LY 344864

CAS No.: 186544-26-3

Chemical Name:: LY 344864

Synonyms: CS-660;Y344864;LY 344864;LY344864 HCL;LY344864;LY-344864;LY 344864 hydrochloride;LY 344864 hydrochloride, 5-HT1F agonist;(R)-N-[3-(Dimethylamino)-2,3,4,9-tetrahydro-1H-carbazol-6-yl]-4-fluorobenzamide;Benzamide, N-[(3R)-3-(dimethylamino)-2,3,4,9-tetrahydro-1H-carbazol-6-yl]-4-fluoro-;(R)-N-(3-(Dimethylamino)-2,3,4,9-tetrahydro-1H-carbazol-6-yl)-4-fluorobenzamide hydrochloride

CBNumber:: CB8847478

Molecular Formula:: C21H22FN3O

Molecular Weight:: 351.42

MOL File:: 186544-26-3.mol

MSDS File:: SDS

Modify Date:: 2025/4/17 18:22:24

Request For Quotation

LY 344864 Properties

Boiling point	471.9±45.0 °C(Predicted)
Density	1.28±0.1 g/cm3(Predicted)
storage temp.	Store at +4°C
solubility	DMSO : ≥ 350 mg/mL (995.96 mM)
pka	14.12±0.40(Predicted)
form	Powder
color	White to off-white
Water Solubility	water: 10mM DMSO: 100mM

LY 344864 Chemical Properties,Uses,Production

Biological Activity

Potent, selective 5-HT 1F receptor agonist (EC 50 = 3 nM). Displays > 80-fold selectivity over other 5-HT receptors (K i values are 0.006, 0.53, 0.55, 0.56, 1.42, 1.70, 3.50, 3.94 and 4.85 μ M for 5-HT 1F , 5-HT 1A , 5-HT 1B , 5-HT 1D , 5-HT 1E , 5-HT 2B , 5-HT 2C , 5-HT 2A and 5-HT 7 receptors respectively). Inhibits neurogenic dural inflammation in vivo following i.v. and oral administration.

LY 344864 Preparation Products And Raw materials

Raw materials

Preparation Products

LY 344864 Suppliers

Global( 66)Suppliers

Supplier	Tel	Country	ProdList	Advantage	Inquiry
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	China	33024	60	Inquiry
career henan chemical co	+86-0371-86658258 +8613203830695	China	29808	58	Inquiry
SHANGHAI T&W PHARMACEUTICAL CO., LTD.	+86-021-61551413 +8618813727289	China	5738	58	Inquiry
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	United States	32248	58	Inquiry
InvivoChem	+1-708-310-1919 +1-13798911105	United States	6391	58	Inquiry
LEAP CHEM CO., LTD.	+86-852-30606658	China	24727	58	Inquiry
Aladdin Scientific		United States	52924	58	Inquiry
TargetMol Chemicals Inc.	+8613564774135	United States	19898	58	Inquiry
DAYANG CHEM (HANGZHOU) CO.,LTD	+8617705817739	China	53900	58	Inquiry
Amadis Chemical Company Limited	571-89925085	China	131957	58	Inquiry

Supplier	Advantage
ATK CHEMICAL COMPANY LIMITED	60
career henan chemical co	58
SHANGHAI T&W PHARMACEUTICAL CO., LTD.	58
TargetMol Chemicals Inc.	58
InvivoChem	58
LEAP CHEM CO., LTD.	58
Aladdin Scientific	58
TargetMol Chemicals Inc.	58
DAYANG CHEM (HANGZHOU) CO.,LTD	58
Amadis Chemical Company Limited	58

186544-26-3(LY 344864)Related Search:

(R)-3-Amino-1,2,3,4-tetrahydrocarbazole Ciclindole 3-(2-DIMETHYLAMINO-ETHYL)-1H-INDOL-5-YLAMINE 3-Amino-1,2,3,4-tetrahydrocarbazol LY 344864

LY 344864 LY 344864 hydrochloride N-[(3R)-3-(Dimethylamino)-2,3,4,9-tetrahydro-1H-carbazol-6-yl]-4-fluorobenzamidehydrochloride (R)-N-[3-(Dimethylamino)-2,3,4,9-tetrahydro-1H-carbazol-6-yl]-4-fluorobenzamide (R)-N-(3-(Dimethylamino)-2,3,4,9-tetrahydro-1H-carbazol-6-yl)-4-fluorobenzamide hydrochloride LY344864 HCL LY344864;LY-344864 CS-660 Y344864 Benzamide, N-[(3R)-3-(dimethylamino)-2,3,4,9-tetrahydro-1H-carbazol-6-yl]-4-fluoro- migraines,Adrenergic Receptor,BBB penetration,Serotonin Receptor,inhibit,5-HT Receptor,LY-344864,Beta Receptor,Parkinson’s disease,LY 344864,Inhibitor,5-hydroxytryptamine Receptor,5-HT1F LY 344864 hydrochloride, 5-HT1F agonist 186544-26-3 C21H22N3OFHCl Inhibitors