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PMPA(NAALADaseinhibitor)

PMPA(NAALADaseinhibitor) Structure
CAS No.
173039-10-6
Chemical Name:
PMPA(NAALADaseinhibitor)
Synonyms
2-PMPA;CS-2454;NAALADASEINHIBITOR;PMPA(NAALADaseinhibitor);2-PMPA(NAALADaseinhibitor);Pentanedioic acid, 2-(phosphonomethyl)-;2-(Phosphonomethyl)pentane-1,5-dioicacid;2-(PHOSPHONOMETHYL)PENTANEDIOIC ACID (PMPA);inhibit,Inhibitor,2PMPA,Carboxypeptidase,2-PMPA,2 PMPA
CBNumber:
CB91075110
Molecular Formula:
C6H11O7P
Molecular Weight:
226.12
MOL File:
173039-10-6.mol
MSDS File:
SDS
Modify Date:
2023/9/4 16:42:00
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PMPA(NAALADaseinhibitor) Properties

Boiling point 538.8±60.0 °C(Predicted)
Density 1.658±0.06 g/cm3(Predicted)
storage temp. room temp
solubility Soluble to 100 mM in sterile
pka 2.06±0.10(Predicted)
form powder
color white to beige
Water Solubility Soluble to 100 mM in water

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H315-H319
Precautionary statements  P305+P351+P338
RTECS  SA0454800
NFPA 704
0
2 0

PMPA(NAALADaseinhibitor) price More Price(2)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) SML1612 2-PMPA ≥98% (HPLC) 173039-10-6 5MG ₹12308.03 2022-06-14 Buy
Sigma-Aldrich(India) SML1612 2-PMPA ≥98% (HPLC) 173039-10-6 25MG ₹49578.5 2022-06-14 Buy
Product number Packaging Price Buy
SML1612 5MG ₹12308.03 Buy
SML1612 25MG ₹49578.5 Buy

PMPA(NAALADaseinhibitor) Chemical Properties,Uses,Production

Uses

2-(Phosphonomethyl)pentanedioic Acid is a selective glutamate carboxypeptidase 2 (GCP-II) inhibitor, the enzyme which catabolizes the abundant neuropeptide N-acetyl-aspartyl-glutamate (NAAG) to N-acetylaspartate (NAA) and glutamate. A posiible target in the treatment of multiple sclerosis and Schizophrenia.

Biological Activity

Highly potent and selective inhibitor of? glutamate carboxypeptidase 2 (GCP II/N-acetylated α -linked dipeptidase/NAALADase) with a K i value of 275 pM. Neuroprotective; protects against glutamate-mediated motor neuron degeneration and reduces volume of injury following middle cerebral artery occlusion (MCAO).

Biochem/physiol Actions

2-PMPA is a potent and selective inhibitor of Glutamate carboxypeptidase II (GCPII).

PMPA(NAALADaseinhibitor) Preparation Products And Raw materials

Raw materials

Preparation Products

PMPA(NAALADaseinhibitor) Suppliers

Global( 74)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
CHEMSWORTH +91-261-2397244 New Delhi, India 6707 30 Inquiry
ATK CHEMICAL COMPANY LIMITED +undefined-21-51877795 China 32835 60 Inquiry
Career Henan Chemica Co +86-0371-86658258 +8613203830695 China 30250 58 Inquiry
Zhejiang J&C Biological Technology Co.,Limited +1-2135480471 +1-2135480471 China 10522 58 Inquiry
Labnetwork lnc. +86-27-50766799 +8618062016861 China 19994 58 Inquiry
TargetMol Chemicals Inc. +1-781-999-5354 United States 19973 58 Inquiry
ShenZhen Trendseen Biological Technology Co.,Ltd. 13417589054 China 11681 58 Inquiry
LEAPCHEM CO., LTD. +86-852-30606658 China 43348 58 Inquiry
Aladdin Scientific +1-+1(833)-552-7181 United States 57511 58 Inquiry
Amadis Chemical Company Limited 571-89925085 China 131980 58 Inquiry
Supplier Advantage
CHEMSWORTH 30
ATK CHEMICAL COMPANY LIMITED 60
Career Henan Chemica Co 58
Zhejiang J&C Biological Technology Co.,Limited 58
Labnetwork lnc. 58
TargetMol Chemicals Inc. 58
ShenZhen Trendseen Biological Technology Co.,Ltd. 58
LEAPCHEM CO., LTD. 58
Aladdin Scientific 58
Amadis Chemical Company Limited 58

PMPA(NAALADaseinhibitor) Spectrum

PMPA(NAALADaseinhibitor)(173039-10-6)1HNMR

173039-10-6(PMPA(NAALADaseinhibitor))Related Search:

3-PHOSPHONOPROPIONIC ACID 5-PHOSPHONOPENTANOIC ACID PMPA(NAALADaseinhibitor)
PMPA(NAALADaseinhibitor) 2-(Phosphonomethyl)pentane-1,5-dioicacid 2-PMPA CS-2454 2-PMPA(NAALADaseinhibitor) NAALADASEINHIBITOR Pentanedioic acid, 2-(phosphonomethyl)- 2-(PHOSPHONOMETHYL)PENTANEDIOIC ACID (PMPA) inhibit,Inhibitor,2PMPA,Carboxypeptidase,2-PMPA,2 PMPA 173039-10-6