LY-344864
CS-660
Y344864
Benzamide, N-[(3R)-3-(dimethylamino)-2,3,4,9-tetrahydro-1H-carbazol-6-yl]-4-fluoro-
migraines,Adrenergic Receptor,BBB penetration,Serotonin Receptor,inhibit,5-HT Receptor,LY-344864,Beta Receptor,Parkinson’s disease,LY 344864,Inhibitor,5-hydroxytryptamine Receptor,5-HT1F
LY 344864 hydrochloride, 5-HT1F agonist
186544-26-3
C21H22N3OFHCl
Inhibitors