8-Hydroxyquinoline-N-oxide
- CAS No.
- 1127-45-3
- Chemical Name:
- 8-Hydroxyquinoline-N-oxide
- Synonyms
- NSC 21656; NSC 2165;2-METHYLOXINE;OXINE N-OXIDE;1-Oxy-quinolin-8-ol;TIMTEC-BB SBB009099;8-Hydroxyquinoline-N;8-QUINOLINOL-1-OXIDE;8-QUINOLINOL N-OXIDE;Quinolin-8-ol N-oxide
- CBNumber:
- CB9112579
- Molecular Formula:
- C9H7NO2
- Molecular Weight:
- 161.16
- MOL File:
- 1127-45-3.mol
- MSDS File:
- SDS
- Modify Date:
- 2023/6/19 22:07:12
| Melting point | 135-138 °C (lit.) |
|---|---|
| Boiling point | 267 °C(lit.) |
| Density | 1.2480 (rough estimate) |
| refractive index | 1.5050 (estimate) |
| Flash point | 139 °C |
| storage temp. | Inert atmosphere,2-8°C |
| solubility | Soluble in Acetone, Chloroform, Dichloromethane, Ethyl Acetate and Methanol |
| form | Solid |
| pka | 6.03±0.30(Predicted) |
| color | Yellow |
| BRN | 128737 |
| CAS DataBase Reference | 1127-45-3(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS08 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H317-H351b-H372 | |||||||||
| Precautionary statements | P201-P202-P260-P264b-P270-P272-P280g-P302+P352-P308+P313-P363-P403-P501c | |||||||||
| Hazard Codes | N,Xi | |||||||||
| Risk Statements | 50/53-36/37/38 | |||||||||
| Safety Statements | 60-61-24/25-22-36/37/39-27-26 | |||||||||
| RIDADR | UN 3077 9/PG 3 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | VC8238500 | |||||||||
| F | 3-10 | |||||||||
| HS Code | 29334900 | |||||||||
| NFPA 704 |
|
8-Hydroxyquinoline-N-oxide price More Price(6)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 122335 | 8-Quinolinol N-oxide 98% | 1127-45-3 | 5G | ₹9740 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | 122335 | 8-Quinolinol N-oxide 98% | 1127-45-3 | 5G | ₹9740 | 2022-06-14 | Buy |
| Sigma-Aldrich | 122335 | 8-Quinolinol N-oxide 98% | 1127-45-3 | 10G | ₹19970 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | 122335 | 8-Quinolinol N-oxide 98% | 1127-45-3 | 10G | ₹19970 | 2022-06-14 | Buy |
| TCI Chemicals (India) | H1272 | 8-Hydroxyquinoline N-Oxide | 1127-45-3 | 5G | ₹6900 | 2022-05-26 | Buy |
8-Hydroxyquinoline-N-oxide Chemical Properties,Uses,Production
Description
A quinoline derivative that displays mutagenic activity. It suppresses luminescence of an indicator bacterium that is named Photobacterium phosphoreum. This chemical forms two kinds of complexes with palladium (II) and Gold (III). One kind is an ion-associated compound containing hydrogen bond and hte other is the six membered metal chelates containing metal-oxygen bonds.
Chemical Properties
Yellow Crystalline Solid
General Description
8-Quinolinol N-oxide is a toxicant which can suppress luminescence of an indicator bacterium Photobacterium phosphoreum. It forms two types of complexes with gold(III) and palladium(II): type I are ion-associated compounds containing hydrogen bond and the other is the six-membered metal chelates containing metal-oxygen bonds.
Synthesis
8-hydroxyquinoline-N-oxide was synthesized from 8-hydroxyquinoline. A stirred solution of 8-hydroxyquinoline (25.00 g, 172.2 mmol) in 550 ml of CHCl3 was cooled to 0° C., and 3 -chloroperoxybenzoic acid (40.00 g, 80% Tech. grade *0.231 mmol=0.185 mmol) was added slowly over 3 minutes. The solution was kept at 0° C. and stirred for 3 hours. During this period, the 3-chlorobenzoic acid byproduct precipitated. The 3-chlorobenzoic acid was removed by filtration and the orange filtrate was concentrated to dryness and the remaining solid was triturated with 2% NH40 H (2*200 ml). The solid was isolated on a frit and washed with H2O.
8-Hydroxyquinoline-N-oxide Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| CHEMSWORTH | +91-261-2397244 | New Delhi, India | 6707 | 30 | Inquiry |
| A.J Chemicals | 91-9810153283 | New Delhi, India | 6124 | 58 | Inquiry |
| TCI Chemicals (India) Pvt. Ltd. | 1800 425 7889 | New Delhi, India | 6778 | 58 | Inquiry |
| Dhruvtara Chemicals Pvt. Ltd. | 91 40 27154607 | New Delhi, India | 180 | 56 | Inquiry |
| Oceanic Pharmachem Pvt., Ltd. (OPPL) | 91-22-42128600 | Maharashtra, India | 947 | 58 | Inquiry |
| Vyas Bio Life Sciences Pvt. Ltd | -65546373 | Hyderabad, India | 1213 | 58 | Inquiry |
| CAD Pharma Inc. | 91-80-41536439 | Karnataka, India | 123 | 58 | Inquiry |
| Dhruvtara Chemicals Private Limited | 08048361362Ext 107 | Hyderabad, India | 84 | 58 | Inquiry |
| Nanjing Triumpharm Co.,Ltd | +86-02586182925 +86-15105172550 | China | 129 | 58 | Inquiry |
| Henan Bao Enluo International TradeCo.，LTD | +86-17331933971 +86-17331933971 | China | 2503 | 58 | Inquiry |
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