CHEMBRDG-BB 5280909

CHEMBRDG-BB 5280909 Structure
CAS No.
89159-60-4
Chemical Name:
CHEMBRDG-BB 5280909
Synonyms
ML-354;CHEMBRDG-BB 5280909;1-Methyl-5-nitro-3-phenyl-1H-indole-2-methanol;1H-Indole-2-methanol, 1-methyl-5-nitro-3-phenyl-;(1-METHYL-5-NITRO-3-PHENYL-1H-INDOL-2-YL)METHANOL;(1-methyl-5-nitro-3-phenyl-1H-indol-2-yl)methanol(SALTDATA: FREE)
CBNumber:
CB9163102
Molecular Formula:
C16H14N2O3
Molecular Weight:
282.29
MOL File:
89159-60-4.mol
MSDS File:
SDS
Modify Date:
2023/6/30 15:45:59

CHEMBRDG-BB 5280909 Properties

Melting point 178-179 °C(Solv: 1,4-dioxane (123-91-1))
Boiling point 544.0±50.0 °C(Predicted)
Density 1.29±0.1 g/cm3(Predicted)
storage temp. -20°C
solubility ≤2mg/ml in ethanol;20mg/ml in DMSO;20mg/ml in dimethyl formamide
form powder
pka 14.47±0.10(Predicted)
color white to beige

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS06
Signal word  Danger
Hazard statements  H301
Precautionary statements  P301+P310
RIDADR  UN 2811 6.1 / PGIII
NFPA 704
0
2 0

CHEMBRDG-BB 5280909 Chemical Properties,Uses,Production

Description

ML-354 is an indole-based, proteinase-activated receptor 4 (PAR4) antagonist (IC50 = 140 nM) that exhibits 71-fold selectivity for PAR4 over PAR1 (IC50 = 10 μM) in isolated human platelets.

Uses

ML-354 is a selective protease activated receptor 4 ( PAR-4) antagonist used for its antithrombotic effects.

Biochem/physiol Actions

ML354 is a potent and selective PAR4 (protease activated receptor-4) antagonist.

CHEMBRDG-BB 5280909 Preparation Products And Raw materials

Raw materials

Preparation Products

CHEMBRDG-BB 5280909 Suppliers

Global( 34)Suppliers
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Wuhan Topule Biopharmaceutical Co., Ltd +8618327326525 China 8474 58 Inquiry
Aladdin Scientific +1-+1(833)-552-7181 United States 52927 58 Inquiry
RD International Technology Co., Limited 18024082417 China 9155 58 Inquiry
Shanghai EFE Biological Technology Co., Ltd. 021-65675885 18964387627 China 9708 58 Inquiry
ChemBridge Corporation (858)451-7400 United States 6650 70 Inquiry
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Riedel-de Haen AG 800 558-9160 United States 6825 87 Inquiry
Tocris Bioscience +44 (0) 117 916 3333 United Kingdom 5729 77 Inquiry
United States Biological 1-800-520-3011 United States 6106 58 Inquiry
ApexBio Technology + 1-832-696-8203 United States 6254 58 Inquiry
CHEMBRDG-BB 5280909 (1-METHYL-5-NITRO-3-PHENYL-1H-INDOL-2-YL)METHANOL (1-methyl-5-nitro-3-phenyl-1H-indol-2-yl)methanol(SALTDATA: FREE) ML-354 1-Methyl-5-nitro-3-phenyl-1H-indole-2-methanol 1H-Indole-2-methanol, 1-methyl-5-nitro-3-phenyl- 89159-60-4