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Chebulinic acid

Chebulinic acid Structure
CAS No.
18942-26-2
Chemical Name:
Chebulinic acid
Synonyms
Eutannin;NSC69862;CHEBULINIC ACID;CHEBULINIC ACID(SH);CHEBULINIC ACID USP/EP/BP;Chebulinic acid >=85% (LC/MS-ELSD);b-D-Glucopyranose,1,3,6-tris(3,4,5-trihydroxybenzoate), cyclic 22:41-ester with (2S)-[(3R,4S)-5-carboxy-3,4-dihydro-3,7,8-trihydroxy-2-oxo-2H-1-benzopyran-4-yl]butanedioicacid;β-D-Glucopyranose, 1,3,6-tris(3,4,5-trihydroxybenzoate), cyclic 2→2:4→1-ester with (2S)-[(3R,4S)-5-carboxy-3,4-dihydro-3,7,8-trihydroxy-2-oxo-2H-1-benzopyran-4-yl]butanedioic acid;β-D-Glucopyranose, 1,3,6-tris(3,4,5-trihydroxybenzoate), cyclic 2→2:4→1-ester with (2S)-[(3R,4S)-5-carboxy-3,4-dihydro-3,7,8-trihydroxy-2-oxo-2H-1-benzopyran-4-yl]butanedioic acid;2-((3R,3aS,4S,7R,8R,10S,11R,17R)-3,15,16-Trihydroxy-2,5,13-trioxo-10,17-bis((3,4,5-trihydroxybenzoyl)oxy)-8-(((3,4,5-trihydroxybenzoyl)oxy)methyl)-2,3,3a,4,5,7,8,10,11,13-decahydro-7,11-methano[1,4,7]trioxacyclotridecino[11,10,9-de]chromen-4-yl)acetic acid
CBNumber:
CB9139286
Molecular Formula:
C41H32O27
Molecular Weight:
956.68
MOL File:
18942-26-2.mol
Modify Date:
2024/2/6 13:42:11

Chebulinic acid Properties

Boiling point 1460.0±65.0 °C(Predicted)
Density 2.04
storage temp. -20°C
solubility Soluble in acetone, methanol and hot water; insoluble in chloroform and n-hexane
form powder
pka 4.14±0.10(Predicted)
color Beige
InChIKey YGVHOSGNOYKRIH-KOPSEHRPNA-N

SAFETY

Risk and Safety Statements

WGK Germany  3

Chebulinic acid price More Price(2)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) SMB00271 Chebulinic acid ≥85% (LC/MS-ELSD) 18942-26-2 1MG ₹39175.68 2022-06-14 Buy
Sigma-Aldrich(India) 40820 Chebulinic acid analytical standard 18942-26-2 10MG ₹68251.63 2022-06-14 Buy
Product number Packaging Price Buy
SMB00271 1MG ₹39175.68 Buy
40820 10MG ₹68251.63 Buy

Chebulinic acid Chemical Properties,Uses,Production

Uses

Chebulinic Acid has been shown to prevent epithelial mesenchymal transition in retinal pigment epithelial cells through inhibition of SMAD-3 phosphorylation. This prevents retinal detachment in the process of proliferative vitreoretinopathy.

Origin

Chebulinic acid, an ellagitannin found commonly in Terminalia chebula, has been used extensively to treat diverse eras of ailments traditionally. It was also present in Phyllanthus emblica, Dimocarpus longan, Terminalia catappa, Terminalia parviflora, Terminalia macroptera, Lumnttzera racemosa, and Dendrophthoe falcate and has been used extensively in the traditional Indian system of medicine. It was first isolated by Fridolin in the year 1884[1].

Chebulinic acid Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 130)Suppliers
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CHEBULINIC ACID NSC69862 CHEBULINIC ACID(SH) Eutannin β-D-Glucopyranose, 1,3,6-tris(3,4,5-trihydroxybenzoate), cyclic 2→2:4→1-ester with (2S)-[(3R,4S)-5-carboxy-3,4-dihydro-3,7,8-trihydroxy-2-oxo-2H-1-benzopyran-4-yl]butanedioic acid b-D-Glucopyranose,1,3,6-tris(3,4,5-trihydroxybenzoate), cyclic 22:41-ester with (2S)-[(3R,4S)-5-carboxy-3,4-dihydro-3,7,8-trihydroxy-2-oxo-2H-1-benzopyran-4-yl]butanedioicacid Chebulinic acid >=85% (LC/MS-ELSD) CHEBULINIC ACID USP/EP/BP β-D-Glucopyranose, 1,3,6-tris(3,4,5-trihydroxybenzoate), cyclic 2→2:4→1-ester with (2S)-[(3R,4S)-5-carboxy-3,4-dihydro-3,7,8-trihydroxy-2-oxo-2H-1-benzopyran-4-yl]butanedioic acid 2-((3R,3aS,4S,7R,8R,10S,11R,17R)-3,15,16-Trihydroxy-2,5,13-trioxo-10,17-bis((3,4,5-trihydroxybenzoyl)oxy)-8-(((3,4,5-trihydroxybenzoyl)oxy)methyl)-2,3,3a,4,5,7,8,10,11,13-decahydro-7,11-methano[1,4,7]trioxacyclotridecino[11,10,9-de]chromen-4-yl)acetic acid 18942-26-2 C41H34O28 C41H32O27