2,4,7-TRINITRO-9-FLUORENONE

2,4,7-TRINITRO-9-FLUORENONE Structure
CAS No.
129-79-3
Chemical Name:
2,4,7-TRINITRO-9-FLUORENONE
Synonyms
TNF;mTNF-α;tnf(ketone);TRINITROFLUORENONE;LABOTEST-BB LT00645370;2,4,7-trinitrofluorone;2,4,7-Trinirofluorenone;2,4,7-TRINITROFLUORENONE;2,4,7-Trinitrofluoren-9-one;2,4,7-trinitro-fluoren-9-on
CBNumber:
CB9210251
Molecular Formula:
C13H5N3O7
Molecular Weight:
315.19
MOL File:
129-79-3.mol
Modify Date:
2023/4/23 13:52:06

2,4,7-TRINITRO-9-FLUORENONE Properties

Melting point 176-178°C
Boiling point 454.77°C (rough estimate)
Density 1.5148 (rough estimate)
refractive index 1.5600 (estimate)
storage temp. -20°C
form powder
color white
CAS DataBase Reference 129-79-3(CAS DataBase Reference)
EPA Substance Registry System 2,4,7-Trinitrofluoren-9-one (129-79-3)

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H315-H319
Precautionary statements  P264-P280-P302+P352-P305+P351+P338-P332+P313-P337+P313
Risk Statements  23/24/25-33
Safety Statements  9-16-36/37/39
RIDADR  387
WGK Germany  3
HazardClass  1.1D
PackingGroup  II
Toxicity LD50 oral in rat: 9910mg/kg

2,4,7-TRINITRO-9-FLUORENONE price More Price(5)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) T7539 Tumor Necrosis Factor-α from mouse TNF-α, recombinant, expressed in E. coli, powder, suitable for cell culture 129-79-3 10μG ₹25818.6 2022-06-14 Buy
Sigma-Aldrich(India) T7539 Tumor Necrosis Factor-α from mouse TNF-α, recombinant, expressed in E. coli, powder, suitable for cell culture 129-79-3 50μG ₹68786.7 2022-06-14 Buy
Sigma-Aldrich(India) T5944 Tumor Necrosis Factor-α from rat TNF-α, recombinant, expressed in E. coli, powder, suitable for cell culture 129-79-3 10μG ₹29448.3 2022-06-14 Buy
Sigma-Aldrich(India) T5944 Tumor Necrosis Factor-α from rat TNF-α, recombinant, expressed in E. coli, powder, suitable for cell culture 129-79-3 50μG ₹68786.7 2022-06-14 Buy
Sigma-Aldrich(India) SAB4502982 Anti-TNFA antibody produced in rabbit affinity isolated antibody 129-79-3 100μG ₹50560.5 2022-06-14 Buy
Product number Packaging Price Buy
T7539 10μG ₹25818.6 Buy
T7539 50μG ₹68786.7 Buy
T5944 10μG ₹29448.3 Buy
T5944 50μG ₹68786.7 Buy
SAB4502982 100μG ₹50560.5 Buy

2,4,7-TRINITRO-9-FLUORENONE Chemical Properties,Uses,Production

Uses

Tumor Necrosis Factor-α from mouse, a potent proinflammatory cytokine has been used:

  • to activate MS1 endothelium cells
  • to induce lipolysis in adipocytes
  • to study its effect on liganded and unliganded glucocorticoid receptor (GR) in interleukin (IL)-6 and IL-8 gene regulation

General Description

Pale yellow needles (from acetic acid or benzene) or yellow powder.

Air & Water Reactions

Insoluble in water.

Reactivity Profile

Literature sources indicate that 2,4,7-TRINITRO-9-FLUORENONE is flammable. . Aromatic nitrates range from slight to strong oxidizing agents. If mixed with reducing agents, including hydrides, sulfides and nitrides, they may begin a vigorous reaction.

Hazard

Suspected carcinogen. Mildly toxic by ingestion. A skin and eye irritant.

Fire Hazard

Literature sources indicate that 2,4,7-TRINITRO-9-FLUORENONE is flammable.

Safety Profile

Suspected carcinogen with experimental tumorigenic data. Mildly toxic by ingestion. Human mutation data reported. A skin and eye irritant. When heated to decomposition it emits hghly toxic fumes of NOx. See also NITRO COMPOUNDS of AROMATIC HYDROCARBONS and KETONES.

Purification Methods

Crystallise it from nitric acid/water (3:1), wash it with water and dry it under vacuum over P2O5, or recrystallise it from dry *benzene. [Beilstein 7 II 410, 7 III 2348, 7 IV 1638.]

2,4,7-TRINITRO-9-FLUORENONE Preparation Products And Raw materials

Raw materials

Preparation Products

2,4,7-trinitro-9h-fluoren-9-on 2,4,7-Trinitro-9H-fluoren-9-one 2,4,7-trinitro-fluoren-9-on 2,4,7-trinitrofluorone 9-fluorenone,2,4,7-trinitro- 9H-Fluoren-9-one, 2,4,7-trinitro- Fluoren-9-one, 2,4,7-trinitro- TNF tnf(ketone) LABOTEST-BB LT00645370 2,4,7-Trinitrofluoren-9-one 2,4,7-TRINITROFLUORENONE 2,4,7-TRINITRO-9-FLUORENONE 2,4,-TRINITRO-9-FLUORENONE (100UG/ML IN TOLUENE) 2,4,7-Trinitro-9-fluorenone (wetted with ca. 20% Water, containing 5g 2,4,7-Trinirofluorenone 2,4,7-TRINITRO-9-FLUORENONE(WETTEDWITHCA.20%WATER,CONTAINING5GONADRYWEIGHTBASIS) TRINITROFLUORENONE mTNF-α Tumor Necrosis Factor-α from mouse Tumor necrosis factor ligand superfamily member 2 Tumor Necrosis Factor-α from rat 2,4,7-Trinitro-9-fluorenone (wetted with ca. 20% Water) (unit weight on dry weight basis) Recombinant Human TNF Protein, His Tag Recombinant Human TNFa/TNFSF2/TNF Protein, No Tag Recombinant Human TNF-alpha N-His Protein, His Tag Recombinant Human TNF-alpha Protein, His Tag Anti-TNFA antibody produced in rabbit 129-79-3 C13H5N3O7 Fluorenes, Flurenones