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LY 344864

LY 344864 Structure
CAS No.
186544-26-3
Chemical Name:
LY 344864
Synonyms
CS-660;Y344864;LY 344864;LY344864 HCL;LY344864;LY-344864;LY 344864 hydrochloride;(R)-N-[3-(Dimethylamino)-2,3,4,9-tetrahydro-1H-carbazol-6-yl]-4-fluorobenzamide;Benzamide, N-[(3R)-3-(dimethylamino)-2,3,4,9-tetrahydro-1H-carbazol-6-yl]-4-fluoro-;(R)-N-(3-(Dimethylamino)-2,3,4,9-tetrahydro-1H-carbazol-6-yl)-4-fluorobenzamide hydrochloride;N-[(3R)-3-(Dimethylamino)-2,3,4,9-tetrahydro-1H-carbazol-6-yl]-4-fluorobenzamidehydrochloride
CBNumber:
CB8847478
Molecular Formula:
C21H22FN3O
Molecular Weight:
351.42
MOL File:
186544-26-3.mol
MSDS File:
SDS
Modify Date:
2024/7/2 8:55:39
Request For Quotation

LY 344864 Properties

Boiling point 471.9±45.0 °C(Predicted)
Density 1.28±0.1 g/cm3(Predicted)
storage temp. Store at +4°C
solubility DMSO : ≥ 350 mg/mL (995.96 mM)
pka 14.12±0.40(Predicted)
form Powder
color White to off-white

LY 344864 Chemical Properties,Uses,Production

Biological Activity

Potent, selective 5-HT 1F receptor agonist (EC 50 = 3 nM). Displays > 80-fold selectivity over other 5-HT receptors (K i values are 0.006, 0.53, 0.55, 0.56, 1.42, 1.70, 3.50, 3.94 and 4.85 μ M for 5-HT 1F , 5-HT 1A , 5-HT 1B , 5-HT 1D , 5-HT 1E , 5-HT 2B , 5-HT 2C , 5-HT 2A and 5-HT 7 receptors respectively). Inhibits neurogenic dural inflammation in vivo following i.v. and oral administration.

LY 344864 Preparation Products And Raw materials

Raw materials

Preparation Products

LY 344864 Suppliers

Global( 58)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
ATK CHEMICAL COMPANY LIMITED +undefined-21-51877795 China 32760 60 Inquiry
career henan chemical co +86-0371-86658258 +8613203830695 China 29826 58 Inquiry
SHANGHAI T&W PHARMACEUTICAL CO., LTD. +86-021-61551413 +8618813727289 China 5738 58 Inquiry
TargetMol Chemicals Inc. +1-781-999-5354 +1-00000000000 United States 19892 58 Inquiry
InvivoChem +1-708-310-1919 +1-13798911105 United States 6393 58 Inquiry
LEAP CHEM CO., LTD. +86-852-30606658 China 24738 58 Inquiry
Aladdin Scientific +1-+1(833)-552-7181 United States 52927 58 Inquiry
Amadis Chemical Company Limited 571-89925085 China 131980 58 Inquiry
Matrix Scientific 803 788-9494 All other calls United States 6655 80 Inquiry
Shenzhen Polymeri Biochemical Technology Co., Ltd. +86-400-002-6226 13028896684 China 56057 58 Inquiry
Supplier Advantage
ATK CHEMICAL COMPANY LIMITED 60
career henan chemical co 58
SHANGHAI T&W PHARMACEUTICAL CO., LTD. 58
TargetMol Chemicals Inc. 58
InvivoChem 58
LEAP CHEM CO., LTD. 58
Aladdin Scientific 58
Amadis Chemical Company Limited 58
Matrix Scientific 80
Shenzhen Polymeri Biochemical Technology Co., Ltd. 58

186544-26-3(LY 344864)Related Search:

(R)-3-Amino-1,2,3,4-tetrahydrocarbazole Ciclindole 3-(2-DIMETHYLAMINO-ETHYL)-1H-INDOL-5-YLAMINE 3-Amino-1,2,3,4-tetrahydrocarbazol LY 344864
LY 344864 LY 344864 hydrochloride N-[(3R)-3-(Dimethylamino)-2,3,4,9-tetrahydro-1H-carbazol-6-yl]-4-fluorobenzamidehydrochloride (R)-N-[3-(Dimethylamino)-2,3,4,9-tetrahydro-1H-carbazol-6-yl]-4-fluorobenzamide (R)-N-(3-(Dimethylamino)-2,3,4,9-tetrahydro-1H-carbazol-6-yl)-4-fluorobenzamide hydrochloride LY344864 HCL LY344864;LY-344864 CS-660 Y344864 Benzamide, N-[(3R)-3-(dimethylamino)-2,3,4,9-tetrahydro-1H-carbazol-6-yl]-4-fluoro- migraines,Adrenergic Receptor,BBB penetration,Serotonin Receptor,inhibit,5-HT Receptor,LY-344864,Beta Receptor,Parkinson’s disease,LY 344864,Inhibitor,5-hydroxytryptamine Receptor,5-HT1F 186544-26-3 C21H22N3OFHCl Inhibitors