3-Fluoro-4-nitrobenzoic acid
- CAS No.
- 403-21-4
- Chemical Name:
- 3-Fluoro-4-nitrobenzoic acid
- Synonyms
- BUTTPARK 32\01-75;3-Fluoro-4-nitrobenzoic;uoro-4-nitrobenzoic Acid;3-FLUORO-4-NITROBENZONICACID;3-FLUORO-4-NITROBENZOIC ACID;3-FLUORO-4-NITROBENZOIC CAID;3-Fluoro-4-nitrobenzoicacid95%;3-Fluoro-4-nitrobenzoicacid99%;4-Carboxy-2-fluoronitrobenzene;3-Fluoro-4-nitrobenzoicAcid>
- CBNumber:
- CB9155507
- Molecular Formula:
- C7H4FNO4
- Molecular Weight:
- 185.11
- MOL File:
- 403-21-4.mol
- MSDS File:
- SDS
- Modify Date:
- 2023/7/26 16:38:48
| Melting point | 174-175°C |
|---|---|
| Boiling point | 372.8±27.0 °C(Predicted) |
| Density | 1.568±0.06 g/cm3(Predicted) |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | soluble in Methanol |
| form | powder to crystal |
| pka | 3.08±0.10(Predicted) |
| color | White to Light yellow to Green |
| InChI | InChI=1S/C7H4FNO4/c8-5-3-4(7(10)11)1-2-6(5)9(12)13/h1-3H,(H,10,11) |
| InChIKey | WVZBIQSKLXJFNX-UHFFFAOYSA-N |
| SMILES | C(O)(=O)C1=CC=C([N+]([O-])=O)C(F)=C1 |
| CAS DataBase Reference | 403-21-4(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P280a-P304+P340-P305+P351+P338-P405-P501a | |||||||||
| Hazard Codes | Xi,Xn | |||||||||
| Risk Statements | 36/37/38-37/38-36-22 | |||||||||
| Safety Statements | 26-36/37/39-37 | |||||||||
| HazardClass | IRRITANT | |||||||||
| HS Code | 29163990 | |||||||||
| NFPA 704 |
|
3-Fluoro-4-nitrobenzoic acid price More Price(4)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TCI Chemicals (India) | F0670 | 3-Fluoro-4-nitrobenzoic Acid min. 98.0 % | 403-21-4 | 5G | ₹10000 | 2022-05-26 | Buy |
| TCI Chemicals (India) | F0670 | 3-Fluoro-4-nitrobenzoic Acid min. 98.0 % | 403-21-4 | 25G | ₹20800 | 2022-05-26 | Buy |
| ALFA India | ALF-H26168-06 | 3-Fluoro-4-nitrobenzoic acid, 98+% | 403-21-4 | 5g | ₹9202 | 2022-05-26 | Buy |
| ALFA India | ALF-H26168-03 | 3-Fluoro-4-nitrobenzoic acid, 98+% | 403-21-4 | 1g | ₹4284 | 2022-05-26 | Buy |
3-Fluoro-4-nitrobenzoic acid Chemical Properties,Uses,Production
Uses
3-Fluoro-4-nitrobenzoic Acid is used in the synthesis of ABT-072, a non-nucleoside HCV NS5B polymerase inhibitor.
Synthesis
To a solution of 3-fluoro-4-nitrobenzyl alcohol (2.97 g) in acetone (60 ml) was added Jones reagent (13 ml), prepared from chromic acid (26.7 g) and sulfuric acid (23 ml) in water (100 ml), dropwise at 0°C. The mixture was stirred on a ice-bath for 0.5 h and quenched with isopropanol (20 ml) to be concentrated in vacuo. The residue was dissolved in ethyl acetate (30 ml) and washed with water (30 ml X 3), and brine (30 ml X 1), successively. The organic layer was dried over sodium sulfate and concentrated in vacuo to obtain a yellow solid, that was triturated with hexane. 3-fluoro-4-nitrobenzoic acid as a pale yellow solid (2.94 g, 92%).
3-Fluoro-4-nitrobenzoic acid Preparation Products And Raw materials
Raw materials
Preparation Products
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Global( 305)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| ALS INDIA LIFE SCIENCES | +91-8977036379 +91-8977036379 | Hyderabad, India | 1879 | 58 | Inquiry |
| M M Kemicals | +91-7032683572 +91-9989927761 | Telangana, India | 38 | 58 | Inquiry |
| Synthetic Research Pharma Laboratories Pvt Ltd | +91 9848023377 | Hyderabad, India | 116 | 58 | Inquiry |
| Prodev Pharma Pvt Ltd | +91-9963029529 +91-9043422844 | Telangana, India | 102 | 58 | Inquiry |
| SL Drugs and Pharmaceuticals Pvt. Ltd. | +91 (40) 6661-1133 | New Delhi, India | 2688 | 50 | Inquiry |
| CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6351 | 58 | Inquiry |
| A.J Chemicals | 91-9810153283 | New Delhi, India | 6124 | 58 | Inquiry |
| TCI Chemicals (India) Pvt. Ltd. | 1800 425 7889 | New Delhi, India | 6778 | 58 | Inquiry |
| Alfa Aesar | 1 800 209 7001 | Maharashtra, India | 6913 | 58 | Inquiry |
| Inventous Organics | 08046030057 | Mumbai, India | 67 | 58 | Inquiry |
| Supplier | Advantage |
|---|---|
| ALS INDIA LIFE SCIENCES | 58 |
| M M Kemicals | 58 |
| Synthetic Research Pharma Laboratories Pvt Ltd | 58 |
| Prodev Pharma Pvt Ltd | 58 |
| SL Drugs and Pharmaceuticals Pvt. Ltd. | 50 |
| CLEARSYNTH LABS LTD. | 58 |
| A.J Chemicals | 58 |
| TCI Chemicals (India) Pvt. Ltd. | 58 |
| Alfa Aesar | 58 |
| Inventous Organics | 58 |
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3-FLUORO-4-NITROBENZENECARBOXYLIC ACID
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BUTTPARK 32\01-75
3-FLUORO-4-NITROBENZONICACID
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3-Fluoro-4-nitrobenzoicAcid>
Benzoic acid, 3-fluoro-4-nitro-
uoro-4-nitrobenzoic Acid
3-FLUORO-4-NITROBENZOIC CAID
403-21-4
403-21-1
Carboxylic Acids
Phenyls & Phenyl-Het
Aromatic Carboxylic Acids, Amides, Anilides, Anhydrides & Salts
Miscellaneous
blocks
Carboxes
FluoroCompounds
NitroCompounds
Acids and Derivatives