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5-Bromo-2-(trifluoromethoxy)aniline

5-Bromo-2-(trifluoromethoxy)aniline Structure
CAS No.
886762-08-9
Chemical Name:
5-Bromo-2-(trifluoromethoxy)aniline
Synonyms
5-Bromo-2-(trifluoromethoxy)aniline;5-Bromo-2-trifluoromethoxy-phenylamine;2-Amino-4-bromo-trfluoromethoxybenzene;3-Amino-4-(trifluoromethoxy)bromobenzene;Benzenamine, 5-bromo-2-(trifluoromethoxy)-;3-Amino-4-(trifluoromethoxy)bromobenzene98%
CBNumber:
CB91107309
Molecular Formula:
C7H5BrF3NO
Molecular Weight:
256.02
MOL File:
886762-08-9.mol
MSDS File:
SDS
Modify Date:
2023/4/23 13:52:06

5-Bromo-2-(trifluoromethoxy)aniline Properties

Boiling point 230.2±35.0 °C(Predicted)
Density 1.726±0.06 g/cm3(Predicted)
storage temp. Keep in dark place,Inert atmosphere,Room temperature
pka 1.38±0.10(Predicted)
form liquid
color Pale yellow

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS06
Signal word  Danger
Hazard statements  H315-H319-H335
Precautionary statements  P260-P271-P280
Hazard Codes  Xi
RIDADR  UN2811
HS Code  2922500090
NFPA 704
0
2 0

5-Bromo-2-(trifluoromethoxy)aniline Chemical Properties,Uses,Production

Description

5-Bromo-2-(trifluoromethoxy)aniline has a wide range of applications in scientific research. It is used as a reagent in organic synthesis and as a catalyst in polymerization reactions. It is also used as a building block for the synthesis of other organic compounds, such as pharmaceuticals and agrochemicals. It is also used in the synthesis of heterocyclic compounds and in the preparation of metal complexes.

Uses

5-Bromo-2-(trifluoromethoxy)aniline (5-BTA) is a drug with inhibitory activity against cell proliferation and has been shown to be effective in inhibiting the growth of certain cancer cells, such as those expressing tyrosine kinase isoforms. 5-BTA is also capable of blocking cell proliferation through inhibition of other enzymes (e.g., protein kinases). The oral Bioavailability of 5-BTA has been demonstrated in rats and mice. A2780 cells are human lung cancer cells with mutations in the gene encoding tyrosine kinase. Selectivity for tyrosine kinase isoforms was observed in vitro and in vivo.

5-Bromo-2-(trifluoromethoxy)aniline Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 161)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
JSK Chemicals +919879767970 Gujarat, India 3756 58 Inquiry
A.J Chemicals 91-9810153283 New Delhi, India 6124 58 Inquiry
CLEARSYNTH LABS LTD. +91-22-45045900 Hyderabad, India 6351 58 Inquiry
Capot Chemical Co.,Ltd. 571-85586718 +8613336195806 China 29798 60 Inquiry
ATK CHEMICAL COMPANY LIMITED +undefined-21-51877795 China 32760 60 Inquiry
Shanghai Worldyang Chemical Co.,Ltd. +86-021-56795779 +8613651600618 China 1080 58 Inquiry
CONIER CHEM AND PHARMA LIMITED +8618523575427 China 49391 58 Inquiry
career henan chemical co +86-0371-86658258 +8613203830695 China 29826 58 Inquiry
Shaanxi Dideu Medichem Co. Ltd +86-29-87569265 +86-18612256290 China 2132 58 Inquiry
Fuxin Pharmaceutical +86-021-021-50872116 +8613122107989 China 10297 58 Inquiry

5-Bromo-2-(trifluoromethoxy)aniline Spectrum

3-Amino-4-(trifluoromethoxy)bromobenzene98% 3-Amino-4-(trifluoromethoxy)bromobenzene 2-Amino-4-bromo-trfluoromethoxybenzene Benzenamine, 5-bromo-2-(trifluoromethoxy)- 5-Bromo-2-trifluoromethoxy-phenylamine 5-Bromo-2-(trifluoromethoxy)aniline 886762-08-9 Fluorine series