D609
- CAS No.
- 83373-60-8
- Chemical Name:
- D609
- Synonyms
- D609;D609 ,98%;D609,D-609;D-609 POTASSIUM;D609 POTASSIUM SALT;D609, 10 mM in DMSO;D609 potassium salt,98%;Tricyclodecan-9-yl xanthate;Tricyclodecan-9-yl xanthogenate;tricyclodecane-9-yl-xanthogenate
- CBNumber:
- CB9249743
- Molecular Formula:
- C11H17KOS2
- Molecular Weight:
- 268.47
- MOL File:
- 83373-60-8.mol
- MSDS File:
- SDS
- Modify Date:
- 2025/1/27 9:38:02
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302 | |||||||||
| Precautionary statements | P264-P270-P301+P312-P330-P501 | |||||||||
| Risk Statements | 22 | |||||||||
| Safety Statements | 24/25 | |||||||||
| WGK Germany | 3 | |||||||||
| HS Code | 29333990 | |||||||||
| NFPA 704 |
|
D609 price More Price(3)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | T8543 | O-Tricyclo[5.2.1.02,6]dec-9-yl dithiocarbonate potassium salt ≥95%, solid | 83373-60-8 | 5MG | ₹26207.33 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | T8543 | O-Tricyclo[5.2.1.02,6]dec-9-yl dithiocarbonate potassium salt ≥95%, solid | 83373-60-8 | 25MG | ₹104353 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | 251400 | D609, Potassium Salt - CAS 83373-60-8 - Calbiochem Selective inhibitor of phosphatidylcholine (PC)-specific phospholipase C (Ki = 5-10 μM). | 83373-60-8 | 5MG | ₹19050 | 2022-06-14 | Buy |
D609 Chemical Properties,Uses,Production
Description
D609 is a xanthate and a competitive inhibitor of phosphatidylcholine-specific phospholipase C (PC-PLC; Ki = 6.4 μM). It has no effect on bacterial phosphatidylinositol-specific PLC, bovine pancreatic PLA2, or phospholipase D. D609 reduces sphingomyelin synthase activity by 55.5 and 90.5% in membrane preparations when used at concentrations of 100 and 200 mg/ml, respectively. Similar to other xanthates, D609 has antioxidant, antiviral, and anti-tumor activities. In addition, it has anti-inflammatory actions, inhibiting LPS-stimulated expression of nitric oxide synthase (NOS) in phagocytes (IC50 = 20 μg/ml) and IL-1β-induced expression of vascular cell adhesion molecule 1 (VCAM-1) in endothelial cells.
Chemical Properties
white to off-white solid
Uses
D609 has been used as a phosphatidylcholine-specific phospholipase C (PC-PLC) inhibitor in mouse bone marrow derived monocytes. D609 has also been reported to significantly reduce the elevated levels of phosphatidylethanolamine binding protein 1 (PEBP1) in apolipoprotein E-/- mice.
Biological Activity
Selective competitive phosphatidyl choline-specific phospholipase C (PC-PLC) inhibitor (K i = 6.4 μ M); antiviral and antitumor agent. Suppresses LPS- and IFN γ -induced NO production (IC 50 = 20 mg/ml) and blocks oxidative glutamate toxicity in nerve cells. Antioxidant in vivo .
D609 Preparation Products And Raw materials
Raw materials
Preparation Products
D609 Suppliers
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6257 | 58 | Inquiry |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | China | 33024 | 60 | Inquiry |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | China | 49732 | 58 | Inquiry |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | United States | 32159 | 58 | Inquiry |
| Career Henan Chemica Co | +86-0371-86658258 +8613203830695 | China | 30231 | 58 | Inquiry |
| Labnetwork lnc. | +86-27-50766799 +8618062016861 | China | 19987 | 58 | Inquiry |
| Aladdin Scientific | United States | 57505 | 58 | Inquiry | |
| Amadis Chemical Company Limited | 571-89925085 | China | 131957 | 58 | Inquiry |
| Shanghai Hao Biological Technology Co., Ltd. | 021-80370006 13585899102 | CHINA | 6793 | 58 | Inquiry |
| Shenzhen Xinbosheng Biological Technology Co., Ltd. | 0755-26755892 | CHINA | 6151 | 58 | Inquiry |
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