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DCPIB

DCPIB Structure
CAS No.
82749-70-0
Chemical Name:
DCPIB
Synonyms
DCPIB;4-(2-BUTYL-6,7-DICHLORO-2-CYCLOPENTYLINDAN-1-ON-5-YL)OXYBUTYRIC ACID;4-(2-butyl-6,7-dichlor-2-cyclopentyl-indan-1-on-5-yl) oxybutyric acid;4-[(2-Butyl-6,7-dichloro-2-cyclopentyl-1-oxo-5-indanyl)oxy]butanoic Acid;4-[(2-BUTYL-6,7-DICHLORO-2-CYCLOPENTYL-2,3-DIHYDRO-1-OXO-1H-INDEN-5-YL)OXY]BUTANOIC ACID;Butanoic acid, 4-[(2-butyl-6,7-dichloro-2-cyclopentyl-2,3-dihydro-1-oxo-1H-inden-5-yl)oxy]-;Cl-Channels,Chloride Channel,cardiomyocytes,DCPIB,ischemia,COS-7,KcsA,Potassium Channel,CPAE cell,Inhibitor,inhibit,swelling,rMCAO
CBNumber:
CB9215009
Molecular Formula:
C22H28Cl2O4
Molecular Weight:
427.36
MOL File:
82749-70-0.mol
Modify Date:
2023/6/30 15:45:59
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DCPIB Properties

Boiling point 593.8±50.0 °C(Predicted)
Density 1.262±0.06 g/cm3(Predicted)
storage temp. Store at +4°C
solubility insoluble in H2O; ≥49.8 mg/mL in EtOH; ≥50.8 mg/mL in DMSO
pka 4.53±0.10(Predicted)
form solid
color White

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS05,GHS06
Signal word  Danger
Hazard statements  H301-H413-H318
Precautionary statements  P280-P305+P351+P338-P310-P264-P270-P301+P310-P321-P330-P405-P501
Hazard Codes  T
Risk Statements  25-41
Safety Statements  26-36/39-45
NFPA 704
0
3 0

DCPIB Chemical Properties,Uses,Production

Uses

DCPIB is a potent, selective blocker of the volume-sensitive anion channel (VSAC) in rat pancreatic β-cells.

Biological Activity

Potent, selective blocker of the volume-sensitive anion channel (VSAC) in rat pancreatic β -cells (IC 50 ~ 2 μ M) and I Cl,swell in various cardiovascular tissues (IC 50 = 4.1 μ M in CPAE cells); blockade is voltage-independent. Displays minimal inhibition of other Cl - and K + currents (< 10% inhibition at 10 μ M). Inhibits glucose-stimulated insulin secretion in intact β -cells via VSAC inhibition and indirect K ATP channel activation. Reverses cell swelling-induced action potential duration shortening in atrial myocytes and inhibits astroglial swelling in vitro .

DCPIB Preparation Products And Raw materials

Raw materials

Preparation Products

DCPIB Suppliers

Global( 58)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
BOC Sciences +1-631-485-4226 United States 19553 58 Inquiry
TargetMol Chemicals Inc. +1-781-999-5354 +1-00000000000 United States 19892 58 Inquiry
Career Henan Chemica Co +86-0371-86658258 +8613203830695 China 30253 58 Inquiry
InvivoChem +1-708-310-1919 +1-13798911105 United States 6393 58 Inquiry
Nanjing Doge Biomedical Technology Co., Ltd +86-25-58227606 +86-15305155328 China 4128 58 Inquiry
Hangzhou MolCore BioPharmatech Co.,Ltd. +86-057181025280; +8617767106207 China 49739 58 Inquiry
LEAPCHEM CO., LTD. +86-852-30606658 China 43348 58 Inquiry
Aladdin Scientific +1-+1(833)-552-7181 United States 57511 58 Inquiry
Shanghai Aladdin Biochemical Technology Co.,Ltd. +86-18521732826 China 48467 58 Inquiry
Shanghai Chaolan Chemical Technology Center QQ:65489617 15618227136 China 9874 58 Inquiry
Supplier Advantage
BOC Sciences 58
TargetMol Chemicals Inc. 58
Career Henan Chemica Co 58
InvivoChem 58
Nanjing Doge Biomedical Technology Co., Ltd 58
Hangzhou MolCore BioPharmatech Co.,Ltd. 58
LEAPCHEM CO., LTD. 58
Aladdin Scientific 58
Shanghai Aladdin Biochemical Technology Co.,Ltd. 58
Shanghai Chaolan Chemical Technology Center 58

DCPIB Spectrum

DCPIB(82749-70-0)MS

82749-70-0(DCPIB)Related Search:

2,3-Dichloro-4-hydroxybenzaldehyde 6-CHLORO-1-INDANONE 96 7-CHLORO-1-INDANONE 2-CHLORO-4,5-DIMETHYLPHENOL 4-(3-CHLORO-PHENOXY)-BUTYRIC ACID
2'-CHLORO-2,2-DIMETHYLBUTYROPHENONE 2',3'-DICHLORO-2,2-DIMETHYLBUTYROPHENONE 2-PENTYL-1-INDANONE 1-(3-chloro-4-ethoxyphenyl)ethanone DCPIB
1-(3-CHLORO-4-PROPOXYPHENYL)-ETHANONE 3'-CHLORO-2,2-DIMETHYLBUTYROPHENONE 2'-CHLORO-2,2-DIMETHYLPROPIOPHENONE 2',3'-DICHLORO-2,2-DIMETHYLPROPIOPHENONE 2,2-DIMETHYL-4'-METHOXYBUTYROPHENONE
4-(4-ACETYL-PHENOXY)-BUTYRIC ACID 1-(4-methoxyphenyl)-2,2-dimethyl-propan-1-one 3'-CHLORO-2,2-DIMETHYLPROPIOPHENONE
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DCPIB 4-[(2-BUTYL-6,7-DICHLORO-2-CYCLOPENTYL-2,3-DIHYDRO-1-OXO-1H-INDEN-5-YL)OXY]BUTANOIC ACID 4-(2-BUTYL-6,7-DICHLORO-2-CYCLOPENTYLINDAN-1-ON-5-YL)OXYBUTYRIC ACID Butanoic acid, 4-[(2-butyl-6,7-dichloro-2-cyclopentyl-2,3-dihydro-1-oxo-1H-inden-5-yl)oxy]- Cl-Channels,Chloride Channel,cardiomyocytes,DCPIB,ischemia,COS-7,KcsA,Potassium Channel,CPAE cell,Inhibitor,inhibit,swelling,rMCAO 4-(2-butyl-6,7-dichlor-2-cyclopentyl-indan-1-on-5-yl) oxybutyric acid 4-[(2-Butyl-6,7-dichloro-2-cyclopentyl-1-oxo-5-indanyl)oxy]butanoic Acid 82749-70-0 Chloride channel