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(2-METHOXY-5-[2-(2,4,6-TRIMETHOXY-PHENYL)-ETHENESULFONYLMETHYL]-PHENYLAMINO)-ACETIC ACID, SODIUM SALT

(2-METHOXY-5-[2-(2,4,6-TRIMETHOXY-PHENYL)-ETHENESULFONYLMETHYL]-PHENYLAMINO)-ACETIC ACID, SODIUM SALT Structure
CAS No.
592542-59-1
Chemical Name:
(2-METHOXY-5-[2-(2,4,6-TRIMETHOXY-PHENYL)-ETHENESULFONYLMETHYL]-PHENYLAMINO)-ACETIC ACID, SODIUM SALT
Synonyms
CS-1407;Rigosertib;Rigosertib(acid);rigosertib(PI3K/Plk1 inhibitor)ORPHAN DRUG;3: PN: WO2006074149 PAGE: 45 claiMed sequence;(E)-2-((2-Methoxy-5-(((2,4,6-triMethoxystyryl)sulfonyl)Methyl)phenyl)aMino)acetic acid;N-[2-Methoxy-5-[[[(1E)-2-(2,4,6-trimethoxyphenyl)ethenyl]sulfonyl]methyl]phenyl]glycine;Glycine, N-[2-Methoxy-5-[[[(1E)-2-(2,4,6-triMethoxyphenyl)ethenyl]sulfonyl]Methyl]phenyl]-;(2-METHOXY-5-[2-(2,4,6-TRIMETHOXY-PHENYL)-ETHENESULFONYLMETHYL]-PHENYLAMINO)-ACETIC ACID, SODIUM SALT;PI3K,Polo-like Kinase (PLK),Rigosertib,Phosphoinositide 3-kinase,Apoptosis,ON 01910,Inhibitor,inhibit,ON01910
CBNumber:
CB92457038
Molecular Formula:
C21H25NO8S
Molecular Weight:
451.49
MOL File:
592542-59-1.mol
MSDS File:
SDS
Modify Date:
2024/7/2 8:55:41
Request For Quotation

(2-METHOXY-5-[2-(2,4,6-TRIMETHOXY-PHENYL)-ETHENESULFONYLMETHYL]-PHENYLAMINO)-ACETIC ACID, SODIUM SALT Properties

Melting point 172-174 °C(Solv: acetone (67-64-1))
Boiling point 756.1±60.0 °C(Predicted)
Density 1.332±0.06 g/cm3(Predicted)
storage temp. Store at -20°C,unstable in solution, ready to use.
solubility Soluble in DMSO
form Powder
pka 4.23±0.20(Predicted)
color White to light yellow

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P305+P351+P338

(2-METHOXY-5-[2-(2,4,6-TRIMETHOXY-PHENYL)-ETHENESULFONYLMETHYL]-PHENYLAMINO)-ACETIC ACID, SODIUM SALT Chemical Properties,Uses,Production

Uses

Rigosertib is a microtubule destabilizing agent which may be employed in the treatment of high-?risk myelodysplastic syndrome.

(2-METHOXY-5-[2-(2,4,6-TRIMETHOXY-PHENYL)-ETHENESULFONYLMETHYL]-PHENYLAMINO)-ACETIC ACID, SODIUM SALT Preparation Products And Raw materials

Raw materials

908344-08-1 1330633-86-7 1330633-87-8 4-METHOXY-3-NITROBENZYL ALCOHOL 97 (E)-2',4',6'-triMethoxystyryl-4-Methoxy-3-aMinobenzylsulfone, (E)-5-((2,4,6-triMethoxystyrylsulfonyl)Methyl)-2-MethoxybenzeneaMine
4-Methoxy-3-nitrobenzyl bromide 908344-21-8 4-Methoxy-3-nitrobenzylsulfonylacetic acid (E)-Methyl 2-(2-Methoxy-5-((2′,4′,6′-triMethoxystyrylsulfonyl)Methyl)phenylaMino)acetate 4-METHOXY-3-NITROBENZALDEHYDE
(4-METHOXY-3-NITROBENZYL)THIO]ACETIC ACID 4-Methyl-2-nitroanisole
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Preparation Products

(2-METHOXY-5-[2-(2,4,6-TRIMETHOXY-PHENYL)-ETHENESULFONYLMETHYL]-PHENYLAMINO)-ACETIC ACID, SODIUM SALT Suppliers

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CLEARSYNTH LABS LTD. 58
Pharmaffiliates Analytics and Synthetics P. Ltd 58
Pharma Affiliates 58
TargetMol Chemicals Inc. 58
InvivoChem 58
ZHEJIANG JIUZHOU CHEM CO., LTD 58
LEAPCHEM CO., LTD. 58
Suzhou ARTK Medchem Co., Ltd. 58
Amadis Chemical Company Limited 58
ApexBio Technology 58

592542-59-1((2-METHOXY-5-[2-(2,4,6-TRIMETHOXY-PHENYL)-ETHENESULFONYLMETHYL]-PHENYLAMINO)-ACETIC ACID, SODIUM SALT)Related Search:

Rigosertib sodium
(2-METHOXY-5-[2-(2,4,6-TRIMETHOXY-PHENYL)-ETHENESULFONYLMETHYL]-PHENYLAMINO)-ACETIC ACID, SODIUM SALT Glycine, N-[2-Methoxy-5-[[[(1E)-2-(2,4,6-triMethoxyphenyl)ethenyl]sulfonyl]Methyl]phenyl]- (E)-2-((2-Methoxy-5-(((2,4,6-triMethoxystyryl)sulfonyl)Methyl)phenyl)aMino)acetic acid 3: PN: WO2006074149 PAGE: 45 claiMed sequence Rigosertib N-[2-Methoxy-5-[[[(1E)-2-(2,4,6-trimethoxyphenyl)ethenyl]sulfonyl]methyl]phenyl]glycine rigosertib(PI3K/Plk1 inhibitor)ORPHAN DRUG CS-1407 Rigosertib(acid) PI3K,Polo-like Kinase (PLK),Rigosertib,Phosphoinositide 3-kinase,Apoptosis,ON 01910,Inhibitor,inhibit,ON01910 592542-59-1 C21H24NNaO8S C21H25NO8S Antineoplastic protein Kinase inhibitors APIS