4-Methylumbelliferyl-beta-D-glucopyranoside
![4-Methylumbelliferyl-beta-D-glucopyranoside Structure](CAS/GIF/18997-57-4.gif)
- CAS No.
- 18997-57-4
- Chemical Name:
- 4-Methylumbelliferyl-beta-D-glucopyranoside
- Synonyms
- MUD;MUG;MU-Glu;MUGGAL;MU-GAL;7-(B2;4-MU-GLU;GLC1-B-4MU;MUGLUCOSIDE;4-MU-β-Gluc
- CBNumber:
- CB8853266
- Molecular Formula:
- C16H18O8
- Molecular Weight:
- 338.31
- MOL File:
- 18997-57-4.mol
- Modify Date:
- 2023/9/4 15:51:00
Melting point | 258-263 °C (dec.) |
---|---|
Boiling point | 394.46°C (rough estimate) |
Density | 1.522 |
refractive index | 1.4430 (estimate) |
storage temp. | Sealed in dry,Store in freezer, under -20°C |
solubility | DMF: 5 mg/ml; DMSO: 50 mg/ml |
pka | 12.73±0.70(Predicted) |
form | Powder |
color | White to off-white |
Water Solubility | Soluble in DMF or water |
λmax | 320nm(Buffer)(lit.) |
BRN | 94672 |
CAS DataBase Reference | 18997-57-4(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
Symbol(GHS) | ![]() GHS07 |
---|---|
Signal word | Warning |
Hazard statements | H302-H315-H319-H335 |
Precautionary statements | P261-P280-P301+P312-P302+P352-P305+P351+P338 |
Hazard Codes | T+ |
Risk Statements | 26/27/28 |
Safety Statements | 22-24/25 |
WGK Germany | 3 |
F | 3-10-21 |
HS Code | 29389090 |
4-Methylumbelliferyl-beta-D-glucopyranoside price More Price(9)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich(India) | M3633 | 4-Methylumbelliferyl β-D-glucopyranoside β-glucosidase substrate | 18997-57-4 | 100MG | ₹7350.18 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | M3633 | 4-Methylumbelliferyl β-D-glucopyranoside β-glucosidase substrate | 18997-57-4 | 250MG | ₹14483.85 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | M3633 | 4-Methylumbelliferyl β-D-glucopyranoside β-glucosidase substrate | 18997-57-4 | 500MG | ₹25243.9 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | M3633 | 4-Methylumbelliferyl β-D-glucopyranoside β-glucosidase substrate | 18997-57-4 | 1G | ₹43061.85 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | M3633 | 4-Methylumbelliferyl β-D-glucopyranoside β-glucosidase substrate | 18997-57-4 | 5G | ₹133039.25 | 2022-06-14 | Buy |
4-Methylumbelliferyl-beta-D-glucopyranoside Chemical Properties,Uses,Production
Description
4-Methylumbelliferyl-β-D-Glucopyranoside (4-MUG) is a fluorogenic substrate of β-glucosidase and β-glucocerebrosidase (also known as glucosylceramidase). In addition to its use in characterizing novel β-glucosidases, 4-MUG is used in assays to evaluate deficiency in β- glucocerebrosidase activity related to Gaucher disease. Hydrolysis of 4-MUG releases the fluorescent product 4-MU, which has an emission maximum at 445-454 nm. The excitation maximum for 4-MU is pH-dependent: 330, 370, and 385 nm at pH 4.6, 7.4, and 10.4, respectively.
Chemical Properties
White Powder
Uses
A fluorogenic substrate in the assay of ?-glucosidase. Fluorescence: max. Abs. 316nm; max. Em. 372nm; e x 10-3: 15
Definition
ChEBI: A beta-D-glucoside having a 4-methylumbelliferyl substituent at the anomeric position.
Purification Methods
4-Methylumbellifer-7-yl--Dglucopyranoside crystallises as the half hydrate from hot H2O. [Constantzas & Kocourek Collect Czech Chem Commun 24 1099 1959, De Re et al. Ann Chim (Rome) 4 9 2089 1959, Courtin-Duchateau & Veyrière Carbohydr Research 65 23, 29 1978, Beilstein 18 III/IV 5152, 8 IV 433, 18/7 V 616.]
4-Methylumbelliferyl-beta-D-glucopyranoside Preparation Products And Raw materials
Raw materials
Preparation Products
Supplier | Tel | Country | ProdList | Advantage | Inquiry |
---|---|---|---|---|---|
CHEMSWORTH | +91-261-2397244 | New Delhi, India | 6707 | 30 | Inquiry |
CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6351 | 58 | Inquiry |
A.J Chemicals | 91-9810153283 | New Delhi, India | 6124 | 58 | Inquiry |
TCI Chemicals (India) Pvt. Ltd. | 1800 425 7889 | New Delhi, India | 6778 | 58 | Inquiry |
Triveni chemicals | 08048762458 | New Delhi, India | 6093 | 58 | Inquiry |
Reax Chemicals | 08048372701Ext 416 | Hyderabad, India | 4223 | 58 | Inquiry |
Sisco Research Laboratories Pvt. Ltd. | +91-22-4268 5800 | Mumbai, India | 4317 | 58 | Inquiry |
Siri Organics | 08985670323 | Hyderabad, India | 54 | 58 | Inquiry |
VASIN BIO LIFE SCIENCES PVT LTD | 9491644688 | Hyderabad, India | 2096 | 58 | Inquiry |
Anand Agencies | 91-20-24454597 | Maharashtra, India | 2337 | 58 | Inquiry |
Supplier | Advantage |
---|---|
CHEMSWORTH | 30 |
CLEARSYNTH LABS LTD. | 58 |
A.J Chemicals | 58 |
TCI Chemicals (India) Pvt. Ltd. | 58 |
Triveni chemicals | 58 |
Reax Chemicals | 58 |
Sisco Research Laboratories Pvt. Ltd. | 58 |
Siri Organics | 58 |
VASIN BIO LIFE SCIENCES PVT LTD | 58 |
Anand Agencies | 58 |
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