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LEE011 (succinate)

LEE011 (succinate) Structure
CAS No.
1374639-75-4
Chemical Name:
LEE011 (succinate)
Synonyms
Ribociclib succinate;RIBOCICLIB SUCCINATE (LEE011);Ribociclib succite;LEE011 (succinate);1374639-75-4 LEE011 (succinate);Ribociclib Succinate (Kisqali);RIBOCICLIB SUCCINATE (LEE011 SUCCINATE);LEE-011 succinate salt, Ribociclib succinate salt;7-cyclopentyl-N,N-dimethyl-2-((5-(piperazin-1-yl)pyridin-2-yl)amino)-7H-pyrrolo[2,3-d]pyrimidine-6-carboxamide succinate
CBNumber:
CB92682010
Molecular Formula:
C27H36N8O5
Molecular Weight:
552.64
MOL File:
1374639-75-4.mol
Modify Date:
2023/9/20 16:43:00
Request For Quotation

LEE011 (succinate) Properties

Melting point >160oC (dec.)
storage temp. Refrigerator
solubility DMSO (Slightly), Methanol (Slightly)
form Solid
color Pale Beige

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS06,GHS08,GHS09
Signal word  Danger
Hazard statements  H301-H315-H319-H372-H400
Precautionary statements  P273-P301+P310-P305+P351+P338-P314

LEE011 (succinate) Chemical Properties,Uses,Production

Uses

LEE011 is an orally bioavailable and highly specific CDK4/6 (cyclin-dependent kinase 4/6) inhibitor. LEE011 in combination with LGX818 (a V600E BRAF specific inhibitor) or BYL719 (a PIK3CA specific inhibitor) leads to robust anti-tumor activity in melanoma and breast cancer tumor models.

LEE011 (succinate) Preparation Products And Raw materials

Raw materials

Preparation Products

LEE011 (succinate) Suppliers

Global( 129)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
CHEMAZON LABORATORIES +91 9848551964 Hyderabad, India 1320 58 Inquiry
MSN LABORATORIES PRIVATE LTD +91 40 30438600 New Delhi, India 230 58 Inquiry
FRESENIUS KABI ONCOLOGY LTD +86-571-28971376 New Delhi, India 21 58 Inquiry
Pharmaffiliates Analytics and Synthetics P. Ltd +91-172-5066494 Haryana, India 6773 58 Inquiry
CLEARSYNTH LABS LTD. +91-22-45045900 Hyderabad, India 6351 58 Inquiry
SynZeal Research Pvt Ltd +1 226-802-2078 Gujarat, India 6522 58 Inquiry
Pharma Affiliates 172-5066494 Haryana, India 6761 58 Inquiry
Henan Tianfu Chemical Co.,Ltd. +86-0371-55170693 +86-19937530512 China 21669 55 Inquiry
ATK CHEMICAL COMPANY LIMITED +undefined-21-51877795 China 32760 60 Inquiry
career henan chemical co +86-0371-86658258 +8613203830695 China 29897 58 Inquiry
Supplier Advantage
CHEMAZON LABORATORIES 58
MSN LABORATORIES PRIVATE LTD 58
FRESENIUS KABI ONCOLOGY LTD 58
Pharmaffiliates Analytics and Synthetics P. Ltd 58
CLEARSYNTH LABS LTD. 58
SynZeal Research Pvt Ltd 58
Pharma Affiliates 58
Henan Tianfu Chemical Co.,Ltd. 55
ATK CHEMICAL COMPANY LIMITED 60
career henan chemical co 58

LEE011 (succinate) Spectrum

LEE011 (succinate)(1374639-75-4)1HNMR

1374639-75-4(LEE011 (succinate))Related Search:

tert-butyl 4-(6-aminopyridin-3-yl)piperazine-1-carboxylate LEE011 (hydrochloride) Ribociclib Neratinib Maleate 1-Piperazinecarboxylic acid, 4-[6-[[7-cyclopentyl-6-[(diMethylaMino)carbonyl]-7H-pyrrolo[2,3-d]pyriMidin-2-yl]aMino]-3-pyridinyl]-, 1,1-diMethylethyl ester
2-Chloro-7-cyclopentyl-N,N-dimethyl-H-pyrrolo[2,3-d]pyrimidine-6-carboxamide
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LEE011 (succinate) 7-cyclopentyl-N,N-dimethyl-2-((5-(piperazin-1-yl)pyridin-2-yl)amino)-7H-pyrrolo[2,3-d]pyrimidine-6-carboxamide succinate LEE-011 succinate salt, Ribociclib succinate salt Ribociclib Succinate (Kisqali) RIBOCICLIB SUCCINATE (LEE011 SUCCINATE) Ribociclib succite 1374639-75-4 LEE011 (succinate) Ribociclib succinate RIBOCICLIB SUCCINATE (LEE011) 1374639-75-4 C23H30N8OC4H6O4